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Cytofluorometric Quantification of Cell Death Elicited by NLR Proteins

2016
Nucleotide-binding domain and leucine-rich repeat containing (NLR) proteins, also known as NOD-like receptors, are critical components of the molecular machinery that senses intracellular danger signals to initiate an innate immune response against invading pathogens or endogenous sources of hazard. The best characterized effect of NLR signaling is the
Valentina, Sica   +4 more
openaire   +2 more sources

Transfer and modification of NLR proteins for virus resistance in plants

Current Opinion in Virology, 2017
NLR proteins confer resistance to multiple types of biotrophic pathogens, including viruses. NLRs are highly variable in sequence, suggesting that they are under selection pressure, but also that they may be manipulated to generate proteins with new recognition specificities.
openaire   +2 more sources

NLRs: Nucleotide-Binding Domain and Leucine-Rich-Repeat-Containing Proteins

EcoSal Plus, 2009
Eukaryotes have evolved strategies to detect microbial intrusion and instruct immune responses to limit damage from infection. Recognition of microbes and cellular damage relies on the detection of microbe-associated molecular patterns (MAMPs, also called PAMPS, or pathogen-associated molecular patterns) and so-called "danger signals" by ...
Leticia A M, Carneiro   +5 more
openaire   +2 more sources

Tsw: an NLR protein that keeps viruses away

Plant Cell Reports, 2023
Priya Gahlowt   +3 more
openaire   +2 more sources

Characterization of the human NLR protein NLRC5 [PDF]

open access: possible, 2013
Nucleotide-binding domain, leucine-rich repeat (NLR)-containing proteins play important roles in the innate immune system as intracellular pattern recognition receptors. The most prominent members, NOD1, NOD2 and NLRP3 have been extensively shown to trigger NF-kB activation or IL-1b/IL-18 processing upon pathogen infection, respectively.
openaire  

Balanced plant helper NLR activation by a modified host protein complex

Nature
Nucleotide-binding leucine-rich repeat (NLR) receptors play crucial roles in plant immunity by sensing pathogen effectors1. In Arabidopsis, certain sensor NLRs function as NADases to catalyse the production of second messengers2,3, which can be recognized by enhanced disease susceptibility 1 (EDS1) with its partner senescence-associated gene 101 ...
Shijia Huang   +12 more
openaire   +3 more sources

Update on the domain architectures of NLRs and R proteins

Biochemical and Biophysical Research Communications, 2006
Albrecht, M., Takken, F.L.W.
openaire   +4 more sources

The wheels of destruction: Plant NLR immune receptors are mobile and structurally dynamic disease resistance proteins

Current Opinion in Plant Biology, 2023
Samuel Shepherd   +2 more
exaly  

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