Results 181 to 190 of about 1,746 (206)

8-Hydroxy-7-nitroquinoline-5-sulfonic Acid Monohydrate

Acta Crystallographica Section C Crystal Structure Communications, 1996
The title compound, C9H6N2O6S.H2O, is zwitterionic (i.e. 8-hydroxy-7-nitroquinolinium-5-sulfonate monohydrate) with a deprotonated sulfonic group and a protonated quinoline N atom which interacts with the hydroxy O atom. The H atom of the hydroxy group is distal to the N atom and is involved in an interaction with an O atom of the nitro group, which is
T P, Balasubramanian, P T, Muthiah
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Carcinogenicity of 8-nitroquinoline in Sprague—Dawley rats

Cancer Letters, 1978
8-Nitroquinoline was added to the semisynthetic diet of outbred Sprague-Dawley rats for 48 weeks. Squamous cell carcinomas of the upper digestive tract (tongue and esophagus), but especially of the forestomach, occurred among the higher concentration groups.
M, Takahashi, T, Shirai, S, Fukushima, K, Hosoda, S, Yoshida, N, Ito   +5 more
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Mutagenicity in yeast of nitroquinolines and related compounds

Toxicology and Applied Pharmacology, 1969
Abstract A series of 14 nitroquinolines and hydroxyaminoquinolines, related to the potent water-soluble carcinogen 4-nitroquinoline 1-oxide (4-NQO), were tested for induction of respiratory-deficient mutants in Saccharomyces cerevisiae . Eight quinolines, including 4-NQO and 4-hydroxyaminoquinoline 1-oxide, were mutagenic at concentrations markedly ...
S S, Epstein, J A, Pierre
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PMR analysis of nitroquinoline 1‐Oxides

Journal of Heterocyclic Chemistry, 1972
AbstractChemical shifts and coupling values obtained from the 100 MHz pmr spectra of 12 nitrosubstituted quinoline 1‐oxide derivatives are presented. Spin‐spin decoupling, application of the paramagnetic shift reagent tris‐(1,1,1,2,2,3,3‐heptafluoro‐7,7‐dimethyl‐4,6‐octanedione) europium (III), and calculations of theoretical spectra were used in ...
Robert Roe, J. S. Paul, P.O'B. Montgomery   +2 more
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ChemInform Abstract: Oxidative Methylamination of Nitroquinolines.

ChemInform, 1993
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
M. WOZNIAK, M. GRZEGOZEK
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Interactions of 4-nitroquinoline 1-oxide with deoxyribodinucleotides

Biochemistry, 1979
The interactions of 4-nitroquinoline 1-oxide (NQO), a potent mutagen and carcinogen, with several self- and non-self-complementary deoxydinucleotides were probed by using absorption spectra of the charge transfer bands and 1H and 13C NMR spectra. Absorption spectra were analyzed by using Benesi-Hildebrand-type equations to yield stoichiometries and ...
S A, Winkle, I, Tinoco
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Reduction of 6‐nitroquinoline with phosphine

Recueil des Travaux Chimiques des Pays-Bas, 1964
AbstractReduction of 6‐nitroquinoline with phosphine under the conditions described by Buckler yields 6,6′‐azo‐5,5′‐diquinolyl along with 6,6′‐azoxyquinoline.
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Antileishmanial pharmacomodulation in 8-nitroquinolin-2(1H)-one series

Bioorganic & Medicinal Chemistry, 2015
An antileishmanial pharmacomodulation at position 4 of 8-nitroquinolin-2(1H)-one was conducted by using the Sonogashira and Suzuki-Miyaura coupling reactions. A series of 25 derivatives was tested in vitro on the promastigote stage of Leishmania donovani along with an in vitro cytotoxicity evaluation on the human HepG2 cell line.
Kieffer, Charline, Cohen, Anita, Verhaeghe, Pierre, Paloque, Lucie, Hutter, Sébastien, Castera-Ducros, Caroline, Laget, Michèle, Rault, Sylvain, Valentin, Alexis, Rathelot, Pascal, Azas, Nadine, Vanelle, Patrice   +11 more
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Mutagenicity of 4-nitroquinoline 1-oxide in the Muta™Mouse

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 1999
As part of a collaborative study, the Mammalian Mutagenesis Study Group (MMS), a sub-organization of the Environmental Mutagen Society of Japan (JEMS) conducted mutagenicity tests in MutaMouse. Using a positive selection method, we studied the organ-specificity and time dependence of mutation induction by 4-nitroquinoline 1-oxide (4NQO).
M, Nakajima, M, Kikuchi, K, Saeki, Y, Miyata, M, Terada, F, Kishida, R, Yamamoto, C, Furihata, S W, Dean   +8 more
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Vicarious Nucleophilic Substitution in Nitroquinolines¹⁾

Liebigs Annalen der Chemie, 1986
Abstract5‐Nitro‐, 6‐nitro‐, and 8‐nitroquinoline react with the carbanions of chloromethyl phenyl sulfone, chloro‐N,N‐dimethylmethanesulfonamide and substituted acetonitriles XCH2CN (X = OPh, SPh, Cl) giving products of the vicarious nucleophilic substitution of hydrogen predominantly or exclusively at positions 6, 5, and 7, respectively.
Mieczyslaw Mąkosza, Andrzej Kinowski, Witold Danikiewicz, Boguslaw Mudryk   +3 more
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