Results 11 to 20 of about 935 (112)

Correlation analysis of IL‐37 gene polymorphisms and susceptibility to chronic HBV infection among Han people in Central China

International Journal of Immunogenetics, Volume 50, Issue 6, Page 299-305, December 2023., 2023
Abstract Hepatitis B virus (HBV) is responsible for various liver diseases, such as chronic hepatitis B (CHB), liver fibrosis, liver cirrhosis (LC) and hepatocellular carcinoma (HCC), which pose a significant threat to human health. An ineffective immune response to HBV can result in viral chronicity.
Hai Cheng, Fenglan Sun, Yaoling Ouyang, Chengbin Li   +3 more
wiley   +1 more source

Antibody response to inactivated COVID‐19 vaccine in patients with type 2 diabetes mellitus after the booster immunization 2型糖尿病患者接种增强剂次灭活COVID‐19疫苗后的抗体反应

Journal of Diabetes, Volume 15, Issue 11, Page 931-943, November 2023., 2023
Highlights Similar antibody response to COVID‐19 inactivated vaccine between healthy controls (HCs) and patients with type 2 diabetes mellitus (T2DM) after a booster shot vaccine within 6 months. Patients with T2DM have reduced antibody response after receiving the third dose of the COVID‐19 vaccine for more than 6 months. Both HCs and T2DM showed poor
Haolong Li, Yao Wang, Xiaomeng Li, Siyu Wang, Xinxin Feng, Xinhua Xiao, Yongzhe Li   +6 more
wiley   +1 more source

Protective effects of nattokinase against microvasculopathy and neuroinflammation in diabetic retinopathy 纳豆激酶对糖尿病视网膜病变微血管病变和神经炎症的保护作用

Journal of Diabetes, Volume 15, Issue 10, Page 866-880, October 2023., 2023
Highlights Nattokinase rescued endothelial dysfunction and pericyte loss in the diabetic retina. Nattokinase attenuated diabetes‐induced retinal inflammation and neurodegeneration. High mobility group box 1 signaling was involved in nattokinase‐mediated retinal protection.
Zijing Huang, Wai Kit Chu, Tsz Kin Ng, Shaolang Chen, Jiajian Liang, Chong‐Bo Chen, Yanxuan Xu, Biyao Xie, Shuping Ke, Qingping Liu, Weiqi Chen, Dingguo Huang   +11 more
wiley   +1 more source

Histopathological characterisation of trunk‐dominant canine pemphigus foliaceus, and comparison with classic facial and insecticide‐triggered forms

Veterinary Dermatology, Volume 34, Issue 5, Page 425-440, October 2023., 2023
Background – While the clinical features were described recently, the histopathological characterisation of trunk‐dominant canine pemphigus foliaceus (PF) is lacking, and whether it differs from classic facial or insecticide‐triggered PF is unknown. Hypothesis/Objectives – This study describes the histopathological findings of trunk‐dominant PF, and ...
Natalie Katharina Yvonne Gedon, Petra Bizikova, Thierry Olivry, Ekaterina Mendoza‐Kuznetsova, Ursula Oberkirchner, James Benjamin Robertson, Keith Emerson Linder   +6 more
wiley   +1 more source

HLA‐DR3 mediated CD4 T cell response against GAD65 in type 1 diabetes patients HLA‐DR3介导的CD4 T细胞对1型糖尿病患者GAD65的应答

Journal of Diabetes, Volume 15, Issue 7, Page 607-621, July 2023., 2023
Highlights The CD4 T cells of type 1 diabetes (T1D) patients particularly having HLA‐DRB1*03‐DQA1*05‐DQB1*02 haplotype are reactive against a particular region of the glutamic acid decarboxylase (GAD65) protein. GAD65 peptides encompassing 288–308 amino acid positions (peptide pool 2) may be favored by the HLA‐DR3 molecule for presentation to CD4 T ...
Neihenuo Chuzho, Neetu Mishra, Nikhil Tandon, Uma Kanga, Gunja Mishra, Akanksha Sharma, Narinder K. Mehra, Neeraj Kumar   +7 more
wiley   +1 more source

COVID‐19 and comorbidities: A role for dipeptidyl peptidase 4 (DPP4) in disease severity? 新冠肺炎与合并症:二肽基肽酶4在疾病严重程度中的作用?

Journal of Diabetes, Volume 12, Issue 9, Page 649-658, September 2020., 2020
Highlights Coronavirus disease 2019 (COVID‐19) is caused by SARS‐CoV‐2; recent modeling of the structure of SARS‐CoV‐2 spike glycoprotein, which mediates viral‐host‐cell entry, predicts interactions with dipeptidyl peptidase 4 (DPP4) in addition to angiotensin‐converting enzyme 2.
Margaret F. Bassendine, Simon H. Bridge, Geoffrey W. McCaughan, Mark D. Gorrell   +3 more
wiley   +1 more source

Programmed Cell Death Ligand 1 in Breast Cancer: Technical Aspects, Prognostic Implications, and Predictive Value

The Oncologist, Volume 24, Issue 11, Page e1055-e1069, November 2019., 2019
Abstract In the light of recent advances in the immunotherapy field for breast cancer (BC) treatment, especially in the triple‐negative subtype, the identification of reliable biomarkers capable of improving patient selection is paramount, because only a portion of patients seem to derive benefit from this appealing treatment strategy. In this context,
Federica Miglietta, Gaia Griguolo, Valentina Guarneri, Maria Vittoria Dieci   +3 more
wiley   +1 more source

Antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID)

Veterinary Dermatology, Volume 36, Issue 3, Page 234-282, June 2025.
Background – Canine pyoderma is one of the most common presentations in small animal practice, frequently leading to antimicrobial prescribing. Objectives – To provide clinicians with antimicrobial treatment guidelines for staphylococcal pyoderma, including those involving meticillin‐resistant staphylococci.
Anette Loeffler, Christine L. Cain, Lluís Ferrer, Koji Nishifuji, Katarina Varjonen, Mark G. Papich, Luca Guardabassi, Siân M. Frosini, Emi N. Barker, J. Scott Weese   +9 more
wiley   +1 more source

Analysis of the immunomodulatory properties of mycobacterium cell wall fraction on the cytokine production of peripheral blood mononuclear cells of healthy dogs

Veterinary Dermatology, Volume 35, Issue 6, Page 595-604, December 2024.
Background – Mycobacterium cell wall fraction (MCWF) is derived from nonpathogenic Mycobacterium phlei and is used as an immunomodulatory compound in clinical practice, yet its mode‐of‐action requires further research. Objective – To evaluate the host response to MCWF in canine peripheral blood mononuclear cells (PBMCs) by using enzyme‐linked ...
Robert Ward, Geoffrey A. Wood, Charlotte Pye, Khalil Karimi, Anthony Yu, Myles St‐Denis, Katherine Blake, Sugandha Raj, Samson Oladokun, Shayan Sharif   +9 more
wiley   +1 more source

Comparison of selected cytomorphological features of canine pemphigus foliaceus and superficial pyoderma

Veterinary Dermatology, Volume 35, Issue 5, Page 524-535, October 2024.
Background – Cytological detection of acantholytic keratinocytes (acantholytic cells [AC]) helps to identify canine pemphigus foliaceus (cPF) yet AC also occurs in superficial pyoderma (SP), the main differential diagnosis. Hypothesis/Objectives – To compare selected cytomorphological features of cPF and SP and to establish cytological diagnostic ...
Tyler S. Spriggs, Natalie K. Y. Gedon, Keith E. Linder, Petra Bizikova   +3 more
wiley   +1 more source