Systematic monitoring identified a high incidence of hypopituitarism following combined ipilimumab plus nivolumab therapy for metastatic melanoma. [PDF]
Hasan M, Samlowski W, Nakhle S.
europepmc +1 more source
ABSTRACT Introduction Single‐fraction stereotactic radiosurgery (SRS) is recommended for small brain metastases (< 2 cm). However, long‐term outcomes accounting for competing risks—particularly death, which precludes observation of local treatment failure (LTF)—remain limited. Methods We retrospectively analyzed cumulative incidences of LTF, defined as
Isabella Gruber, Oliver Koelbl
wiley +1 more source
Checkpoint Inhibitor-Induced Raynaud's Phenomenon, Hypothyroidism, and Pneumonitis in Head and Neck Cancer: A Case Report. [PDF]
Bodoki L +5 more
europepmc +1 more source
A Phase I/II Study of Ibrutinib Plus Trastuzumab in HER2‐Positive Metastatic Breast Cancer
ABSTRACT Ibrutinib has demonstrated inhibition of ErbB/HER tyrosine kinases in preclinical models. This Phase I/II study investigated the safety, efficacy, and immunomodulatory effects of ibrutinib in combination with trastuzumab in patients with HER2‐positive metastatic breast cancer (MBC) whose disease had progressed on ado‐trastuzumab emtansine ...
Joyce O'Shaughnessy +10 more
wiley +1 more source
A Case of Concurrent Autoimmune Thyroiditis and Adrenal Insufficiency Following Nivolumab Therapy for Advanced Renal Cell Carcinoma. [PDF]
Dooley GD +4 more
europepmc +1 more source
ABSTRACT Background Cabozantinib (CABO) is currently an essential drug for first‐line and sequential therapy in the treatment of advanced renal cell carcinoma (RCC). Predicting its therapeutic efficacy will enable efficient drug selection and improve the prognosis of patients.
Takanari Sakai +10 more
wiley +1 more source
Correction: Combinational therapeutic strategies to overcome resistance to immune checkpoint inhibitors. [PDF]
Alsaafeen BH, Ali BR, Elkord E.
europepmc +1 more source
ABSTRACT Purpose Patients unable to receive cisplatin due to age, comorbidities, or reduced performance status are commonly treated with concurrent radiotherapy (RT) and cetuximab. This study evaluated the prognostic significance of the Geriatric 8 (G8) score and the Charlson Comorbidity Index (CCI) in predicting survival outcomes in this population ...
Esin Kiraz +5 more
wiley +1 more source
Clinical Impact of Nivolumab in Sinonasal Mucosal Melanoma: A 14-Year Single-Center Retrospective Study and Comprehensive Literature Review. [PDF]
Terazawa K +14 more
europepmc +1 more source

