Results 31 to 40 of about 229,010 (267)

The PEP++ study protocol: a cluster-randomised controlled trial on the effectiveness of an enhanced regimen of post-exposure prophylaxis for close contacts of persons affected by leprosy to prevent disease transmission

BMC Infectious Diseases
Background Leprosy is an infectious disease with a slow decline in global annual caseload in the past two decades. Active case finding and post-exposure prophylaxis (PEP) with a single dose of rifampicin (SDR) are recommended by the World Health ...
Duane C. Hinders, Anneke T. Taal, Suchitra Lisam, Aymée M. da Rocha, Nand Lal Banstola, Prativa Bhandari, Abhijit Saha, Jugal Kishore, Virginia O. Fernandes, Abu Sufian Chowdhury, Anna T. van ‘t Noordende, Liesbeth Mieras, Jan Hendrik Richardus, Wim H. van Brakel   +13 more
doaj   +1 more source

Non-Contact Non-Destructive Testing Methods for Large-Scale Carbon Fiber-Reinforced Polymer Aircraft Parts

Engineering Proceedings
Non-contact NDT methods that can provide fast, automated, in-line quality assurance information on the manufacturing and maintenance of large-scale, thin-walled aircraft parts are necessary for the implementation of thermoplastic CFRP in the next ...
Daniella B. Deutz, Arnoud F. Bosch, Dion E. Baptista, Erik S. Veen, D. Jacco Platenkamp, H. Patrick Jansen   +5 more
doaj   +1 more source

Experiences with Ultra-High-Bypass Simulators From Calibration and Isolated Engine Testing. [PDF]

, 1996
Investigations were carried out within a DLR/DNW/NLR co-operation on two Ultra-High Bypass Ratio engine simulators. These so-called CRUF (Counter Rotating Ultra-high bypass Fan) simulators were tested in isolation at low speed (July 1994) in the German ...
Hegen, G.H., Kiock, R., Hegen, G.H.*
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Multi-Modal Life Cycle Assessment of Journeys by Aircraft, Train or Passenger Car

Aerospace
To reduce the carbon footprint of transport, policymakers are simultaneously stimulating cleaner vehicles and more sustainable mobility choices, such as a shift to rail for short-haul flights within Europe.
R. J. Roosien, M. N. A. Lim, S. M. Petermeier, W. F. Lammen   +3 more
doaj   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang, Zilin Xu, Ran Duan, Chunxiao Lu, Da Zhou, Chen Zhou, Ran Meng, Xunming Ji   +7 more
wiley   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source