Results 81 to 90 of about 18,603 (231)
Semi-quantitative analysis of 3-nitrotyrosine. [PDF]
, 2013 Image of slot-blot film, where 3-nitrotyrosine was detected by immunoblotting and respective surface plot analysis (Y axis represents intensity of bands).
Carla Sousa (242321) +3 more
core +1 more source
MedicinaBackground and Objectives: While depression is associated with an increased risk of Alzheimer’s dementia (AD), traditional AD-related biomarkers, such as amyloid-beta, have shown limited predictive value for late-life depression.
Yoo-Jin Jang +4 more
doaj +1 more source
Plant, Cell &Environment, Volume 49, Issue 8, Page 5849-5865, August 2026.ABSTRACT In this study, we analyzed a unique Nicotiana tabacum BY‐2 line that was gradually adapted to and subsequently maintained in 190 mM NaCl for over 15 years. Years of continuous high salinity shaped a stable “new homeostasis” in BY‐2 suspension cells. Salt‐adapted cells were smaller and formed tighter clusters. Metabolomics revealed constitutive
Anita Rzadkiewicz +8 more
wiley +1 more source
What nitrates tyrosine? Is nitrotyrosine specific as a biomarker of peroxynitrite formation in vivo? [PDF]
, 1997 Peroxynitrite (ONOO−) is a `reactive nitrogen species' that can be formed (among other reactions) by combination of superoxide (O2·−) and nitric oxide (NO·) radicals.
Halliwell, Barry, Barry Halliwell
core +1 more source
Zdorovʹe Rebenka, 2019 Background. In oxidative and nitrosative stresses, the brain is vulnerable to oxidant damage due to high oxygen consumption, large amounts of iron, relatively low antioxidant expression, high concentration of polyunsaturated fatty acids.
G.O. Lezhenko +3 more
doaj +1 more source
iNitro-Tyr: prediction of nitrotyrosine sites in proteins with general pseudo amino acid composition. [PDF]
PLoS ONE, 2014 Nitrotyrosine is one of the post-translational modifications (PTMs) in proteins that occurs when their tyrosine residue is nitrated. Compared with healthy people, a remarkably increased level of nitrotyrosine is detected in those suffering from ...
Yan Xu +5 more
doaj +1 more source
Cancer Medicine, Volume 15, Issue 7, July 2026.ABSTRACT Background and Purpose The treatment of glioblastoma remains a major clinical challenge, largely due to intrinsic and acquired resistance to Temozolomide (TMZ). We aim to advance a novel therapeutic approach to overcome TMZ resistance in human glioblastoma by using the neuronal nitric oxide synthase inhibitor BA‐101 as both a monotherapy and ...
Mallikarjuna Nimgampalle +4 more
wiley +1 more source
Serum lipids and cardiac function correlate with nitrotyrosine and MMP activity in coronary artery disease patients. [PDF]
, 2015 AIMS Peroxynitrite-matrix metalloproteinase (MMP) signalling has been shown to contribute to myocardial ischaemia/reperfusion injury and heart failure and to be influenced by hyperlipidaemia in preclinical models.
Merkely, Béla +23 more
core +1 more source
Immune Dysregulation in Branched Chain Organic Acidemias
Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.ABSTRACT Organic acidemias (OAs) are a group of inherited disorders, most commonly caused by defects in mitochondrial enzymes involved in amino acid and fatty acid metabolism. While they characteristically present with metabolic and neurological crises, growing evidence reveals a significant burden of chronic immune dysregulation in some disorders and ...
Abdul L. Shakerdi +3 more
wiley +1 more source
Analysis of peptides and proteins containing nitrotyrosine by matrix-assisted laser desorption/ionization mass spectrometry [PDF]
, 2001 Oxidative damage to proteins can occur under physiological conditions through the action of reactive oxygen species, including those containing nitrogen such as peroxynitrite (ONO2−).
Gibson, Bradford W +7 more
core +1 more source