Results 11 to 20 of about 300,840 (336)
Diverse NLR immune receptors activate defence via the RPW8-NLR NRG1. [PDF]
New Phytologist, 2019 Most land plant genomes carry genes that encode RPW8-NLR Resistance (R) proteins. Angiosperms carry two RPW8-NLR subclasses: ADR1 and NRG1. ADR1s act as 'helper' NLRs for multiple TIR- and CC-NLR R proteins in Arabidopsis. In angiosperm families, NRG1 co-
Baptiste Castel +7 more
semanticscholar +5 more sources
NLR-parser: rapid annotation of plant NLR complements [PDF]
Bioinformatics, 2015 Abstract Motivation: The repetitive nature of plant disease resistance genes encoding for nucleotide-binding leucine-rich repeat (NLR) proteins hampers their prediction with standard gene annotation software. Motif alignment and search tool (MAST) has previously been reported as a tool to support annotation of NLR-encoding genes. However,
Steuernagel, Burkhard +4 more
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Animal NLRs provide structural insights into plant NLR function [PDF]
Annals of Botany, 2016 The plant immune system employs intracellular NLRs (nucleotide binding [NB], leucine-rich repeat [LRR]/nucleotide-binding oligomerization domain [NOD]-like receptors) to detect effector proteins secreted into the plant cell by potential pathogens.
Bentham, Adam +4 more
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NLR, d-NLR and PLR can be affected by many factors
International Immunopharmacology, 2021 We have read the article by Yang et al, entitled "The diagnostic and predictive role of NLR, d-NLR and PLR in COVID-19 patients" with great interest. The authors emphasized that the NLR (Neutrophil to lymphocyte ratio) is an independent prognostic biomarker for COVID-19 patients. First of all, we congratulate the authors for their valuable contribution
Bedel, Cihan +2 more
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New Phytologist, 2022 SummaryPlant intracellular nucleotide‐binding leucine‐rich repeat immune receptors (NLRs) perceive the activity of pathogen‐secreted effector molecules that, when undetected, promote colonisation of hosts. Signalling from activated NLRs converges with and potentiates downstream responses from activated pattern recognition receptors (PRRs) that sense ...
Daniel Lüdke +3 more
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Animal NLRs continue to inform plant NLR structure and function [PDF]
Archives of Biochemistry and Biophysics, 2019 Plant NLRs share many of the structural hallmarks of their animal counterparts. At a functional level, the central nucleotide-binding pocket appears to have binding and hydrolysis activities, similar to that of animal NLRs. The TIR domains of plant NLRs have been shown to self-associate, and there is emerging evidence that full-length plant NLRs may do
Burdett, Hayden +2 more
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NLR receptor networks in plants
Essays in Biochemistry, 2022 Abstract To fight off diverse pathogens and pests, the plant immune system must recognize these invaders; however, as plant immune receptors evolve to recognize a pathogen, the pathogen often evolves to escape this recognition. Plant–pathogen co-evolution has led to the vast expansion of a family of intracellular immune receptors ...
Adachi, Hiroaki, Kamoun, Sophien
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Unsolved Mysteries in NLR Biology [PDF]
Frontiers in Immunology, 2013 NOD-like receptors (NLRs) are a class of cytoplasmic pattern-recognition receptors. Although most NLRs play some role in immunity, their functions range from regulating antigen presentation (NLRC5, CIITA) to pathogen/damage sensing (NLRP1, NLRP3, NLRC1/2, NLRC4) to suppression or modulation of inflammation (NLRC3, NLRP6, NLRP12, NLRX1). However, NLRP2,
Lupfer, Christopher +1 more
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NLR signaling in plants: from resistosomes to second messengers.
TIBS -Trends in Biochemical Sciences. Regular ed, 2023 Nucleotide binding and leucine-rich repeat-containing receptors (NLRs) have a critical role in plant immunity through direct or indirect recognition of pathogen effectors.
Shijia Huang +6 more
semanticscholar +1 more source
Cambridge Prisms: Global Mental Health, 2020 Leprosy has long-term consequences related to impairment and stigma. This includes a major impact on mental health. This study aims to consolidate current evidence regarding the mental health impact of leprosy on affected persons and their family members.
PMW Somar, MM Waltz, WH van Brakel
doaj +1 more source