Results 51 to 60 of about 18,603 (231)

The Influence of Free 3-Nitrotyrosine and Saliva on the Quantitative Analysis of Protein-Bound 3-Nitrotyrosine in Sputum

open access: yesAnalytical Chemistry Insights, 2007
BackgroundWe have recently developed a new technique for quantitatively measuring protein-bound 3-nitrotyrosine (3-NT), a footprint of nitrosative stress, utilizing high-performance liquid chromatography with an electrochemical detection (HPLC-ECD) system.
Kazuhito, Ueshima   +10 more
openaire   +2 more sources

The role of nitric oxide synthases and nitrotyrosine in retinoblastoma [PDF]

open access: yesCancer, 2005
AbstractBACKGROUNDTo investigate the potential involvement of the nitric oxide (NO) pathway in retinoblastoma, the authors correlated immunoreactivity for endothelial nitric oxide synthase (eNOS), inducible nitric oxide synthase (iNOS), and nitrotyrosine (NT) with the degree of tumor invasiveness in retinoblastoma.METHODSeNOS, iNOS, and NT reactivity ...
Mohan, Adithi   +2 more
openaire   +2 more sources

How developmental stressors affect mitochondrial respiratory function: a systematic review and meta‐analysis

open access: yesBiological Reviews, EarlyView.
ABSTRACT The environmental conditions organisms experience during early development can have powerful and sustained effects on morphology, physiology, behaviour, and performance. Such developmental effects can influence reproductive success, survival, and life‐history strategies and can be transmitted across generations (i.e.
Ondi L. Crino   +7 more
wiley   +1 more source

Superoxide anion and nitrotyrosine staining in aorta. [PDF]

open access: yes, 2012
Quantification of the amplitude of O2–CMH signal (A) and immunohistochemical staining for nitrotyrosine (B-E) in aortae (n = 4–5 for each group).
Sébastien Faure (152623)   +14 more
core   +1 more source

Cellular Membrane‐Targeted Europium(III) Probe for Selective and Time‐Resolved Detection of Peroxynitrite

open access: yesChemistry – A European Journal, EarlyView.
We report a cellular membrane‐targeted europium(III) probe, Eu.Chol, that enables selective, time‐resolved detection of peroxynitrite (ONOO−) at the cell membrane interface. Eu.Chol demonstrates efficient incorporation into liposomes and Jurkat cells, with minimal response to H2O2, establishing a modular platform for subcellular ONOO− sensing ...
Jamie Webb   +6 more
wiley   +1 more source

Distribution of 3-Nitrotyrosine in the nasal polyps of atopic patients. [PDF]

open access: yes, 2004
Objective. To investigate whether formation of nitrotyrosine in the nasal polyps of atopic patients occurs. Study Design. A nonrandomized, retrospective, controlled qualitative and quantitative study. Methods.
Scavuzzo MC   +8 more
core   +1 more source

iNitroY-Deep: Computational Identification of Nitrotyrosine Sites to Supplement Carcinogenesis Studies Using Deep Learning

open access: yesIEEE Access, 2021
In biological systems, Nitration is a crucial post-translational modification which occurs on various amino acids. Nitration of Tyrosine is regarded as nitorsative stress biomarker resulting in the formation of peroxynitrite and other reactive and ...
Sheraz Naseer   +3 more
doaj   +1 more source

Is Nitrotyrosine Generated in Human Erythrocytes in Circulation?

open access: yesBiological and Pharmaceutical Bulletin, 2000
Nitrotyrosine is considered a stable biomarker of reactive nitrogen species, including nitrogen dioxide (NO2) and peroxynitrous acid (ONOOH) in biomaterials. There are inconsistent observations on the detection of free and protein-associated nitrotyrosine in normal human plasma. Human erythrocytes, differentiated from erythrocyte precursor cells in the
KIKUGAWA, Kiyomi   +5 more
openaire   +2 more sources

Quantification of 3-nitrotyrosine in biological tissues and fluids: generating valid results by eliminating artifactual formation [PDF]

open access: yes, 2000
Reactive nitrogen species such as peroxynitrite can nitrate specific amino acids, whether free or protein bound, and 3-nitrotyrosine is believed to be one marker of this reaction.
Smythe, George A   +3 more
core   +1 more source

A modern view on potential biomarkers of Parkinson’s disease (review)

open access: yesPatologìâ, 2020
Parkinson’s disease (PD) is one of the most widespread neurodegenerative diseases. In spite of the large number of researches, the problem of earlier diagnosis and targeted pathogenetic therapy remains relevant.
A. V. Demchenko , V. V. Biriuk
doaj   +1 more source

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