Results 201 to 210 of about 75,992 (272)

Initial Dose Tarlatamab–Associated Tumour Lysis Syndrome in Small Cell Lung Cancer: A Case Report

open access: yesRespirology Case Reports, Volume 14, Issue 7, July 2026.
We report a fatal case of acute TLS following a single 1‐mg dose of tarlatamab in a patient with relapsed SCLC with extensive liver metastases. This case highlights the importance of TLS risk assessment prior to tarlatamab treatment. Extensive liver metastases and elevated lactate dehydrogenase levels may be risk factors for TLS in patients with SCLC ...
Katsuhiko Shibata   +8 more
wiley   +1 more source

Diagnostic Impact of Liver Biopsy Among Antinuclear Antibody Positive Individuals With Mild Liver Enzyme Elevation

open access: yesAlimentary Pharmacology &Therapeutics, Volume 64, Issue 1, Page 103-111, July 2026.
In ANA‐positive patients with suspected autoimmune hepatitis (AIH), liver biopsy rarely altered therapeutic management when alanine aminotransferase (ALT) was below 101 U/L and cirrhosis was absent. These findings suggest that biopsy may be safely deferred in this low‐risk group.
David Mehdi Asgher Niazi   +8 more
wiley   +1 more source

Model‐Informed Development of a Subcutaneous Formulation of Tislelizumab: Phase 1 Pharmacokinetics in Patients With Cancer

open access: yesClinical and Translational Science, Volume 19, Issue 7, July 2026.
ABSTRACT Although tislelizumab is approved across multiple malignancies and dosing schedules, intravenous administration imposes logistical burdens. A subcutaneous formulation may improve convenience and reduce resource demands if comparable exposure is achieved. This study evaluated the pharmacokinetics, bioavailability, and injection‐site performance
Xiangyu Liu   +11 more
wiley   +1 more source

Clinical Impact of Nivolumab in Sinonasal Mucosal Melanoma: A 14-Year Single-Center Retrospective Study and Comprehensive Literature Review. [PDF]

open access: yesCancers (Basel)
Terazawa K   +14 more
europepmc   +1 more source

Mucous Membrane Pemphigoid After Anti‐PD‐1 Therapy: Risk‐Stratified Management and Treatment Outcomes

open access: yesInternational Journal of Dermatology, Volume 65, Issue 7, Page 1376-1382, July 2026.
ABSTRACT Mucous membrane pemphigoid (MMP) following anti‐programmed cell death‐1 (PD‐1) therapy is rare but increasingly reported. Management of high‐ and low‐risk MMP in this setting and the potential oncologic trade‐offs remain poorly defined. We performed a narrative synthesis of all published cases of anti‐PD‐1‐associated MMP, following MEDLINE ...
Serena Dienes   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy