Results 221 to 230 of about 229,010 (267)

A guide to host genetic determinants of female microbiome composition across distinct anatomical niches

The FEBS Journal, EarlyView.
Host genetic variation in immune regulation and cell signalling genes was associated with microbiome composition across vaginal, gut, oral and skin sites, while associations involving metabolic function, epithelial barrier integrity and hormonal processes were more site‐specific. Overall, our findings indicate that host genetic variation contributes to
Isabella Margaret Davidson, Elham Nikbakht, Hayley O'Neill, Larisa Margaret Haupt, Paul Joseph Dunn   +4 more
wiley   +1 more source

The merits of the prognostic nutritional index and neutrophil-to-lymphocyte ratio in predicting outcomes of coronary artery bypass grafting: a retrospective cohort study. [PDF]

BMC Cardiovasc Disord
Elgazzar MA, Hani BM, Ali AF, Elshafie MA, Elnahas AM.   +4 more
europepmc   +1 more source

Clinical Outcomes of Gradual Corticosteroid Tapering for Immune Checkpoint Inhibitor‐Induced Liver Injury

Hepatology Research, EarlyView.
Patients with severe ICI‐induced liver injury are commonly treated with corticosteroids, but the optimal tapering strategy remains uncertain. In this study, a gradual corticosteroid tapering strategy based partly on Japanese clinical practice for autoimmune hepatitis was associated with a low rate of relapse and enabled many patients to safely resume ...
Naoto Soma, Yoshihito Uchida, Kayoko Sugawara, Masamitsu Nakao, Nobuaki Nakayama, Yukinori Imai, Suguru Mizuno, Satoshi Mochida   +7 more
wiley   +1 more source

Development and Internal Validation of the BRICS Score: A Preoperative Clinical and Hematological Model for Predicting High-Grade and Muscle-Invasive Bladder Cancer. [PDF]

Cancers (Basel)
Gherasim RD, Porav-Hodade D, Chibelean C, Voidazan S, Todea-Moga C, Vida OA, Ghirca VM, Vascul RF, Reman TL, Martha OKI.   +9 more
europepmc   +1 more source

Longitudinal changes in readily available inflammatory markers before and after switching to integrase inhibitor‐based antiretroviral therapy in Virologically suppressed people living with HIV: A Nationwide real‐world cohort study

HIV Medicine, EarlyView.
Abstract Background Persistent immune activation and systemic inflammation remain key features of chronic HIV infection despite sustained virological suppression under antiretroviral therapy (ART), contributing to excess non‐AIDS morbidity and mortality.
Stelios Assimakopoulos, Achilleas Stamoulopoulos, Mina Psichogiou, Varvara Vasalou, Vasileios Papastamopoulos, Antonis Papadopoulos, Georgios Adamis, Maria Chini, Simeon Metallidis, Georgios Loizos, Lydia Leonidou, Helen Sambatakou, Markos Marangos, Diamantis Kofteridis, Giota Touloumi, on behalf of AMACS, G. Adamis, M. Chini, G. Chrysos, M. Marangos, O. Katsarou, D. Kofteridis, S. Metallidis, P. Panagopoulos, N. Pantazis, A. Papadopoulos, V. Paprizos, V. Papastamopoulos, M. Psichogiou, H. Sambatakou, NV. Sipsas, G. Touloumi, G. Touloumi, N. Pantazis, C. Thomadakis, A Stamoulopoulos, A Papadopoulos, A Antoniadou, C Protopapas, D Kavatha, G Chrysos, T Nitsotolis, M Psichogiou, E Mastrogianni, G Adamis, M Astriti, MN Marangos, L Leonidou, O Katsarou, A Kouramba, NV Sipsas, A Kontos, D Basoulis, M Chini, G Tsekes, N Mangafas, S Metallidis, O Tsachouridou, Τ Chrysanthidis, V Paparizos, V Vasalou, S Kourkounti, H Sambatakou, V Papastamopoulos, G Lourida, P Panagopoulos, V Petrakis, D Kofteridis, K Alexakis, V Malikidis, H Gogos, M Psichogiou   +71 more
wiley   +1 more source

Association between systemic inflammation and long-term mortality in emergency department patients with severe hypertension. [PDF]

Clinics (Sao Paulo)
Yoo B, Kim BS, Kim HJ, Shin JH.
europepmc   +1 more source

Dental Flossing and Oral Health Outcomes in Adults Over A 10‐Year Period: A Cohort Study

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Objective To analyse the effect of flossing on dental caries and periodontal conditions in adults from Sobral, Ceará, Brazil over 10 years. Methods This was a prospective cohort. The sample was 260 adults (aged 27–31) who participated in 2012 and 2022 follow‐ups.
Icaro Santiago de Aquino, Adriano de Aguiar Filgueira, Mariana Ramalho de Farias, Rodrigo Otavio Rego, Luiz Roberto Augusto Noro, Ana Karine Macedo Teixeira   +5 more
wiley   +1 more source

Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy

Immunology &Cell Biology, EarlyView.
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley   +1 more source