Results 91 to 100 of about 122,087 (266)

Table2_Genome-wide identification and analysis of the NLR gene family in Medicago ruthenica.XLSX

, 2023
Medicago ruthenica, important forage in the legume family, possesses high nutritional value and carries abundant tolerance genes. This study used whole-genome data of M.
Yutong Zhang (4844703), Chunyan Tong (14367153), Fengling Shi (10025705)   +2 more
core   +1 more source

Predicting the Efficacy of Adjuvant Chemotherapy Using Immuno‐Nutritional and Inflammatory Markers in Elderly Patients With Stage III Colorectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
This study aimed to determine whether immuno‐nutritional and inflammatory markers could serve as predictors of the outcomes of postoperative adjuvant chemotherapy for stage III colorectal cancer in elderly patients. Postoperative lymphocyte‐to‐monocyte ratio and postoperative C‐reactive protein‐to‐albumin ratio accurately predicted the efficacy of ...
Tomoya Tago, Yasuyuki Takamizawa, Takeharu Kato, Hiroshi Nagata, Konosuke Moritani, Shunsuke Tsukamoto, Yukihide Kanemitsu   +6 more
wiley   +1 more source

DaapNLRSeek, prediction, and evolution of resistance genes in polyploid sugarcane genomes

iScience
Summary: Sugarcane (Saccharum spp. hybrids) is an important crop for sugar and biofuel production. However, pathogens cause significant yield losses.
Yiting Huang, Yingfeng Luo, Xiao Lin
doaj   +1 more source

RPW8/HR repeats control NLR activation in Arabidopsis thaliana.

PLoS Genetics, 2019
In many plant species, conflicts between divergent elements of the immune system, especially nucleotide-binding oligomerization domain-like receptors (NLR), can lead to hybrid necrosis.
Cristina A Barragan, Rui Wu, Sang-Tae Kim, Wanyan Xi, Anette Habring, Jörg Hagmann, Anna-Lena Van de Weyer, Maricris Zaidem, William Wing Ho Ho, George Wang, Ilja Bezrukov, Detlef Weigel, Eunyoung Chae   +12 more
doaj   +1 more source

Lymphocyte‐C‐Reactive Protein Ratio as Promising New Marker for Predicting Surgical Site Infection in Children With Ulcerative Colitis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Surgical site infection (SSI) is a major complication after ileal pouch–anal anastomosis (IPAA) in pediatric ulcerative colitis (UC), significantly impairing quality of life. The lymphocyte‐to–C‐reactive protein ratio (LCR), a composite marker of systemic inflammation and immune/nutritional status, has emerged as a potential ...
Yuhki Koike, Koki Higashi, Yuki Sato, Yuka Nagano, Tadanobu Shimura, Takahito Kitajima, Kohei Matsushita, Yoshiki Okita, Yoshinaga Okugawa, Yuji Toiyama   +9 more
wiley   +1 more source

NLR network mediates immunity to diverse plant pathogens

, 2017
Both plants and animals rely on nucleotide-binding domain and leucine-rich repeat-containing (NLR) proteins to respond to invading pathogens and activate immune responses. An emerging concept of NLR function is that “sensor” NLR proteins are paired with “
Terauchi, Ryohei, Vossen, Jack H., Ryohei Terauchi, Bozkurt, TO, Abd-El-Haliem, Ahmed, Abd-El-Haliem, A, Wu, C-H, Terauchi, R, Chih-Hang Wu, Belhaj, Khaoula, Kamoun, Sophien, Khaoula Belhaj, Jack H. Vossen, Belhaj, K, Vossen, JH, Wu, Chih-Hang, Bozkurt, Tolga O., Tolga O. Bozkurt, Sophien Kamoun, Ahmed Abd-El-Haliem, Kamoun, S, Wu, Chih Hang   +21 more
core   +1 more source

The dynamic TaRACK1B-TaSGT1-TaHSP90 complex modulates NLR-protein-mediated antiviral immunity in wheat

Cell Reports
Summary: Nucleotide-binding leucine-rich repeat (NLR) proteins contribute widely to plant immunity by regulating defense mechanisms through the elicitation of a hypersensitive response (HR).
Haichao Hu, Tianye Zhang, Jinnan Wang, Jun Guo, Yaoyao Jiang, Qiansheng Liao, Lu Chen, Qisen Lu, Peng Liu, Kaili Zhong, Jiaqian Liu, Jianping Chen, Jian Yang   +12 more
doaj   +1 more source

Therapeutic Silencing of Tmprss6 Reduces Iron‐Induced Inflammation and Prolongs Survival in MDS Mice

American Journal of Hematology, EarlyView.
ABSTRACT Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematopoietic disorders characterized by ineffective hematopoiesis, cytopenias, and an increased risk of progression to acute myeloid leukemia (AML). Despite advances in supportive and targeted therapies, disease‐modifying interventions remain limited.
Shahla Vilcassim, Nuttanan Pholngam, Rattanawan Thubthed, Tiwaporn Nualkaew, Saovaros Svasti, Pornthip Chaichompoo, Kai Kysenius, Peter J. Crouch, Sibylle Dames, Mona Eisermann, Alberto Martinez, Ute Schaeper, Jim Vadolas, George Grigoriadis   +13 more
wiley   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Two unequally redundant "helper" immune receptor families mediate Arabidopsis thaliana intracellular "sensor" immune receptor functions.

PLoS Biology, 2020
Plant nucleotide-binding (NB) leucine-rich repeat (LRR) receptor (NLR) proteins function as intracellular immune receptors that perceive the presence of pathogen-derived virulence proteins (effectors) to induce immune responses.
Svenja C Saile, Pierre Jacob, Baptiste Castel, Lance M Jubic, Isai Salas-Gonzáles, Marcel Bäcker, Jonathan D G Jones, Jeffery L Dangl, Farid El Kasmi   +8 more
doaj   +1 more source