Results 81 to 90 of about 300,840 (336)

Multi-Modal Life Cycle Assessment of Journeys by Aircraft, Train or Passenger Car

open access: yesAerospace
To reduce the carbon footprint of transport, policymakers are simultaneously stimulating cleaner vehicles and more sustainable mobility choices, such as a shift to rail for short-haul flights within Europe.
R. J. Roosien   +3 more
doaj   +1 more source

Gemini Long-slit Observations of Luminous Obscured Quasars: Further Evidence for an Upper Limit on the Size of the Narrow-Line Region [PDF]

open access: yes, 2014
We examine the spatial extent of the narrow-line regions (NLRs) of a sample of 30 luminous obscured quasars at $0.4 < z < 0.7$ observed with spatially resolved Gemini-N GMOS long-slit spectroscopy.
Greene, Jenny E.   +6 more
core   +1 more source

Editorial: NLR-Protein Functions in Immunity [PDF]

open access: yesFrontiers in Immunology, 2015
Since Janeway (1) and Matzinger (2) put forward two distinct concepts of innate immune recognition, arguing that the driving force that initiates immune reponses is the recognition of microbial patterns or endogenous danger signals, respectively, we have acquired a tremendous wealth of knowledge of the protein families involved.
Fritz, Jörg H., Kufer, Thomas A.
openaire   +2 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Plant NLR immunity activation and execution: a biochemical perspective

open access: yesOpen Biology
Plants deploy cell-surface and intracellular receptors to detect pathogen attack and trigger innate immune responses. Inside host cells, families of nucleotide-binding/leucine-rich repeat (NLR) proteins serve as pathogen sensors or downstream mediators ...
Federica Locci, Jane E. Parker
semanticscholar   +1 more source

Transducers Across Scales and Frequencies: A System‐Level Framework for Multiphysics Integration and Co‐Design

open access: yesAdvanced Materials Technologies, EarlyView.
Transducers convert physical signals into electrical and optical representations, yet each mechanism is bounded by intrinsic trade‐offs across bandwidth, sensitivity, speed, and energy. This review maps transduction mechanisms across physical scale and frequency, showing how heterogeneous integration and multiphysics co‐design transform isolated ...
Aolei Xu   +8 more
wiley   +1 more source

A Secondary Control Framework for Microgrid Interoperability With Vendor-Agnostic Grid-Forming Units: Design, Implementation, and Demonstration via Large-Scale Hardware Setup

open access: yesIEEE Access
The reliable operation of islanded microgrids increasingly depends on secondary controls that restore voltage and frequency to nominal values and ensure accurate active and reactive power sharing.
Soham Chakraborty   +3 more
doaj   +1 more source

Emission-line Diagnostics of Low Metallicity AGN [PDF]

open access: yes, 2006
Current emission-line based estimates of the metallicity of active galactic nuclei (AGN) at both high and low redshifts indicate that AGN have predominantly solar to supersolar metallicities. This leads to the question: do low metallicity AGN exist?
Groves, Brent   +2 more
core   +3 more sources

Plant pathogens convergently evolved to counteract redundant nodes of an NLR immune receptor network

open access: yesbioRxiv, 2021
In plants, NLR (nucleotide-binding domain and leucine-rich repeat-containing) proteins can form receptor networks to confer hypersensitive cell death and innate immunity.
L. Derevnina   +15 more
semanticscholar   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

open access: yesAdvanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang   +16 more
wiley   +1 more source

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