The primary function of statins is to inhibit cholesterol synthesis, which contributes to their antidiabetic effects. However, the majority of the diabetic effects of statins are due to inhibition of isoprenoid synthesis. Atorvastatin, simvastatin and rosuvastatin possess the most pronounced diabetogenic properties. In contrast, lovastatin, fluvastatin,
Ali Nosrati Andevari, Mohsen Koolivand
wiley +1 more source
Inflammatory Factors in Allergic Rhinitis: A 20‐Year Bibliometric Mapping and Emerging Trends
This figure illustrates the bibliometric process and results of research on inflammatory factors of allergic rhinitis from 2004 to 2024 including data screening, global distribution, collaborative networks and the evolution of research hotspots. ABSTRACT Allergic rhinitis (AR) is driven by a network of inflammatory mediators released by mast cells ...
Shanshan Jing, Fengying Zhang, Qiqi Liu
wiley +1 more source
Are Inflammatory Biomarkers at ICU Discharge Still Predictive of Post-ICU Mortality in Sepsis and Septic Shock? A Retrospective, Single-Center Cohort Study. [PDF]
Ay M, Sari R.
europepmc +1 more source
ABSTRACT Objective To provide a comprehensive review of the biological rationale, clinical evidence, and practical perioperative management of immunotherapy for the head and neck surgeon. Summary Background Data Standard treatment for resectable head and neck squamous cell carcinoma (HNSCC) has reached a survival plateau, with over 50% of patients ...
Nicholas Brian Shannon, Bruce Ashford
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Systemic inflammatory ratios and their added value to cytology in cervical cancer detection: a multicenter study. [PDF]
Vajda G +9 more
europepmc +1 more source
Evaluation of Systemic Inflammatory Markers in Predicting Malignancy in Parotid Gland Tumors
Preoperative systemic inflammatory indices may assist in distinguishing benign from malignant parotid tumors. In this cohort of 259 patients undergoing parotidectomy, malignant tumors were associated with higher neutrophil‐to‐lymphocyte ratio (NLR) and platelet‐to‐lymphocyte ratio (PLR) values, as well as larger tumor size and older age.
Ozcelik Erdem Rukiye +3 more
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Association of Dynamic Changes in the Neutrophil-to-Lymphocyte Ratio with Mortality in Patients on Maintenance Hemodialysis: A Retrospective Cohort Study. [PDF]
Ergun G.
europepmc +1 more source
Digital Phenotyping of Physical Activity and Mortality in Cancer Survivors
The study analyzed wrist‐worn accelerometer data from 864 cancer survivors in the NHANES dataset (left panel). We identified three key digital phenotypes and their optimal thresholds for survival benefit: MIMS Volume (> 4945), Intensity (> 24), and Variability (> 2.4) (middle panel).
Yuanyou Li +5 more
wiley +1 more source
The neutrophil-to-lymphocyte ratio predicts all-cause and cardiovascular mortality in patients with nonalcoholic fatty liver disease: Evidence from the National Health and Nutrition Examination Survey 1999 to 2018. [PDF]
Du Z, Jiang J, Lv X, Hou Y, Li D.
europepmc +1 more source

