Results 211 to 220 of about 122,087 (266)

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, Volume 13, Issue 31, 4 June 2026.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Alternative splicing: an underexplored layer in immune receptor regulation, systemic resistance and priming. [PDF]

Front Plant Sci
Aballay FE, León Sánchez IJ, Benelli C, Roychoudhry S, Cambiagno DA, Petrillo E, Cecchini NM.   +6 more
europepmc   +1 more source

Zebrafish as an Anti‐Isogenic Vertebrate Model and What It Reveals About Genetic Background and Reproducibility

BioEssays, Volume 48, Issue 6, June 2026.
Zebrafish illustrates how polygenic sex determination, maternal germline bottlenecks, and a structurally restless genome jointly destabilize deep homozygosity. These interlocking constraints make fully isogenic zebrafish lines effectively unattainable, turning this model into a natural “stress test” for assumptions about genetic background and ...
Álvaro J. Arana, Laura Sánchez
wiley   +1 more source

Integrated Blood Inflammatory Ratios and Cerebrospinal Fluid Blood‒Brain Barrier Dysfunction Predict Relapse Risk in Neuromyelitis Optica Spectrum Disorder

Brain and Behavior, Volume 16, Issue 6, June 2026.
ABSTRACT Background Relapse is the primary driver of irreversible disability accumulation in neuromyelitis optica spectrum disorder (NMOSD). Although aquaporin‐4 immunoglobulin G (AQP4‐IgG) is central to disease diagnosis and pathogenesis, reliable tools for individualized relapse risk stratification remain limited.
Xingyue Zheng, Jing Shi, Hao Yin, Huiqun Song, Quanhua Zhai, Cuiping Si, Jianwen Chen, Peixue Li, Lei Zhang, Yuzhi Li, Chunbo Dong, Huakun Liu   +11 more
wiley   +1 more source

Editorial: The role of nod-like receptor (NLR) family of proteins in inflammation. [PDF]

Front Immunol
Dhar A, Jaiswal RK, Zaki H, Jeyaseelan S.   +3 more
europepmc   +1 more source

Sleep Traits and Cognitive Function: A Prospective Cohort Study With Exploration of Inflammatory Biomarkers

Brain and Behavior, Volume 16, Issue 6, June 2026.
ABSTRACT Introduction Although sleep disturbance is closely linked to cognitive impairment, the specific sleep‐related characteristics driving this deficit remain undetermined, with the mechanistic contribution of biomarkers also poorly characterized.
Chi Peng, Fan Yang, Fanfan Li, Ronghui Zhu, Lei Li, Zhentao Zhang, Jianyao You, Rui Wang, Yingyi Qin, Shuogui Xu   +9 more
wiley   +1 more source

A reference genome sequence for the exceptionally long-lived Great Basin bristlecone pine, Pinus longaeva. [PDF]

G3 (Bethesda)
Neale DB, Zimin AV, Millar CI, McGuire PE, Hosea JA, Li E, Puiu D, Timp W, Salzberg SL.   +8 more
europepmc   +1 more source

Association Between Systemic Inflammation Response Index and Specific Depressive Symptoms: Evidence From a Cross‐Sectional Survey

Brain and Behavior, Volume 16, Issue 6, June 2026.
The study investigated the association between systemic inflammation response index (SIRI) and individual depressive symptoms. Multivariable‐adjusted associations between SIRI and symptoms of anhedonia, sleep disturbance, fatigue, and appetite changes were reported.
Moshui Shan, Bei Hu, Siyi Zhao, Shuhua Wang, Yu Pan   +4 more
wiley   +1 more source

A unique echinoderm NLR triggers Vibrio phagocytosis by promoting microtubule severing to facilitate microfilament polymerization. [PDF]

J Biol Chem
Zhu J, Chen K, Li Y, Liang Y, Li C.
europepmc   +1 more source

New Insights Into the Role of Neutrophils in Lymphoma

Cancer Medicine, Volume 15, Issue 6, June 2026.
Tissue‐resident neutrophils challenge conventional paradigms by actively infiltrating normal lymphoid organs, predominantly localizing in interstitial compartments, a spatial distribution distinct from their classical vascular positioning. Neutrophils in lymphoid organs exhibit unique phenotypic and functional signatures, suggesting they play roles in ...
Ling Gu
wiley   +1 more source