Results 11 to 20 of about 12,165 (156)

New acyloxy nitroso compounds with improved water solubility and nitroxyl (HNO) release kinetics and inhibitors of platelet aggregation. [PDF]

Bioorg Med Chem, 2015
Mohamed HA, Abdel-Aziz M, Abuo-Rahma Gel-D, King SB.   +3 more
europepmc   +2 more sources

Characterization of T-Cell Responses to SMX and SMX-NO in Co-Trimoxazole Hypersensitivity Patients Expressing HLA-B*13:01

Frontiers in Immunology, 2021
HLA-B*13:01-positive patients in Thailand can develop frequent co-trimoxazole hypersensitivity reactions. This study aimed to characterize drug-specific T cells from three co-trimoxazole hypersensitive patients presenting with either Stevens-Johnson ...
Jirawat Pratoomwun, Jirawat Pratoomwun, Paul Thomson, Kanoot Jaruthamsophon, Rawiporn Tiyasirichokchai, Pimonpan Jinda, Ticha Rerkpattanapipat, Wichittra Tassaneeyakul, Nontaya Nakkam, Pawinee Rerknimitr, Jettanong Klaewsongkram, Yuttana Srinoulprasert, Munir Pirmohamed, Dean J. Naisbitt, Chonlaphat Sukasem   +14 more
doaj   +1 more source

Kinetic study on the reaction of sodium nitrite with neurotransmitters secreted in the stomach

Scientific Reports, 2023
Nitroso-compounds are potentially mutagenic and carcinogenic compounds due to their ability to alkylate DNA bases. One of the most common sources of human exposure to nitroso-compounds is their formation in the acidic environment of the stomach by the ...
Mario González-Jiménez, M. Pilar García-Santos, Blanca Bermejo Tesón, Ángel L. Fuentes de Arriba, Jorge Arenas Valgañón, Emilio Calle, Julio Casado   +6 more
doaj   +1 more source

SUBSTITUTED 4-NITROSOPYRAZOLES IN THE DIELS-ALDER REACTION

Siberian Journal of Life Sciences and Agriculture, 2021
Background. 4-Nitrosopyrazoles have become widespread in the pharmaceutical industry and in chemistry due to their high reactivity and biological activity. However, the interaction of 3,5-substituted 4-nitroso-1H-pyrazoles with diene hydrocarbons has not
Darya S. Volkova, Arkadiy A. Popov, Evgeny V. Root, Alexey A. Kukushkin, George A. Suboch   +4 more
doaj   +1 more source

Carcinogenic effects of N-nitroso compounds in the environment

Environment Conservation Journal, 2020
N-nitroso compounds (NOC) are produced by the acid catalyzed reaction of nitrite with certain nitrogen compounds. The gastrointestinal tract (GI) is the main site for the formation of reactive nitrogen species (RNS).
Divya Jain, Priya Chaudhary, Nidhi Varshney, Pracheta Janmeda   +3 more
doaj   +1 more source

A new type of convergent paired electrochemical synthesis of sulfonamides under green and catalyst-free conditions

Scientific Reports, 2023
Our main goal in this work is to synthesize valuable sulfonamide compounds according to the principles of green chemistry and also to present a unique convergent paired mechanism for their synthesis.
Pouria Patoghi, Ali Sadatnabi, Davood Nematollahi   +2 more
doaj   +1 more source

Correlation of precancerous lesion incidence with duodenogastric reflux and N-nitroso compound duration at reflux and antireflux stomach surgery: An experimental study [PDF]

Vojnosanitetski Pregled, 2018
Background/Aim. Duodenogastric reflux occurs after gastroenteroanastomosis, with or without resection of the stomach (Billroth I, Billroth II), after vagotomy and pyloroplasty, gastroduodenostomy as well as in conservatively treated patients.
Zlatić Aleksandar, Marinković Mirjana, Mihailović Dragan, Radojković Milan, Radovanović-Dinić Biljana, Đorđević Miodrag, Korica Milan, Veljković Radovan   +7 more
doaj   +1 more source

Investigation of Escherichia coli O157:H7 Survival and Interaction with Meal Components during Gastrointestinal Digestion

Foods, 2021
Escherichia coli O157:H7 is responsible for foodborne poisoning, incriminating contaminated animal food and especially beef meat. This species can survive in the digestive tract, but, up to now, very few studies have considered its survival during the ...
Diane de La Pomelie, Sabine Leroy, Régine Talon, Philippe Ruiz, Philippe Gatellier, Véronique Santé-Lhoutellier   +5 more
doaj   +1 more source

Aromatic C-Nitroso Compounds and Their Dimers: A Model for Probing the Reaction Mechanisms in Crystalline Molecular Solids

Crystals, 2017
This review is focused on the dimerization and dissociation of aromatic C-nitroso compounds and their dimers, the reactions that could be used as a convenient model for studying the thermal organic solid-state reaction mechanisms. This molecular model is
Ivana Biljan, Hrvoj Vančik
doaj   +1 more source

[3+3]-Annulation of Cyclic Nitronates with Vinyl Diazoacetates: Diastereoselective Synthesis of Partially Saturated [1,2]Oxazino[2,3-b][1,2]oxazines and Their Base-Promoted Ring Contraction to Pyrrolo[1,2-b][1,2]oxazine Derivatives

Molecules, 2023
A rhodium(II)-catalyzed reaction of cyclic nitronates (5,6-dihydro-4H-1,2-oxazine N-oxides) with vinyl diazoacetates proceeds as a [3+3]-annulation producing bicyclic unsaturated nitroso acetals (4a,5,6,7-tetrahydro-2H-[1,2]oxazino[2,3-b][1,2]oxazines ...
Yulia A. Antonova, Yulia V. Nelyubina, Sema L. Ioffe, Andrey A. Tabolin   +3 more
doaj   +1 more source