Results 171 to 180 of about 7,196 (266)

Zdhhc14 promotes pyroptosis in the dorsal root ganglion of oxaliplatin‐induced peripheral neuropathy mice by enhancing GBP5 palmitoylation and suppressing its ubiquitination

open access: yesClinical and Translational Medicine, Volume 16, Issue 11, November 2026.
Oxaliplatin‐induced up‐regulation of Zdhhc14 enhances GBP5 stability through palmitoylation‐dependent inhibition of ubiquitin–proteasome degradation, thereby contributing to the development of peripheral neuropathy. Zdhhc14 is identified as a key palmitoyltransferase up‐regulated in oxaliplatin‐induced peripheral neuropathy.
Xiao Jiang   +5 more
wiley   +1 more source

Predicting cardiovascular disease in peritoneal dialysis patients using glycated proteomics and machine learning: A prospective multicentre study

open access: yesClinical and Translational Medicine, Volume 16, Issue 11, November 2026.
Graphical Headlights 1. Glycated proteomics identified candidate cardiovascular biomarkers in peritoneal dialysis patients. 2. A machine learning model integrated two glycated peptides with six clinical indicators. 3. The model achieved ROC‐AUCs of 0.781 in the internal testing set and 0.822 in multicentre external validation.
Ji Ji   +15 more
wiley   +1 more source

Envenomation Leads to Venom Protein Reduction and a Recovery Period in Bumblebee Workers

open access: yesEcology and Evolution, Volume 16, Issue 11, November 2026.
The evolution and deployment of venom systems in social bees have been central to their ecological success, though not without costs. However, for species such as bumblebees, where stinging is not apparently fatal, it raises the question of what, if any, are the consequences associated with venom usage (envenomation).
Safira Moog   +4 more
wiley   +1 more source

Pathogenic Variants in HEPACAM Alter Protein Localization and Interactome in Astrocytes of the Developing Mouse Cortex

open access: yesGlia, Volume 74, Issue 11, November 2026.
Pathogenic variants alter hepaCAM protein distribution. Astrocyte‐specific hepaCAM TurboID reveals KCNQ2 as a new interaction partner. Pathogenic variants alter hepaCAM association with key transmembrane proteins. ABSTRACT Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare leukodystrophy characterized by early‐onset macrocephaly,
Robert W. Lewis   +10 more
wiley   +1 more source

Energy Balance-Related Factors and Direct Tumor-Adipocyte Contact in Colorectal Cancer: Etiologic Insights from the Population-Based Netherlands Cohort Study. [PDF]

open access: yesCancer Epidemiol Biomarkers Prev
Offermans K   +7 more
europepmc   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

open access: yesJSFA reports, Volume 6, Issue 11, Page 473-489, November 2026.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz   +10 more
wiley   +1 more source

The Impact of Surfactants in Tailoring Nanostructured Lipid Carriers for Inhaled Levofloxacin. [PDF]

open access: yesACS Omega
Beraldo de Araujo VL   +8 more
europepmc   +1 more source

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