Results 31 to 40 of about 192,001 (267)

The diagnostic and predictive role of NLR, d-NLR and PLR in COVID-19 patients

International Immunopharmacology, 2020
To accumulate evidence that indicated the key role played by virus-triggered inflammation in the 2019-novel coronavirus disease (COVID-19) which emerged in Wuhan City and rapidly spread throughout China.Age, neutrophil(NEU)-to-lymphocyte (LYM) ratio (NLR), lymphocyte-to-monocyte (MON) ratio, platelet-to-lymphocyte ratio (PLR), and C-reactive protein ...
Yang, Ai-Ping, Liu, Jian-ping, Tao, Wen-qiang, Li, Hui-ming   +3 more
openaire   +2 more sources

Topology Optimization for Aircraft Applications Using Hybrid and Multi-Material Methods for Different Component Scales

Engineering Proceedings
The aviation industry, responsible for a significant portion of global CO2 emissions, faces the need to transition to more sustainable aircraft. Electric aircraft driven by battery-powered propulsion and further structural weight reductions have emerged ...
Wouter van den Brink, Tim Koenis, Timo Osinga, Maria Montero-Sistiaga   +3 more
doaj   +1 more source

The NLR Gene Family: A Standard Nomenclature [PDF]

Immunity, 2008
Iimmune regulatory proteins such as CIITA, NAIP, IPAF, NOD1, NOD2, NALP1, cryopyrin/NALP3 are members of a family characterized by the presence of a nucleotide-binding domain (NBD) and leucine-rich repeats (LRR). Members of this gene family encode a protein structure similar to the NB-LRR subgroup of disease-resistance genes in plants and are involved ...
Ting, Jenny P.-Y., Lovering, Ruth C., Alnemri, Emad S., Bertin, John, Boss, Jeremy M., Davis, Beckley K., Flavell, Richard A., Girardin, Stephen E., Godzik, Adam, Harton, Jonathan A., Hoffman, Hal M., Hugot, Jean-Pierre, Inohara, Naohiro, Mackenzie, Alex, Maltais, Lois J., Nunez, Gabriel, Ogura, Yasunori, Otten, Luc A., Philpott, Dana, Reed, John C., Reith, Walter, Schreiber, Stefan, Steimle, Viktor, Ward, Peter A.   +23 more
openaire   +3 more sources

Beneficial and Detrimental Roles of NLRs in Carcinogenesis [PDF]

Frontiers in Immunology, 2013
Inflammation plays a critical role in tumorigenesis and can contribute to oncogenic mutations, tumor promotion, and angiogenesis. Tumor-promoting inflammation is driven by many factors including the presence of the pro-inflammatory cytokines interleukin (IL)-1β and IL-18.
Janowski, Ann M., Kolb, Ryan, Zhang, Weizhou, Sutterwala, Fayyaz S.   +3 more
openaire   +3 more sources

Repellency of insecticides and the effect of thiacloprid on bumble bee colony development in red clover (Trifolium pratense L.) seed crops

Acta Agriculturae Scandinavica. Section B, Soil and Plant Science, 2019
The study intended to compare repellency of three insecticides on bumble bees and honey bees in Norwegian red clover (Trifolium pratense L.) seed crops, and to examine effects of thiacloprid on bumble bee colony development in the field.
Lars T. Havstad, John I. Øverland, Silja Valand, Trygve S. Aamlid   +3 more
doaj   +1 more source

Non-Contact Non-Destructive Testing Methods for Large-Scale Carbon Fiber-Reinforced Polymer Aircraft Parts

Engineering Proceedings
Non-contact NDT methods that can provide fast, automated, in-line quality assurance information on the manufacturing and maintenance of large-scale, thin-walled aircraft parts are necessary for the implementation of thermoplastic CFRP in the next ...
Daniella B. Deutz, Arnoud F. Bosch, Dion E. Baptista, Erik S. Veen, D. Jacco Platenkamp, H. Patrick Jansen   +5 more
doaj   +1 more source

Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles [PDF]

Cell Host & Microbe, 2017
To establish infection, pathogens deploy effectors to modify or remove host proteins. Plant immune receptors with nucleotide-binding, leucine-rich repeat domains (NLRs) detect these modifications and trigger immunity. Plant NLRs thus guard host "guardees." A corollary is that autoimmunity may result from inappropriate NLR activation because mutations ...
Lolle, Signe, Greeff, Michael Christiaan, Petersen, Klaus, Roux, Milena Edna, Jensen, Michael Krogh, Bressendorff, Simon, Rodriguez Gomes, Eleazar José, Sømark, Kenneth, Mundy, John, Petersen, Morten   +9 more
openaire   +4 more sources

The PEP++ study protocol: a cluster-randomised controlled trial on the effectiveness of an enhanced regimen of post-exposure prophylaxis for close contacts of persons affected by leprosy to prevent disease transmission

BMC Infectious Diseases
Background Leprosy is an infectious disease with a slow decline in global annual caseload in the past two decades. Active case finding and post-exposure prophylaxis (PEP) with a single dose of rifampicin (SDR) are recommended by the World Health ...
Duane C. Hinders, Anneke T. Taal, Suchitra Lisam, Aymée M. da Rocha, Nand Lal Banstola, Prativa Bhandari, Abhijit Saha, Jugal Kishore, Virginia O. Fernandes, Abu Sufian Chowdhury, Anna T. van ‘t Noordende, Liesbeth Mieras, Jan Hendrik Richardus, Wim H. van Brakel   +13 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Multi-Modal Life Cycle Assessment of Journeys by Aircraft, Train or Passenger Car

Aerospace
To reduce the carbon footprint of transport, policymakers are simultaneously stimulating cleaner vehicles and more sustainable mobility choices, such as a shift to rail for short-haul flights within Europe.
R. J. Roosien, M. N. A. Lim, S. M. Petermeier, W. F. Lammen   +3 more
doaj   +1 more source