Results 1 to 10 of about 18,603 (231)

NTyroSite: Computational Identification of Protein Nitrotyrosine Sites Using Sequence Evolutionary Features [PDF]

open access: yesMolecules, 2018
Nitrotyrosine is a product of tyrosine nitration mediated by reactive nitrogen species. As an indicator of cell damage and inflammation, protein nitrotyrosine serves to reveal biological change associated with various diseases or oxidative stress ...
Md. Mehedi Hasan   +4 more
doaj   +2 more sources

Curcumin Administration Improves Force of mdx Dystrophic Diaphragm by Acting on Fiber-Type Composition, Myosin Nitrotyrosination and SERCA1 Protein Levels

open access: yesAntioxidants, 2023
The vegetal polyphenol curcumin displays beneficial effects against skeletal muscle derangement induced by oxidative stress, disuse or aging. Since oxidative stress and inflammation are involved in the progression of muscle dystrophy, the effects of ...
Luisa Gorza   +8 more
doaj   +1 more source

Relationship between Oxidative Stress and Left Ventricle Markers in Patients with Chronic Heart Failure

open access: yesCells, 2023
Oxidative stress is proposed in the literature as an important player in the development of CHF and correlates with left ventricle (LV) dysfunction and hypertrophy in the failing heart.
Aušra Mongirdienė   +5 more
doaj   +1 more source

Preventive effect of N-stearoylethanolamine on memory disorders, blood and brain biochemical parameters in rats with experimental scopolamine-induced cognitive impairment [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2018
The impairment of cognitive functions is the most studied medical and social problem nowadays. The aim of this study was to evaluate the protective effects of N-stearoylethanolamine (NSE) on memory state, blood and brain biochemical parameters in rats ...
T. M. Horid’ko   +11 more
doaj   +1 more source

In Vitro Induction and Characterization of Polyploid Hydrangea macrophylla and H. serrata

open access: yesHortScience, 2021
Hydrangea macrophylla (Thunb.) Ser. and H. serrata (Thunb.) Ser. are popular and commercially important landscape and floriculture crops. Although both species are typically diploid, induced polyploids often exhibit horticulturally valuable traits ...
Lauren E. Deans   +3 more
doaj   +1 more source

Amino Acid Signature of Oxidative Stress in Patients with Type 2 Diabetes: Targeted Exploratory Metabolomic Research

open access: yesAntioxidants, 2021
Oxidative stress plays a key role in the development of chronic diabetes-related complications. Previous metabolomic studies showed a positive association of diabetes and insulin resistance with branched-chain amino acids (AAs) and aromatic AAs.
Cornelia G. Bala   +4 more
doaj   +1 more source

Sitagliptin Modulates Oxidative, Nitrative and Halogenative Stress and Inflammatory Response in Rat Model of Hepatic Ischemia-Reperfusion

open access: yesAntioxidants, 2021
A possibility of repurposing sitagliptin, a well-established antidiabetic drug, for alleviating injury caused by ischemia-reperfusion (IR) is being researched.
Małgorzata Trocha   +7 more
doaj   +1 more source

Nitric oxide synthase activity and endogenous inhibitors in rats recovered from allergic encephalomyelitis

open access: yesMemorias do Instituto Oswaldo Cruz, 2005
We have previously reported that in comparison with normal rats, the presence of experimental allergic encephalomyelitis (EAE) leads to decreased endogenous inhibitory activity (EIA) of Ca2+-dependent nitric oxide synthase (NOS) in both brain and serum ...
SA Teixeira   +4 more
doaj   +1 more source

In vitro production of peroxynitrite by haemocytes from marine bivalves: C-ELISA determination of 3-nitrotyrosine level in plasma proteins from Mytilus galloprovincialis and Crassostrea gigas

open access: yesBMC Immunology, 2001
Background Peroxynitrite is increasingly proposed as a contributor to defence system in marine bivalve. It can be formed by combinaison of superoxide and nitric oxide, and can react with tyrosine residues of proteins giving rise to 3-nitrotyrosine ...
Romestand Bernard, Torreilles Jean
doaj   +1 more source

Impact of Protein Nitration on Influenza Virus Infectivity and Immunogenicity

open access: yesMicrobiology Spectrum, 2022
Influenza viruses are deadly respiratory pathogens of special importance due to their long history of global pandemics. During influenza virus infections, the host responds by producing interferons, which activate interferon-stimulated genes (ISGs ...
Harrison Dulin   +6 more
doaj   +1 more source

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