Results 231 to 240 of about 134,694 (275)

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, Volume 183, Issue 10, Page 2177-2196, May 2026.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source

Associations of obesity, systemic inflammation, and hyperinsulinemia with the incidence of non‐communicable chronic disease and mortality: A prospective cohort study

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3883-3894, May 2026.
Abstract Aims Obesity, systemic inflammation, and hyperinsulinemia are all features of metabolic syndrome and frequently occur together. We aimed to evaluate the association of body mass index (BMI) with incident non‐communicable chronic disease (NCD) or all‐cause mortality, independent of C‐reactive protein (CRP) and fasting insulin.
Natasha Wiebe, Stephanie Thompson, Peter Stenvinkel, Aminu Bello, Matthew T. James, Marcello Tonelli   +5 more
wiley   +1 more source

Pm37 as a susceptible Sr22 allele confers resistance to wheat powdery mildew and leaf rust. [PDF]

Nat Commun
Jin Y, Li W, Li Y, Li D, Yan H, Chen S, Han G, Xiao B, Li B, Lu P, Chen Y, Wang Y, Su F, Yu N, Zhang J, Wang K, Liu Z, He H, Liu C, Wu Q, Ma P.   +20 more
europepmc   +1 more source

The Role of NLRP1, AIM2 and MEFV Inflammasomes in the High‐Intensity Interval Training of Individuals With Obesity

Immunology, Volume 178, Issue 1, Page 109-117, May 2026.
This study shows that 8 weeks of high‐intensity interval training (HIIT) modulate inflammasome‐related gene expression in individuals with obesity. HIIT increased AIM2, MEFV, CARD16 and CARD18 expression, with CARD16 upregulation supporting reduced inflammation through inhibition of caspase‐1 activation and lower IL‐1β levels.
Ana Luíza Pereira Assunção Silveira, Daniela Alves de Abreu, Amanda de Lima Santos Musto, Luiz Henrique da Silva Nali, Jônatas Bussador do Amaral, André Luis Lacerda Bachi, Marina Tiemi Shio, Paula Rezende‐Teixeira, Carolina Nunes França   +8 more
wiley   +1 more source

Correlation between the neutrophil‐to‐lymphocyte ratio and enlarged perivascular spaces in type 2 diabetes mellitus

Journal of Diabetes Investigation, Volume 17, Issue 5, Page 844-850, May 2026.
ABSTRACT Aims To determine the relationship between the neutrophil‐to‐lymphocyte ratio and enlarged perivascular spaces in patients with type 2 diabetes mellitus. Materials and Methods Cranial magnetic resonance imaging data from 200 patients with type 2 diabetes mellitus were analyzed to categorize enlarged perivascular spaces in the basal ganglia and
Wei Zhang, Zhen Wang, Yaping Sun, Shaofeng Xu, Lei Zhu, Xiaolei Li   +5 more
wiley   +1 more source

Pan-NLR gene family analyses decipher evolutionary dynamics, population diversity, and potential disease resistance genes in cucumber. [PDF]

BMC Plant Biol
Zhang B, Deng Y.
europepmc   +1 more source

The Dual Role of Methyl Caffeate: Growth Inhibition of Pseudomonas syringae and Induction of Resistance to Bacterial Speck Disease in Tomato

Molecular Plant Pathology, Volume 27, Issue 5, May 2026.
Methyl caffeate exhibits dual functionality against Pseudomonas syringae pv. tomato. It directly disrupts bacterial membrane integrity, induces reactive oxygen species accumulation, and inhibits flagellar motility and the type III secretion system. Concurrently, it primes plant defence by activating defence‐related gene expression and enzyme activities,
Yarui Yang, Jikai Yu, Jinxi Yang, Yulin Wang, Wenrui Hou, Dongfang Zhang, Jianquan Wang, Wenfeng Nie, Yan Zhang, Xiaoyun Wang, Xiuming Li, Qinghua Shi   +11 more
wiley   +1 more source

Clinical applications of blood cell ratios in veterinary hematology: From diagnosis to prognosis. [PDF]

Vet Anim Sci
Lotfalizadeh N, Nazifi S.
europepmc   +1 more source

The Relationship Between Neutrophil/Lymphocyte Ratio and the Progression and Clinical Features of Alzheimer's Disease. [PDF]

Sisli Etfal Hastan Tip Bul
Omercikoglu Ozden H, Ustuner FS, Ucar MB, Durmaz Celik FN.   +3 more
europepmc   +1 more source