Results 181 to 190 of about 7,196 (266)

LPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 11, November 2026.
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu, Xiao‐Bo Wan, Yong‐Shun Liang, Tian Lan, Hao Liang   +4 more
wiley   +1 more source

Antibacterial Activity and Safety of Oregano Oil-Lauric Acid Cationic Nanostructured Lipid Carriers in Nile Tilapia (<i>Oreochromis niloticus</i>). [PDF]

Animals (Basel)
Kumanbut R, Kamble MT, Sirimanapong W, Kitiyodom S, Yostawonkul J, Thompson KD, Pirarat N.   +6 more
europepmc   +1 more source

Impact of Dupilumab Therapy on Skin Barrier Function in Patients With Moderate‐to‐Severe Atopic Dermatitis: A Phase IV, Non‐Randomized, Open‐Label, Parallel‐Group Clinical Study

MedComm, Volume 7, Issue 11, November 2026.
This 16‑week study assessed impact of dupilumab on skin barrier function in patients with moderate‑to‑severe atopic dermatitis (AD). Tape‑stripped stratum corneum samples for multi‑omic profiling, alongside transepidermal water loss measurements, were collected from lesional/non‑lesional AD skin and healthy controls at seven time points.
Taoming Liu, Shuting Chen, Weijia Zhao, Dake Di, Jiao Liu, Yuyang Tian, Yurong Luo, Yingping Xu, Ruzeng Xue, Li Ye, Xiaoping Pei, Bihui Yu, Yu Wang, Jiao Zhang, Xiaoling Yu, Wei Wen, Liyan Yuan, Suyun Ji, Claire Hu, Dan Shen, Yiqing Guo, Yunsheng Liang   +21 more
wiley   +1 more source

Mucoadhesive Nanostructured Lipid Carriers of Ketoconazole for Enhanced Dermal Delivery and Antifungal Activity: Formulation Optimization and In Vivo Evaluation. [PDF]

Pharmaceutics
Almutairi M, Youssef AAA, Alsowaida YS, Alobaida A, Ross SA.   +4 more
europepmc   +1 more source

Curcumin in the Treatment of Various Diseases: Mechanism of Action, Bioavailability, Therapeutic Effects, and Current Clinical Trials

MedComm, Volume 7, Issue 11, November 2026.
Curcumin, a naturally occurring polyphenol, exhibits significant anti‐inflammatory and antioxidant capabilities. This review elucidates the specific molecular mechanisms by which curcumin exerts therapeutic effects on various diseases, including neurological disorders, cardiovascular diseases, cancers, inflammatory disorders, and autoimmune diseases ...
Lin Wang, Qifei Pan, Wenjuan Long, Xinyao Li, Jianqin Mao, Sitong Zhou, Zihui Wang, Xuelian Zou, Yuqing She, Mingqin Shi, Yang Zhou, Jiarong Du, Zhongyang Hu, Xiaoman Lv, Yishu Chen, Dongdong Qin   +15 more
wiley   +1 more source

Nanomedicine strategies for overcoming multidrug resistance in breast cancer: recent advances and future perspectives. [PDF]

J Egypt Natl Canc Inst
Kumar M, Tejaswi, Bangwal R, Yadav M, Singh R.   +4 more
europepmc   +1 more source

Identification of Potential Biomarkers for Ulcerative Colitis and Analysis of Immune Cell Infiltration: A Study Based on Data‐Independent Acquisition Proteomics and the GEO Public Database

PROTEOMICS – Clinical Applications, Volume 20, Issue 6, November 2026.
ABSTRACT Background Ulcerative colitis (UC) is a challenging inflammatory bowel disease characterized by chronic inflammation of the colon's mucosal layer. Despite advances in medical research, UC lacks definitive diagnostic tests and targeted treatments.
Shuai Wang, Hualiang Deng, Dajuan Sun
wiley   +1 more source

Nanostructured Lipid Carriers Co-Loaded with Doxycycline, Gentamicin, and Thymol for Enhanced Intracellular Antibacterial Activity Against <i>Brucella melitensis</i>. [PDF]

Int J Nanomedicine
Morovati Moez N, Arabestani MR, Taheri M, Karami P, Alikhani MY, Kazemi S, Hosseini SM.   +6 more
europepmc   +1 more source

Architecting and Industrializing Advanced Production and Manufacturing Systems for Critical Industries

Systems Engineering, Volume 29, Issue 6, Page 1136-1151, November 2026.
ABSTRACT Advanced production systems play a vital role in modern society. Such systems are developed and industrialized over multiple years and at great expense. The complexities of these systems are exacerbated in the case of metal additive manufacturing, which involves numerous process variables and relies on various auxiliary systems.
Duncan W. Gibbons, Andre F. van der Merwe   +1 more
wiley   +1 more source

A Differentiated SH-SY5Y Model of Hypoxic-Ischaemic Injury Reveals Dynamic Transcriptomic Responses During Reoxygenation. [PDF]

Pathophysiology
Salaudeen MA, Allan SM, Pinteaux E.
europepmc   +1 more source