Results 161 to 170 of about 7,196 (266)

The Circulating Cholangiocarcinoma Protein Biomarkers CRP and MASP2 Also Predict Gallbladder Cancer Risk

International Journal of Cancer, Volume 159, Issue 10, Page 2403-2407, 15 November 2026.
ABSTRACT In a recent publication, Lapitz et al. reported differences in serum levels that predict the development of cholangiocarcinoma (CCA) in patients with primary sclerosing cholangitis prior to clinical manifestation. We examined whether these biomarkers also predict the risk of gallbladder cancer (GBC) in European prospective plasma samples from ...
Linda Zollner, Jeroen Krijgsveld, Dominique Scherer, Justo Lorenzo Bermejo, on behalf of the EULAT Eradicate GBC Consortium   +4 more
wiley   +1 more source

Co-Delivery of Fluconazole and Riparin B Using Nanostructured Lipid Carriers: A Quality-by-Design Approach for Enhanced Antifungal Activity. [PDF]

Pharmaceutics
do Nascimento MO, Dias LS, Meneses AKS, Lima SG, Moura CVR, Gutierrez SJC, Barreto HM, do Nascimento DA, Zazeri G, Carvalho ALM.   +9 more
europepmc   +1 more source

Stimuli‐Responsive Lipid‐Based Nanocarriers for Antimicrobial Therapy

Advanced Therapeutics, Volume 9, Issue 11, November 2026.
This manuscript demonstrated, through a scoping review of the literature, that modifying lipid nanocarriers with organic and inorganic excipients is a promising alternative to increase in vitro drug release of antimicrobial compounds under the studied stimulus and significantly enhance in vitro and in vivo antimicrobial activity compared to isolated ...
Brenda Maria Silva Bezerra, Adrian Lima Roberto, Luiz Gustavo Girão Lima, Mariana Rillo Sato, Leila Aparecida Chiavacci, João Augusto Oshiro‐Junior   +5 more
wiley   +1 more source

Juniperus phoenicea extract-loaded nanostructured lipid carriers for potent antimicrobial and anticancer combination therapy. [PDF]

AMB Express
Ismail PA, Elwakil BH, Hagar M, Olama ZA.   +3 more
europepmc   +1 more source

Dual‐Organelle Secretome Conjugation and Organ‐Uptake Tracking (DuO‐SCOUT) Enables Deep and Sensitive Mapping of the Secreted Proteins

Advanced Science, Volume 13, Issue 61, 3 November 2026.
A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang, Rui Qian, Jiaxing Song, Xingqi Meng, Jin Young Kim, Kwok On Lai, Li Wang, Liang Zhang   +7 more
wiley   +1 more source

Development of Imperatorin Nanostructured Lipid Carriers with Grape Seed Oil for Boosting Oral Absorption and Antioxidant Capacity. [PDF]

Molecules
Qiu H, Zhang L, Zhang Y, Zhang C, Wang C, Zhou L, Wang X, Li L, Hou X.   +8 more
europepmc   +1 more source

Curcumin Intervention in Diabetic Neuropathy: Molecular Mechanisms and Preclinical Insights

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
This review highlights curcumin's neuroprotective potential, showing how it mitigates oxidative stress and inflammation by modulating Nrf2, MAPK, and NF‐κB signaling. Preclinical data shows it stabilizes glucose metabolism and reduces nerve degradation.
Sanket Sharma, Rosaline Mishra, Rashmi Singh, Radha Goel, Praveen Kumar Gaur, Kanak Lata   +5 more
wiley   +1 more source

Rutin-Loaded Nanostructured Lipid Carriers Attenuate Doxorubicin-Induced Nephrotoxicity and Modulate Epigenetic Regulation and MyD88/STAT3 Signaling. [PDF]

Toxics
Farag AA, El Gazzar WB, Mostafa M, Mohammed LA, El-Demerdash AS, Ali NEM, Amer RZ, Youssef HS, El-Shaer NO, Mostafa IA, Fakher HM, Soliman S.   +11 more
europepmc   +1 more source

Characterization of Lysosomal Hydrolases and Transporters and Their Age‐Dependent Variability: Relevance to Drug Metabolism and Transport of Small Molecule and Biologic Drugs

Clinical Pharmacology &Therapeutics, Volume 120, Issue 5, Page 1338-1347, November 2026.
Lysosomes play a key role in the accumulation, catabolism, and transport of endogenous and exogenous metabolites and proteins and are involved in drug metabolism and prodrug activation. However, the protein abundance and interindividual variability of lysosomal drug‐metabolizing enzymes and transporters (DMETs) remain underexplored.
Darshak Gadara, Dilip Kumar Singh, Sandhya Subash, Guihua Yue, Deepak Ahire, Chris Bohl, Maciej Czerwinski, Stephanie Helmstetter, Scott Heyward, Robert S. Jones, Cyrus Khojasteh, Ryota Kikuchi, Priyanka Kulkarni, Bin Ma, Bernard Murray, Chris Seib, Bill Smith, David M. Stresser, Mitchell E. Taub, Ting Wang, Bhagwat Prasad   +20 more
wiley   +1 more source

Lymph-Targeted Resveratrol-NLCs Improve Oral Bioavailability: Validation via Rat Mesenteric Lymph Collection System and In Vivo Safety. [PDF]

Animals (Basel)
Zhang X, Shi W, Yang X, Lin Y, Yang B, Deng H, Yu D, Zhou S.   +7 more
europepmc   +1 more source