Electrochemical behavior of indolone-N-oxides: Relationship to structure and antiplasmodial activity [PDF]
Indolone-N-oxides exert high parasiticidal activity at the nanomolar level in vitro against Plasmodiumfalciparum, the parasite responsible for malaria.
Fabre, Paul-Louis +6 more
core +3 more sources
Regulation of nitric oxide signaling by formation of a distal receptor-ligand complex. [PDF]
The binding of nitric oxide (NO) to the heme cofactor of heme-nitric oxide/oxygen binding (H-NOX) proteins can lead to the dissociation of the heme-ligating histidine residue and yield a five-coordinate nitrosyl complex, an important step for NO ...
Britt, R David +5 more
core +1 more source
Three compounds have been synthesized with formulae [3-MeRad][Ni(dmit)2] (1), [4-MeRad][Ni(dmit)2] (2) and [4-PrRad][Ni(dmit)2] (3) where [Ni(dmit)2]- is an anionic pi-radical (dmit = 1,3-dithiol-2-thione-4,5-dithiolate) and [3-MeRad]+ is 3-N ...
Mauro Cesar Dias +6 more
doaj +1 more source
Conformational Changes in the Metallo-β-lactamase ImiS During the Catalytic Reaction: An EPR Spectrokinetic Study of Co(II)-Spin Label Interactions [PDF]
Metallo-β-lactamases are responsible for conferring antibiotic resistance on certain pathogenic bacteria. In consequence, the search for inhibitors that may be useful in combating antibiotic resistance has fueled much study of the active sites of these ...
Bennett, Brian +3 more
core +2 more sources
Nitroxide-radicals–modified gold nanorods for in vivo CT/MRI-guided photothermal cancer therapy
Luyao Xia,1,2 Chao Zhang,1 Min Li,1 Kaiyu Wang,1 Yushan Wang,1 Peipei Xu,1 Yong Hu2 1Department of Hematology, Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu, 210093, People’s Republic of China; 2College of ...
Xia L +6 more
doaj
Detection of molecular transitions with nitrogen-vacancy centers and electron-spin labels
We present a protocol that detects molecular conformational changes with two nitroxide electron-spin labels and a nitrogen-vacancy (NV) center in diamond.
C. Munuera-Javaloy +4 more
doaj +1 more source
Synthesis And Characterization Of (pyNO−)2GaCl: A Redox-Active Gallium Complex [PDF]
We report the synthesis of a gallium complex incorporating redox-active pyridyl nitroxide ligands. The (pyNO−)2GaCl complex was prepared in 85% yield via a salt metathesis route and was characterized by 1H and 13C NMR spectroscopies, X-ray diffraction ...
Carroll, P. J. +5 more
core +2 more sources
Nuclear spin-lattice relaxation in ferrimagnetic clusters and chains: A contrast between zero and one dimensions [PDF]
Motivated by ferrimagnetic oligonuclear and chain compounds synthesized by Caneschi et al., both of which consist of alternating manganese(II) ions and nitronyl-nitroxide radicals, we calculate the nuclear spin-lattice relaxation rate 1/T_1 employing a ...
A. Caneschi +52 more
core +1 more source
Reaction of endogenous Coenzyme Q10 with nitrogen monoxide and its metabolite nitrogen dioxide
Objectives: Coenzyme Q10, incorporated in DOPC lyposomes or naturally present in liver bovine mitochondria or in human blood plasma, was reacted with nitrogen dioxide •NO2 or with a •NO/•NO2 mixture. Methods and Results: The reaction course was monitored
Paola Astolfi +5 more
doaj +1 more source
Localization of dexamethasone within dendritic core-multishell (CMS) nanoparticles and skin penetration properties studied by multi-frequency electron paramagnetic resonance (EPR) spectroscopy [PDF]
The skin and especially the stratum corneum (SC) act as a barrier and protect epidermal cells and thus the whole body against xenobiotica of the external environment. Topical skin treatment requires an efficient drug delivery system (DDS).
Anske, M. +8 more
core +1 more source

