Results 131 to 140 of about 98,851 (337)

Dissection of Two Complex Clusters of Resistance Genes in Lettuce (Lactuca sativa)

Molecular Plant-Microbe Interactions, 2015
Of the over 50 phenotypic resistance genes mapped in lettuce, 25 colocalize to three major resistance clusters (MRC) on chromosomes 1, 2, and 4. Similarly, the majority of candidate resistance genes encoding nucleotide binding-leucine rich repeat (NLR ...
Marilena Christopoulou, Leah K. McHale, Alex Kozik, Sebastian Reyes-Chin Wo, Tadeusz Wroblewski, Richard W. Michelmore   +5 more
doaj   +1 more source

Innate immune receptors for cross-presentation: The expanding role of NLRs

Molecular Immunology, 2019
A critical role of pattern recognition receptors (PRRs) is to influence adaptive immune responses by regulating antigen presentation. Engagement of PRRs in dendritic cells (DCs) increases MHC class I antigen presentation and CD8+ T-cell activation by cross-presented peptides but the molecular mechanisms underlying these effects are not completely ...
Corridoni, D, Simmons, A
openaire   +3 more sources

Neutrophil to Lymphocyte and Lymphocyte to Monocyte Ratios Predict Improved Survival and Response to Induction Chemotherapy in Locally Advanced Squamous Cell Carcinoma of the Larynx

Head &Neck, EarlyView.
ABSTRACT Background University of Michigan Cancer Center (UMCC) protocol 9520 treated stage III/IV locally advanced squamous cell carcinoma of the larynx (LASCCL) with cisplatin and 5‐fluorouracil to select for definitive therapy based on response.
Zachary Risch, Emily Bellile, Moneb S. Bughrara, Paul L. Swiecicki, Keith Casper, Kelly Malloy, Norman Hogikyan, Matthew Spector, Andrew Shuman, Chaz Stucken, Steven Chinn, Douglas C. Chepeha, Shruti Jolly, Michelle Mierzwa, Carol Bradford, Avraham Eisbruch, Thomas Carey, Mark Prince, Gregory T. Wolf, Francis P. Worden   +19 more
wiley   +1 more source

Novel particulate vaccine candidates recombinantly produced by pathogenic and nonpathogenic bacterial hosts : a thesis presented in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Microbiology at Massey University, Manawatu, New Zealand. [PDF]

, 2017
Polyhydroxyalkanoates (PHAs) are biopolyesters synthesized as small spherical cytoplasmic inclusion bodies by a range of bacteria. Recently, PHA beads have been investigated for use as a vaccine delivery platform by using engineered heterologous ...
Lee, Jason Wong
core  

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

The soybean plasma membrane GmDR1 protein conferring broad-spectrum disease and pest resistance regulates several receptor kinases and NLR proteins

Scientific Reports
Overexpression of Glycine max disease resistant 1 (GmDR1) exhibits broad-spectrum resistance against Fusarium virguliforme, Heterodera glycines (soybean cyst nematode), Tetranychus urticae (Koch) (spider mites), and Aphis glycines Matsumura (soybean ...
Micheline N. Ngaki, Subodh K. Srivastava, Wang Feifei, Madan K. Bhattacharyya   +3 more
doaj   +1 more source

Neutrophil‐to‐lymphocyte ratio at admission helps to predict the need for blood transfusion after vaginal delivery

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study assesses the association between complete blood count (CBC) parameters, including the neutrophil‐to‐lymphocyte ratio (NLR) and the platelet‐to‐lymphocyte ratio (PLR) and predicts the need for postpartum packed red blood cell transfusion (pRBCT).
Daniel Gabbai, Itamar Gilboa, Anat Lavie, Yariv Yogev, Emmanuel Attali   +4 more
wiley   +1 more source

The dynamic TaRACK1B-TaSGT1-TaHSP90 complex modulates NLR-protein-mediated antiviral immunity in wheat

Cell Reports
Summary: Nucleotide-binding leucine-rich repeat (NLR) proteins contribute widely to plant immunity by regulating defense mechanisms through the elicitation of a hypersensitive response (HR).
Haichao Hu, Tianye Zhang, Jinnan Wang, Jun Guo, Yaoyao Jiang, Qiansheng Liao, Lu Chen, Qisen Lu, Peng Liu, Kaili Zhong, Jiaqian Liu, Jianping Chen, Jian Yang   +12 more
doaj   +1 more source

Tomato I2 Immune Receptor Can Be Engineered to Confer Partial Resistance to the Oomycete Phytophthora infestans in Addition to the Fungus Fusarium oxysporum

Molecular Plant-Microbe Interactions, 2015
Plants and animals rely on immune receptors, known as nucleotide-binding domain and leucine-rich repeat (NLR)-containing proteins, to defend against invading pathogens and activate immune responses.
Artemis Giannakopoulou, John F. C. Steele, Maria Eugenia Segretin, Tolga O. Bozkurt, Ji Zhou, Silke Robatzek, Mark J. Banfield, Marina Pais, Sophien Kamoun   +8 more
doaj   +1 more source

The chromatin-remodeling protein BAF60/SWP73A regulates the plant immune receptor NLRs [PDF]

, 2021
Chien‐Yu Huang, Diana Sánchez-Rangel, Xiaobo Qin, Christine Bui, Ruidong Li, Zhenyu Jia, Xinping Cui, Hailing Jin   +7 more
openalex   +1 more source