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Bacterial NLR-related proteins protect against phage
Cell, 2023Bacteria use a wide range of immune pathways to counter phage infection. A subset of these genes shares homology with components of eukaryotic immune systems, suggesting that eukaryotes horizontally acquired certain innate immune genes from bacteria.
Emily M Kibby +2 more
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Functional diversification of structurally alike NLR proteins in plants
Plant Science, 2018In due course of evolution many pathogens alter their effector molecules to modulate the host plants' metabolism and immune responses triggered upon proper recognition by the intracellular nucleotide-binding oligomerization domain containing leucine-rich repeat (NLR) proteins.
Joydeep Chakraborty +2 more
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Diverse NLR immune receptors activate defence via the RPW8‐NLR NRG1 [PDF]
New Phytologist, 2019 Most land plant genomes carry genes that encode RPW8-NLR Resistance (R) proteins. Angiosperms carry two RPW8-NLR subclasses: ADR1 and NRG1. ADR1s act as 'helper' NLRs for multiple TIR- and CC-NLR R proteins in Arabidopsis. In angiosperm families, NRG1 co-
Baptiste Castel +2 more
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COMPARISON OF MACHINE LEARNING TECHNIQUES FOR PREDICTING NLR PROTEINS
Biomedical Engineering: Applications, Basis and Communications, 2022The nucleotide-binding domain leucine-rich repeat-containing (NLR) proteins plays significant role in the intestinal tissue repair and innate immunity. It recently added to the members of innate immunity effectors molecules. It also plays an essential role in intestinal microbiota and recently emerged as a crucial hit for developing ulcerative colitis
null Nadia +2 more
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Mammalian NLR proteins; discriminating foe from friend
Immunology & Cell Biology, 2007Eukaryotic organisms of the plant and animal kingdoms have developed evolutionarily conserved systems of defence against microbial pathogens. These systems depend on the specific recognition of microbial products or structures by molecules of the host innate immune system.
Maria, Kaparakis +2 more
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The role of NLR proteins in Leishmaniasis
2018<p>Leishmania species are vector-borne protozoan parasites that cause a spectrum of human diseases, with an estimated 12 million people infected in 88 countries. Inflammation plays distinct roles in the different clinical syndromes. Visceral leishmaniasis, in which parasites migrate from the site of infection and proliferate in liver and spleen ...
Gwendolyn Mary Clay +5 more
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NACHT-LRR proteins (NLRs) in bacterial infection and immunity
Trends in Microbiology, 2005Eukaryotes have evolved systems to detect bacterial intrusion. Recognition of bacteria relies on the sensing of pathogen associated molecular patterns (PAMPs) by host pattern recognition molecules (PRMs), which include various families of leucine-rich repeat (LRR) bearing proteins in plants and animals.
Thomas A, Kufer +2 more
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Bacterial NLR-related proteins protect against phage
2022Bacteria use a wide range of immune systems to counter phage infection. A subset of these genes share homology with components of eukaryotic immune systems, suggesting that eukaryotes horizontally acquired certain innate immune genes from bacteria.
Emily M. Kibby +6 more
openaire +1 more source