Results 11 to 20 of about 19,423 (111)

A Method for Selective Enrichment and Analysis of Nitrotyrosine-Containing Peptides in Complex Proteome Samples

open access: yes, 2007
Elevated levels of protein tyrosine nitration have been found in various neurodegenerative diseases and age-related pathologies. Until recently, however, the lack of an efficient enrichment method has prevented the analysis of this important low-level ...
Mark H. Chin (2314447)   +11 more
core   +2 more sources

Investigating protein 3-nitrotyrosine using bioinformatics, biochemistry and chemical derivatisation [PDF]

open access: yes, 2013
3-nitrotyrosine is a post-translational modification on tyrosine residues detected under a range of pathological conditions. In initial studies this post-translational modification was considered a benign marker of radical oxygen species; however in more
Ng, John Yee Nok
core   +1 more source

In vivo myocardial superoxide and nitrotyrosine levels.

open access: yes, 2018
Myocardial (A) superoxide was assessed by chemiluminescence, (B) DHE staining and quantitative analysis, (C) nitrotyrosine by ELISA, and (D) nitrotyrosine immunoreactive staining and quantitative analysis from the border zone.
Shinn-Zong Lin (217003)   +2 more
core   +1 more source

A schematic drawing to show protein nitrotyrosine.

open access: yes, 2014
A schematic drawing to show protein nitrotyrosine.
Ling-Yun Wu (21548)   +5 more
core   +1 more source

MHR leads to nitrotyrosine formation in BEC that is lowered by DPI.

open access: yes, 2013
Using immunohistochemical anti-nitrotyrosine stainings we detected only small amounts of nitrotyrosine in solvent treated normoxic controls (A). In contrast significantly higher amounts of nitrotyrosine were detected in BEC exposed towards MHR in a ...
Christoph M. Zehendner (294872)   +6 more
core   +1 more source

Generation of novel recombinant antibodies against nitrotyrosine by antibody phage display

open access: yes, 2011
Nitrotyrosine is a posttranslational protein modification that occurs under oxidative and nitrosative stress, and plays an important role in numerous pathological conditions. To analyse nitrotyrosine formation several commercial monoclonal and polyclonal
Moergeli, S   +10 more
core   +2 more sources

Nitrotyrosine formation with endotoxin-induced kidney injury detected by immunohistochemistry

open access: yes, 1999
The presence of nitrotyrosine in the kidney has been associated with several pathological conditions. In the present study, we investigated nitrotyrosine formation in rat kidney after animals received endotoxin for 24 h.
Karen Davis   +4 more
core   +1 more source

Assay of 3-nitrotyrosine in tissues and body fluids by liquid chromatography with tandem mass spectrometric detection

open access: yes, 2008
3-Nitrotyrosine (3-NT) is a marker of protein nitration in physiological systems. It is present as 3-nitrotyrosine residues in proteins of tissue, extracellular matrix, plasma, and other body fluids and food.
Rabbani, Naila   +3 more
core   +1 more source

LRP blocked iNOS expression and nitrotyrosine after stroke.

open access: yes, 2013
A and C. Representative protein bands of iNOS and quantitative results in the penumbra are shown for control ischemia. B and D. Representative protein bands of iNOS in the penumbra and quantitative results for the animals receiving control ischemia and ...
Chuancheng Ren (333501)   +3 more
core   +1 more source

Nitration of endogenous para-hydroxyphenylacetic acid and the metabolism of nitrotyrosine

open access: yes, 2003
Reactive nitrogen species, such as peroxynitrite, can nitrate tyrosine in proteins to form nitrotyrosine. Nitrotyrosine is metabolized to 3-nitro-4-hydroxyphenylacetic acid (NHPA), which is excreted in the urine.
Orie, N.N.   +13 more
core   +1 more source

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