Results 71 to 80 of about 7,196 (266)
Polynomial models for the right NLCs of six subjects selected at random.
, 2016 Polynomial models for the right NLCs of six subjects selected at random.
Lucia Jañez-Garcia (3169641) +5 more
core +1 more source
Overcoming biological barriers BBB/BBTB by designing PUFA functionalised lipid-based nanocarriers for glioblastoma targeted therapy [PDF]
, 2023 A major obstacle for chemotherapeutics in Glioblastoma (GB) is to reach the tumour cells due to the presence of the blood-brain barrier (BBB) and chemoresistance of anticancer drugs.
Zwain, Tamara +8 more
core +1 more source
Advanced Science, EarlyView.In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang +18 more
wiley +1 more source
, 2019 Here we report the development of tristearin-based nanostructured-lipid carriers (NLCs) which were further surface-modified with mucoadhesive N,N,N-trimethyl chitosan (TMC) to form mucoadhesive nanostructured-lipid carriers (mNLCs).
Veena S Belgamwar (7512098) +1 more
core +1 more source
Advanced Science, EarlyView.This study reveals that during skeletal aging, bone marrow adipocyte‐derived sDPP4 primes STING signaling in macrophages. In combination with mitochondrial DNA, this signaling activates CD38 and depletes local NAD+/NMN, thereby impairing osteogenesis.
Zhichao Li +12 more
wiley +1 more source
Drug Design, Development and Therapy, 2022 Min Du,1 Jianbo Yin2 1Department of Pharmacy, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu Province, 214000, People’s Republic of China; 2Department of Pharmacy, Wuxi Dashan Medical Beauty Clinic, Wuxi, Jiangsu Province, 214001, People’s ...
Du M, Yin J
doaj
A comparison of the accuracy of iTRAQ quantification by nLC-ESI MSMS and nLC-MALDI MSMS methods
Journal of Proteomics, 2010 The accuracy of quantification obtained using the iTRAQ labelling methodology for measuring protein ratios more extreme than 1:1 was investigated. A comparison of nLC-ESI MSMS and nLC-MALDI MSMS analysis routes was performed. A fixed concentration of a standard six protein mix was spiked with two proteins at a range of concentrations.
Shirran, Sally L., Botting, Catherine H.
openaire +2 more sources
Advanced Science, EarlyView.A novel geometry‐resolved membrane platform provides a seamlessly integrated pipeline for studying curvature‐sensing proteins. By linking shotgun proteomics with quantitative imaging, this approach enables both the unbiased discovery and rigorous validation of novel sensors across the entire curvature range—positive, negative, and zero.
Takumi Komikawa +6 more
wiley +1 more source
AnomalousZ′ effects in the WW channel at NLC [PDF]
Zeitschrift für Physik C: Particles and Fields, 1996 We consider the virtual signals of a $Z'$ of very general type in the process $e^+e^-\to W^+W^-$ at a future linear collider (NLC). We show that possible deviations from the SM predictions in this channel are related to similar deviations in the purely leptonic one in a way that is only characteristic of this $Z'$ model, and not in general of possible ...
Chiappetta, P. +2 more
openaire +2 more sources
SAV1 in Cooperation With FKBP52 Participates in Implantation
Advanced Science, EarlyView.The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao +10 more
wiley +1 more source