Results 101 to 110 of about 300,840 (336)

Structural basis of NLR activation and innate immune signalling in plants

Immunogenetics, 2022
Animals and plants have NLRs (nucleotide-binding leucine-rich repeat receptors) that recognize the presence of pathogens and initiate innate immune responses.
Natsumi Maruta, H. Burdett, B. Lim, Xiahao Hu, Sneha Desa, M. K. Manik, B. Kobe   +6 more
semanticscholar   +1 more source

The NLR Gene Family: A Standard Nomenclature [PDF]

Immunity, 2008
Iimmune regulatory proteins such as CIITA, NAIP, IPAF, NOD1, NOD2, NALP1, cryopyrin/NALP3 are members of a family characterized by the presence of a nucleotide-binding domain (NBD) and leucine-rich repeats (LRR). Members of this gene family encode a protein structure similar to the NB-LRR subgroup of disease-resistance genes in plants and are involved ...
Ting, Jenny P.-Y., Lovering, Ruth C., Alnemri, Emad S., Bertin, John, Boss, Jeremy M., Davis, Beckley K., Flavell, Richard A., Girardin, Stephen E., Godzik, Adam, Harton, Jonathan A., Hoffman, Hal M., Hugot, Jean-Pierre, Inohara, Naohiro, Mackenzie, Alex, Maltais, Lois J., Nunez, Gabriel, Ogura, Yasunori, Otten, Luc A., Philpott, Dana, Reed, John C., Reith, Walter, Schreiber, Stefan, Steimle, Viktor, Ward, Peter A.   +23 more
openaire   +4 more sources

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Dusty Structure Around Type-I Active Galactic Nuclei: Clumpy Torus Narrow Line Region and Near-Nucleus Hot Dust [PDF]

, 2009
We fitted Spitzer/IRS ~2-35 um spectra of 26 luminous QSOs in attempt to define the main emission components. Our model has three major components: a clumpy torus, dusty narrow line region (NLR) clouds and a blackbody-like dust.
Abazajian, Antonucci, Bennert, Bock, Draine, Efstathiou, Elitzur, Gavazzi, Glikman, Granato, Grasdalen, Guyon, Guyon, Hagai Netzer, Hyland, Imanishi, Jarrett, Jarrett, Lauer, Lawrence, Mason, Matsuoka, Mentuch, Minezaki, Moshe Elitzur, Nenkova, Nenkova, Nenkova, Netzer, Netzer, Netzer, Netzer, Netzer, Netzer, Ossenkopf, Packham, Radomski, Richards, Riffel, Rivay Mor, Rowan-Robinson, Schmitt, Schweitzer, Schweitzer, Scoville, Sirocky, Soifer, Sturm, Sturm, Suganuma, Surace, Surace, Teplitz, Thompson, Tomono, Treister, Treister, Veilleux, Wang, York   +59 more
core   +3 more sources

Assembly and Architecture of NLR Resistosomes and Inflammasomes.

Annual Review of Biophysics, 2022
Nucleotide-binding and leucine-rich repeat (NLR) proteins are critical intracellular immune receptors in both animals and plants. Perception of pathogen-derived or stress-associated signals induces NLR oligomerization to form multiprotein complexes ...
Zehan Hu, J. Chai
semanticscholar   +1 more source

Integrated Single‐Cell and Spatial Transcriptomics Reveal Cell‐Type‐Specific Immune Regulatory Networks in Maize Responding to Southern Corn Rust

Advanced Science, EarlyView.
By integrating single‐nuclei and spatial transcriptomics, this study presents a stereoscopic landscape of maize leaf to Puccinia polysora infection. Epidermal and mesophyll cells initiate primary defenses via RLPs/RLKs and jasmonic acid signaling. Cell‐cell communication analyses further reveal the underlying the dynamics of the underlying immune ...
Qiongqiong Wang, Xinyan Sun, Yingchao Sun, Zeqiang Cheng, Zixiang Cheng, Shengbo Han, Ying Feng, Wenbo Yang, Huimin Li, Meichen Zhu, Xiaoling Wu, Jinghua Zhang, Jihua Tang, Honglian Li, Yanyong Cao, Canxing Duan, Yan Shi   +16 more
wiley   +1 more source

Mild COVID-19 infection-predicting symptomatic phase and outcome: A study from AIIMS, New Delhi

Journal of Family Medicine and Primary Care, 2020
Context: Comprehensive management of mild COVID infection calls for better understanding of symptomatology in these group of patients as well as early identification and close monitoring of patients at risk, data on which is limited.
J Kirtana, Arvind Kumar, Swasthi S Kumar, Anupam K Singh, Sujay Halkur Shankar, Amrit Sharma, Amit Kumar, Ravneet Kaur, Maroof A Khan, Piyush Ranjan, Prayas Sethi, Avinash Chakravarthy, Achal K Srivastava, Naveet Wig   +13 more
doaj   +1 more source

Factors Associated with Length of Stay of COVID-19 Patients at Serui Regional General Hospital Papua Province: Cross-Sectional Study

Jurnal Penyakit Dalam Indonesia, 2021
Introduction. Coronavirus Disease 2019 (COVID-19) is a respiratory infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2 has become a global health problem.
Fahri Ahmad Baihaqi, Henny Rumaropen
doaj   +1 more source

The Intermediate Line Region in AGN: a region "praeter necessitatem"?

, 1999
As a consequence of improved S/N, spectral resolution and wavelength coverage various authors have introduced, without strong justification, new emitting regions to account for various emission line profile differences in AGN. The so-called CIVlambda1549
Marziani, P., Sulentic, J. W.
core   +1 more source

Show me your ID: NLR immune receptors with integrated domains in plants

Essays in Biochemistry, 2022
Nucleotide-binding and leucine-rich repeat receptors (NLRs) are intracellular plant immune receptors that recognize pathogen effectors secreted into the plant cell.
Clémence Marchal, Vassiliki A. Michalopoulou, Z. Zou, V. Çevik, P. Sarris   +4 more
semanticscholar   +1 more source