Bioinformatics analysis reveals biophysical and evolutionary insights into the 3-nitrotyrosine post-translational modification in the human proteome [PDF]
Open Biology, 2013 Protein 3-nitrotyrosine is a post-translational modification that commonly arises from the nitration of tyrosine residues. This modification has been detected under a wide range of pathological conditions and has been shown to alter protein function ...
John Y. Ng +2 more
doaj +4 more sources
Flunisolide Decreases Exhaled Nitric Oxide and Nitrotyrosine Levels in Asthmatic Children [PDF]
Mediators of Inflammation, 2006 Background. Exhaled nitric oxide (FeNO) has been reported to be elevated in the oxidative stress involved in asthmatic patients, and the reaction of nitric oxide (NO) with superoxide anions results in the formation of nitrotyrosine.
A. Bodini +6 more
doaj +2 more sources
Hepatology, EarlyView., 2022 Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro +17 more
wiley +1 more source
Quantification of nitrotyrosine in nitrated proteins [PDF]
Analytical and Bioanalytical Chemistry, 2010 For kinetic studies of protein nitration reactions, we have developed a method for the quantification of nitrotyrosine residues in protein molecules by liquid chromatography coupled to a diode array detector of ultraviolet-visible absorption. Nitrated bovine serum albumin (BSA) and nitrated ovalbumin (OVA) were synthesized and used as standards for the
Yang, H., Zhang, Y., Pöschl, U.
openaire +3 more sources
Role of Hyperglycemia in Nitrotyrosine Postprandial Generation [PDF]
Diabetes Care, 2002 OBJECTIVE—Recently, much attention has been paid to the possibility that postprandial hyperglycemia may be a cardiovascular risk factor in diabetes. Oxidative stress has been involved in the pathogenesis of diabetic complications, and increased plasma levels of nitrotyrosine, a product of peroxynitrite action, have been found in the plasma of diabetic ...
CERIELLO, Antonio +9 more
openaire +2 more sources
A Method for Selective Enrichment and Analysis of Nitrotyrosine-Containing Peptides in Complex Proteome Samples [PDF]
, 2007 Elevated levels of protein tyrosine nitration have been found in various neurodegenerative diseases and age-related pathologies. Until recently, however, the lack of an efficient enrichment method has prevented the analysis of this important low-level ...
Mark H. Chin (2314447) +11 more
core +3 more sources
In vivo myocardial superoxide and nitrotyrosine levels. [PDF]
, 2018 Myocardial (A) superoxide was assessed by chemiluminescence, (B) DHE staining and quantitative analysis, (C) nitrotyrosine by ELISA, and (D) nitrotyrosine immunoreactive staining and quantitative analysis from the border zone.
Shinn-Zong Lin (217003) +2 more
core +1 more source
Nitrotyrosine formation with endotoxin-induced kidney injury detected by immunohistochemistry [PDF]
, 1999 The presence of nitrotyrosine in the kidney has been associated with several pathological conditions. In the present study, we investigated nitrotyrosine formation in rat kidney after animals received endotoxin for 24 h.
Karen Davis +4 more
core +1 more source
A schematic drawing to show protein nitrotyrosine. [PDF]
, 2014 A schematic drawing to show protein nitrotyrosine.
Ling-Yun Wu (21548) +5 more
core +1 more source
Investigating protein 3-nitrotyrosine using bioinformatics, biochemistry and chemical derivatisation [PDF]
, 2013 3-nitrotyrosine is a post-translational modification on tyrosine residues detected under a range of pathological conditions. In initial studies this post-translational modification was considered a benign marker of radical oxygen species; however in more
Ng, John Yee Nok
core +2 more sources