Results 221 to 230 of about 134,694 (275)
The triglyceride-glucose index and neutrophil-to-lymphocyte ratio jointly predict the no-reflow phenomenon in T2DM patients with STEMI after primary PCI. [PDF]
Yang J, Xu D, Liu X, Zhao Z, Zhang J.
europepmc +1 more source
This study employed an ultrasonic‐assisted extraction (UAE) method combined with column chromatography purification to obtain two homogeneous polysaccharides (CVP‐I and CVP‐II) from Conioselinum vaginatum, which exhibited distinct physicochemical properties and structural characteristics, and exerted anti‐inflammatory effects by inhibiting the ...
Conghui Ren +6 more
wiley +1 more source
Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance. [PDF]
Kumar V +7 more
europepmc +1 more source
ABSTRACT Background and Aims Coronary artery disease (CAD) is a leading cause of mortality worldwide, with inflammation playing a crucial role in its pathogenesis. The neutrophil‐to‐lymphocyte ratio (NLR) and platelet‐to‐lymphocyte ratio (PLR) are emerging as potential inflammatory biomarkers for CAD severity. This study investigates the association of
Ladan Ayazkhoo +5 more
wiley +1 more source
Miltirone promotes pyroptosis via increasing pyroptosis-related protein NLRP3 and AIM2 in kidney renal clear cell carcinoma. [PDF]
Huang T +7 more
europepmc +1 more source
ABSTRACT Introduction Metabolic dysfunction‐associated steatotic liver disease (MASLD) has become a leading cause of chronic liver disease worldwide, yet simple and reliable non‐invasive markers for fibrosis assessment remain limited. Accessible blood‐based indicators could aid early detection of significant fibrosis.
Ghannei Olfa +4 more
wiley +1 more source
Predicting Different Recurrence Risk in HNSCC Using Circulating Inflammatory and T‐Cell Biomarkers
ABSTRACT Objective Head and neck squamous cell carcinoma (HNSCC) lacks reliable prognostic circulating biomarkers, and the role of the immune system in its progression remains incompletely understood. This study aimed to evaluate the prognostic value of systemic inflammatory and immune biomarkers in surgically treated patients with primary oral cavity (
Riccardo Gili +10 more
wiley +1 more source
Engineering PRRs: A new path to durable resistance. [PDF]
Wang D, Li Z, Yang W, Que Y, Chang M.
europepmc +1 more source
High‐Throughput Screening Reveals That CeeNU Acts as a New NLRP3 Inflammasome Inhibitor
We conducted a high‐throughput screen of 2747 FDA‐approved drugs to identify inhibitors of pyroptosis. We found that CeeNU significantly repressed NLRP3‐dependent IL‐1β release and GSDMD pore‐forming complex. We identified that the arginine 335 amino acid of the NACHT domain of NLRP3 is the critical point for human NLRP3 and CeeNU interaction and ...
Sen‐Lin Ji +11 more
wiley +1 more source
Competition for Chaperones: A Trade-Off Between Thermotolerance and Antiviral Immunity in Plants. [PDF]
Madirov A +4 more
europepmc +1 more source

