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NLRs in plants

Current Opinion in Immunology, 2015
Intracellular immune receptors with nucleotide-binding, leucine-rich domains (NLRs) are found in both plants and animals. Compared to animals, NLR-encoding gene families are expanded, more prevalent and have enriched diversity in higher plants. Strong host defense triggered by the recognition of specific pathogen effectors constitutes a major part of ...
Xin Li, Paul Kapos, Yuelin Zhang
openaire   +2 more sources

Evolution and Conservation of Plant NLR Functions [PDF]

open access: yesFrontiers in Immunology, 2013
In plants and animals, nucleotide-binding domain and leucine-rich repeats (NLR)-containing proteins play pivotal roles in innate immunity. Despite their similar biological functions and protein architecture, comparative genome-wide analyses of NLRs and genes encoding NLR-like proteins suggest that plant and animal NLRs have independently arisen in ...
Florence Jacob, Takaki Maekawa
exaly   +8 more sources

Method to Measure Ubiquitination of NLRs

2023
Posttranslational modifications are crucial in determining the functions of proteins in the cell. Modification of the NLRP3 inflammasome by the ubiquitin system has recently emerged as a new level of regulation of the inflammasome complex. Here we describe a method to detect poly-ubiquitination of NRLP3 using two different approaches: (i) detection ...
Worboys, Jonathan D; id_orcid 0000-0002-8242-4901   +2 more
openaire   +3 more sources

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