Results 181 to 190 of about 300,840 (336)

Pattern-recognition receptors are required for NLR-mediated plant immunity

open access: yesNature, 2020
Minhang Yuan   +9 more
semanticscholar   +1 more source

Predicting Different Recurrence Risk in HNSCC Using Circulating Inflammatory and T‐Cell Biomarkers

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Objective Head and neck squamous cell carcinoma (HNSCC) lacks reliable prognostic circulating biomarkers, and the role of the immune system in its progression remains incompletely understood. This study aimed to evaluate the prognostic value of systemic inflammatory and immune biomarkers in surgically treated patients with primary oral cavity (
Riccardo Gili   +10 more
wiley   +1 more source

Evaluation of Systemic Inflammatory Markers in Predicting Malignancy in Parotid Gland Tumors

open access: yesThe Laryngoscope, EarlyView.
Preoperative systemic inflammatory indices may assist in distinguishing benign from malignant parotid tumors. In this cohort of 259 patients undergoing parotidectomy, malignant tumors were associated with higher neutrophil‐to‐lymphocyte ratio (NLR) and platelet‐to‐lymphocyte ratio (PLR) values, as well as larger tumor size and older age.
Ozcelik Erdem Rukiye   +3 more
wiley   +1 more source

Time and Energy Managed Operations (TEMO): Cessna Citation II Flight Trials [PDF]

open access: yes, 2016
From 9-26 October 2015 the Netherlands Aerospace Centre (NLR) in cooperation with Delft University of Technology (DUT) has executed Clean Sky flight trials with the Cessna Citation II research aircraft.
Bussink, Frank   +3 more
core  

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

open access: yesMed Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang   +22 more
wiley   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

open access: yesMed Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang   +12 more
wiley   +1 more source

Prediction and Prognostication of Peripheral Blood Biomarkers in Head and Neck Cutaneous Squamous Cell Carcinoma

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective While many with head and neck cutaneous squamous cell carcinomas (cHNSCC) respond well to surgery alone, there is a need to refine traditional staging systems. We aim to identify whether peripheral blood biomarkers (PBBMs) may enhance current staging for prognostication and adjuvant treatment selection.
Mikayla G. Hubbard   +7 more
wiley   +1 more source

The Significance of Neutrophil-to-Lymphocyte Ratio and Combined Chemoradiotherapy in Patients Undergoing Bladder Preservation Therapy for Muscle-Invasive Bladder Cancer

open access: yesCancer Management and Research, 2020
Chun-Te Wu,1,2 Yun-Ching Huang,2,3 Wen-Cheng Chen,2,4 Miao-Fen Chen2,4 1Department of Urology, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan; 2Chang Gung University, College of Medicine, Taoyuan, Taiwan; 3Department of Urology, Chang Gung ...
Wu CT, Huang YC, Chen WC, Chen MF
doaj  

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan   +5 more
wiley   +1 more source

Carbon Performance in Airlines: A Qualitative Comparative Analysis of Institutional and Firm‐Level Drivers

open access: yesSustainable Development, EarlyView.
ABSTRACT Air transport is one of the fastest‐growing sources of greenhouse gas emissions, yet it remains one of the most difficult sectors to decarbonize. The sector's climate impact is amplified by two factors: the steady rise in passenger demand and the absence of commercially viable low‐carbon technologies for long‐haul flights.
Jouni K. Juntunen   +2 more
wiley   +1 more source

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