Results 31 to 40 of about 12,165 (156)

Associação entre fatores da dieta e tumores de cérebro em adultos: uma revisão da literatura Association between dietary factors and brain tumors in adults: a review

Cadernos de Saúde Pública, 2001
Desenvolveu-se uma revisão da literatura científica publicada entre 1986 e 1999, sobre a associação entre fatores da dieta e os tumores de cérebro em adultos, com o objetivo de descrever as associações observadas e discutir os aspectos metodológicos que ...
Rosângela Alves Pereira, Sérgio Koifman   +1 more
doaj   +1 more source

Acyloxy nitroso compounds inhibit LIF signaling in endothelial cells and cardiac myocytes: evidence that STAT3 signaling is redox-sensitive. [PDF]

PLoS ONE, 2012
We previously showed that oxidative stress inhibits leukemia inhibitory factor (LIF) signaling by targeting JAK1, and the catalytic domains of JAK 1 and 2 have a cysteine-based redox switch. Thus, we postulated that the NO sibling and thiophylic compound,
Carlos Zgheib, Mazen Kurdi, Fouad A Zouein, Barak W Gunter, Brian A Stanley, Joe Zgheib, Damian G Romero, S Bruce King, Nazareno Paolocci, George W Booz   +9 more
doaj   +1 more source

Design and Synthesis of C-1 Methoxycarbonyl Derivative of Narciclasine and Its Biological Activity

Molecules, 2022
A 15-step chemoenzymatic total synthesis of C-1 methoxycarbonyl narciclasine (10) was accomplished. The synthesis began with the toluene dioxygenase-mediated dihydroxylation of ortho-dibromobenzene to provide the corresponding cis-dihydrodiol (12) as a ...
Lihi Habaz, Korey Bedard, Mitchell Smith, Liqin Du, Alexander Kornienko, Tomas Hudlicky   +5 more
doaj   +1 more source

Preparations ofC-Nitroso Compounds [PDF]

Chemical Reviews, 2004
The discovery of important roles of C-nitroso compounds in various biological metabolic processes has generated a renewed interest in the general chemical properties of nitrosoalkanes (R–N=O; R =alkyl) and nitrosoarenes (ArNO; Ar =aryl), two important subsets of this general class of compounds.
Brian G, Gowenlock, George B, Richter-Addo   +1 more
openaire   +2 more sources

Nitric oxide release from the S-nitrosothiol zinc phthalocyanine complex by flash photolysis

Brazilian Journal of Medical and Biological Research, 2003
The photogeneration of nitric oxide (NO) using laser flash photolysis was investigated for S-nitroso-glutathione (GSNO) and S-nitroso-N-acetylcysteine (NacySNO) at pH 6.4 (PBS/HCl) and 7.4 (PBS).
J.C.G. Rotta, C.N. Lunardi, A.C. Tedesco
doaj   +1 more source

Stereo- and regioselectivity of the hetero-Diels–Alder reaction of nitroso derivatives with conjugated dienes

Beilstein Journal of Organic Chemistry, 2016
The hetero-Diels–Alder reaction between a nitroso dienophile and a conjugated diene to give the 3,6-dihydro-2H-1,2-oxazine scaffold is useful for the synthesis of many biologically interesting molecules due to the diverse opportunities created by ...
Lucie Brulíková, Aidan Harrison, Marvin J. Miller, Jan Hlaváč   +3 more
doaj   +1 more source

Nitrosamines crisis in pharmaceuticals − Insights on toxicological implications, root causes and risk assessment: A systematic review

Journal of Pharmaceutical Analysis
The presence of N-nitroso compounds, particularly N-nitrosamines, in pharmaceutical products has raised global safety concerns due to their significant genotoxic and mutagenic effects.
Hemanth P.R. Vikram, Tegginamath Pramod Kumar, Gunjan Kumar, Narasimha M. Beeraka, Rajashree Deka, Sheik Mohammed Suhail, Sandeep Jat, Namitha Bannimath, Gayatiri Padmanabhan, Ravandur S. Chandan, Pramod Kumar, Bannimath Gurupadayya   +11 more
doaj   +1 more source

Anticancer and Anti-Inflammatory Activities of Some New Pyrazolo[3,4-b]pyrazines

Molecules, 2018
New derivatives of pyrazolo[3,4-b]pyrazines and related heterocycles were synthesized using 5-amino-3-methyl-4-nitroso-1-phenyl-pyrazole (1) as a starting material. The 5-acetyl derivative 15 was shown to be a useful key intermediate for the synthesis of
Hussein El-Kashef, Talaat El-Emary, Pierre Verhaeghe, Patrice Vanelle, Maha Samy   +4 more
doaj   +1 more source

nitroso compounds

, 2014
Citation: 'nitroso compounds' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.N04169 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Synthesis and antibacterial activity of some new 3-hydroxy-2-naphthoic acid hydrazide derivatives for dyeing polyester fabrics

Journal of Saudi Chemical Society, 2016
Dibenzobarallene was used as a key intermediate for the synthesis of 2-(3-hydroxy-2-naphthoyl)-3,4,4a,5,10,10a-hexahydro-1H-5,10-benzenobenzo[g]phthalazine-1,4-dione (2).
Abd El-Galil M. Khalil, Moged A. Berghot, Moustafa A. Gouda   +2 more
doaj   +1 more source