Results 21 to 30 of about 25,127 (201)

Regulation of Apoptosis by Nitrosative Stress [PDF]

BMB Reports, 2002
Nitrosative stress can prevent or induce apoptosis. It occurs via S-nitrosylation by the interaction of nitric oxide (NO) with the biological thiols of proteins. Cellular redox potential and non-heme iron content determine S-nitrosylation. Apoptotic cell death is inhibited by S-nitrosylation of the redox-sensitive thiol in the catalytic site of caspase
Ki-Mo, Kim, Peter K M, Kim, Young-Guen, Kwon, Se-Kyung, Bai, Woo-Dong, Nam, Young-Myeong, Kim   +5 more
openaire   +2 more sources

Could circulating biomarkers of nitrosative stress and protein glycoxidation be useful in patients with gastric cancer?

Frontiers in Oncology, 2023
BackgroundNitrosative stress leads to protein glycoxidation, but both processes may be strongly related to the cancer development. Therefore, the aim of this study was to assess the nitrosative stress and protein glycoxidation products in patients with ...
Justyna Dorf, Anna Pryczynicz, Joanna Matowicka-Karna, Konrad Zaręba, Piotr Żukowski, Anna Zalewska, Mateusz Maciejczyk   +6 more
doaj   +1 more source

Redox Regulation, Rather than Stress-Induced Phosphorylation, of a Hog1 Mitogen-Activated Protein Kinase Modulates Its Nitrosative-Stress-Specific Outputs

mBio, 2018
In all eukaryotic kingdoms, mitogen-activated protein kinases (MAPKs) play critical roles in cellular responses to environmental cues. These MAPKs are activated by phosphorylation at highly conserved threonine and tyrosine residues in response to ...
Carmen Herrero-de-Dios, Alison M. Day, Anna T. Tillmann, Stavroula L. Kastora, David Stead, Paula S. Salgado, Janet Quinn, Alistair J. P. Brown   +7 more
doaj   +1 more source

Nitrosative stress and nitrated proteins in trichloroethene-mediated autoimmunity. [PDF]

PLoS ONE, 2014
Exposure to trichloroethene (TCE), a ubiquitous environmental contaminant, has been linked to a variety of autoimmune diseases (ADs) including SLE, scleroderma and hepatitis. Mechanisms involved in the pathogenesis of ADs are largely unknown.
Gangduo Wang, Jianling Wang, Xuemei Luo, G A Shakeel Ansari, M Firoze Khan   +4 more
doaj   +1 more source

Gene expression profiling data of Schizosaccharomyces pombe under nitrosative stress using differential display

Data in Brief, 2016
Excess production of nitric oxide (NO) and reactive nitrogen intermediates (RNIs) causes nitrosative stress on cells. Schizosaccharomyces pombe was used as a model to study nitrosative stress response.
Pranjal Biswas, Uddalak Majumdar, Sanjay Ghosh   +2 more
doaj   +1 more source

Interplay of two transcription factors for recruitment of the chromatin remodeling complex modulates fungal nitrosative stress response

Nature Communications, 2021
Plant and animal tissues produce nitric oxide and reactive nitrogen species that induce nitrosative stress in pathogens. Here, Jian et al. identify two transcriptional regulators in the phytopathogen Fusarium graminearum that control the nitrosative ...
Yunqing Jian, Zunyong Liu, Haixia Wang, Yun Chen, Yanni Yin, Youfu Zhao, Zhonghua Ma   +6 more
doaj   +1 more source

Does Oxidative Stress Change During Orthotopic Liver Transplantation?

Journal of Controversies in Biomedical Research, 2017
In clinical ischemia/reperfusion injury, damage resulting from oxidative and nitrosative stress is generally considered crucial for graft functioning.
Dimitrios Tsikas
doaj   +1 more source

Neuro-oxidative-nitrosative stress in sepsis [PDF]

Journal of Cerebral Blood Flow & Metabolism, 2011
Neuro-oxidative-nitrosative stress may prove the molecular basis underlying brain dysfunction in sepsis. In the current review, we describe how sepsisinduced reactive oxygen and nitrogen species (ROS/RNS) trigger lipid peroxidation chain reactions throughout the cerebrovasculature and surrounding brain parenchyma, due to failure of
Berg, Ronan M G, Møller, Kirsten, Bailey, Damian M   +2 more
openaire   +3 more sources

Proteome‐Wide Target Identification Using Reactive Metallo‐Scaffolds (r‐mS): A Platform for Metallodrug Discovery

Angewandte Chemie, EarlyView.
Re‐envisioning the Ligandable Proteome: Reactive Metallo‐Scaffolds (r‐mS) combine non‐covalent protein engagement by a metallo‐scaffold with covalent cysteine capture through a tethered chloroacetamide warhead. Chemoproteomic profiling reveals unique enzyme engagement including ligases, kinases and methyltransferases, highlighting opportunities for ...
Jessica E. Waters, Harry Wilders, George S. Biggs, Mika Kintzel, Emma E. Cawood, Jonathan Bailey, Sarah Maslen, Yew Mun Yip, Mason Wakley, Ioannis G. Riziotis, Thomas W. Rees, Joanna Redmond, J. Mark Skehel, David House, Jacob Bush, Jeannine Hess   +15 more
wiley   +2 more sources

Bariatric Surgery Normalizes Protein Glycoxidation and Nitrosative Stress in Morbidly Obese Patients

Antioxidants, 2020
The results of recent studies indicate the key role of nitrosative stress and protein oxidative damage in the development of morbid obesity. Nevertheless, the effect of bariatric surgery on protein oxidation/glycation and nitrosative/nitrative stress is ...
Barbara Choromańska, Piotr Myśliwiec, Magdalena Łuba, Piotr Wojskowicz, Hanna Myśliwiec, Katarzyna Choromańska, Jacek Dadan, Małgorzata Żendzian-Piotrowska, Anna Zalewska, Mateusz Maciejczyk   +9 more
doaj   +1 more source