Results 201 to 210 of about 229,010 (267)

Estimated pulse wave velocity as a marker of major adverse cardiovascular events in essential thrombocythaemia and polycythaemia vera

British Journal of Haematology, EarlyView.
In patients with essential thrombocythaemia or polycythaemia vera, higher estimated pulse wave velocity (ePWV) was independently associated with major adverse cardiovascular events, while its relationship with overall survival was largely age‐driven.
Alessandro Costa, Olga Mulas, Federica Pilo, Eleonora Atzeni, Martina Pettinau, Daniela Mantovani, Giovanni Caocci   +6 more
wiley   +1 more source

Pleiotropic Roles of FBXO11 in Tumorigenesis: Implications for Targeted Therapy

Cancer Science, EarlyView.
This complex comprises of scaffold CUL1, SKP1, RBX1 and FBXO11 receptor. The substrate is phosphorylated by specific kinase enzyme and recognized by the substrate recognition domain. FBXO11 targets numerous substrates for ubiquitination and degradation, FBXO11 substrates mainly include Snail, ZEB1, p53, BCL6, CDT2, CIITA, Cdc25a, hnRNPA2B1, SAMD1 and ...
Yuqi Zhang, Changyi Fan, Shiheng Chen, Tianyue Lu, Yuanyuan Li, Feng Du, Shanshan Wang   +6 more
wiley   +1 more source

Lung Cancer Brain Metastasis: Brain Microenvironmental Adaptation, Therapeutic Resistance and Translational Strategies

Cancer Science, EarlyView.
Lung cancer brain metastasis is shaped by dynamic crosstalk among tumor cells, the blood–brain barrier, glial and immune cells, neurons, and metabolic niches. This review integrates these mechanisms with therapeutic resistance, translational models, CNS delivery, and multidisciplinary treatment strategies.
Jun Yang, Junyi Xiong, Li Ying, Yanyang Zeng, Ziqiang Ouyang, Mei Liu, Meihua Li   +6 more
wiley   +1 more source

Dynamic neutrophil-to-lymphocyte ratio as an independent prognostic marker of overall survival in patients receiving immune checkpoint inhibitors: a Latin American cohort study. [PDF]

Front Oncol
Chatterjee P, Insagaray B, Ferraz T, González M, Muñoz G, Pombo V, Barrios R, Cuello M.   +7 more
europepmc   +1 more source

Limitations of PIV Biomarker Analysis Related to Chemoradiotherapy and Unadjusted Confounders

Cancer Science, EarlyView.
The pan‐immune‐inflammation value (PIV) derived from four blood cell counts warrants cautious interpretation in rectal‐cancer immunotherapy, as CRT cannot be disentangled from anti‐PD‐1 effects within the small n = 16 subgroup.
Hongbo Gao, Wencai Weng
wiley   +1 more source

Inflammatory Hematological Indices in Heart Failure with Preserved Ejection Fraction: Associations with Disease Severity and 12-Month Outcomes. [PDF]

Biomedicines
Maghet C, Arnăutu DA, Arnautu SF, Buz BF, Tomescu MC, Olariu TR.   +5 more
europepmc   +1 more source

Efficient and accurate implementation of the k-omega turbulence model in the NLR multi-block Navier-Stokes system

, 2000
Spekreijse, S.P., Kok, J.C.
core  

Diagnostic Performance of cfDNA‐Based Liquid Biopsy for Hepatocellular Carcinoma: A Systematic Review and Meta‐Analysis

Cancer Science, EarlyView.
This meta‐analysis demonstrates high diagnostic accuracy of cfDNA‐based liquid biopsy for HCC, with stage‐ and assay‐dependent performance and substantial inter‐study heterogeneity. ABSTRACT Conventional surveillance tools for hepatocellular carcinoma (HCC) have limited sensitivity.
Jiwei Liu, Yangyu Zhang, Shuo Yang, Yanhua Wu, Jing Jiang   +4 more
wiley   +1 more source