Results 61 to 70 of about 18,603 (231)
Mass Spectrometry Reviews, EarlyView.ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley +1 more source
Pros and cons of current approaches for detecting peroxynitrite and their applications
Biomedical Journal, 2014 Peroxynitrite, a representative of reactive nitrogen species, plays important roles in the physiological and pathological processes of many oxidative stress-related diseases.
Xingmiao Chen +3 more
doaj +1 more source
Andrology, EarlyView.ABSTRACT Background Erectile dysfunction (ED) secondary to cavernous nerve injury (CNI), such as that occurring after radical prostatectomy, remains a significant clinical challenge, particularly among patients who do not respond to phosphodiesterase Type 5 inhibitors (PDE5i).
Minh Nhat Vo +6 more
wiley +1 more source
Nitrotyrosine plaque and myocardial artery score. [PDF]
, 2014 Upper row shows nitrotyrosine staining score of plaque and intramyocardial arteries. Significant differences are marked with the certain significance level. Lower row shows histological examples.
Nicole Arend (529019) +6 more
core +1 more source
Coexpression of NRAMP1, iNOS, and Nitrotyrosine in Bovine Tuberculosis [PDF]
Veterinary Pathology, 2006 In murine models the inducible nitric oxide synthase (iNOS) and the natural resistance associated macrophage protein (NRAMP1) play major roles in host defense against mycobacteria. iNOS regulates nitric oxide (NO) production, which is noxious for ingested mycobacteria, and NRAMP1 displays pleiotropic antimicrobial effects, including upregulation of ...
A L, Pereira-Suárez +4 more
openaire +2 more sources
British Journal of Pharmacology, EarlyView.Background and Purpose The persistence of temporomandibular disorders (TMDs), particularly myogenous, in a person with migraine can lead to exacerbated clinical outcomes and limited response to treatment. The pro‐nociceptive reactive nitroxidative species, peroxynitrite, is involved in migraine mechanisms, but little is known of its role in this ...
Simon Akerman +4 more
wiley +1 more source
Frontiers in Chemistry, 2016 Nitration of tyrosine and other aromatic amino acid residues in proteins occurs in the setting of inflammatory, neurodegenerative and cardiovascular diseases – importantly, this modification has been implicated in the pathogenesis of diverse diseases and
Tal eNuriel +7 more
doaj +1 more source
Neuroimmune alterations and nociceptive behavior in oral carcinogenesis in rats
European Journal of Oral Sciences, EarlyView.Abstract Oral cancer pain is a frequent and debilitating symptom associated with tumor progression. Although neuronal mechanisms have been extensively studied, the role of immune and glial cells in the trigeminal nociceptive pathway remains poorly understood.
Joana Maria dos Santos Alves +7 more
wiley +1 more source
Mitochondrial DNA deletions are associated with upregulated articular nitrotyrosine in human femoral head cartilage [PDF]
, 2016 Background: The pathogenesis of osteoarthritis (OA) has been linked with the elaboration of increased amounts of nitrotyrosine in cartilage as a stable marker of tyrosine nitration by nitric oxide.
Setzer, Bernhard +6 more
core +1 more source
Journal of Diabetes Investigation, EarlyView.Liraglutide combined with Dapagliflozin treatment improves myocardial disease and endothelial dysfunction in T2DM mice. Diabetic cardiomyopathy (DCM) and endothelial dysfunction were established in mice via HFD and STZ injection. The combination therapy of Liraglutide and Dapagliflozin synergistically improved metabolic parameters and attenuated ...
An‐Jun Tan +5 more
wiley +1 more source