Results 201 to 210 of about 86,244 (257)

A potato late blight pathogen effector interacts with ENTH-domain protein TOL9a and an activated helper NLR to suppress immunity. [PDF]

Sci Adv
Madhuprakash J, Toghani A, Pai H, Harvey M, Bentham AR, Seager BA, Yuen ELH, De la Concepción JC, Lawson DM, Stevenson CEM, Vergara-Cruces A, Derevnina L, Bozkurt TO, Banfield MJ, Kamoun S, Contreras MP.   +15 more
europepmc   +1 more source

Editorial: The role of nod-like receptor (NLR) family of proteins in inflammation

Frontiers in Immunology
Dhar, Atika, Jaiswal, Rishi Kumar, Zaki, Hasan, Jeyaseelan, Samithamby   +3 more
openaire   +2 more sources

Increased expression of inflammasome signaling genes and proteins in selective brain regions in the intermediate stage of Alzheimer's disease

Brain Pathology, Volume 36, Issue 5, September 2026.
Neuritic plaques increase in the intermediate stage of Alzheimer's neuropathological change. The intermediate stage of Alzheimer's disease was investigated by transcriptomics and immunohistochemistry. This revealed that inflammasome sensors NLRP1, NLRP3, and AIM2 oligomerize with ASC speck to form the inflammasome complex and initiate the downstream ...
Juan Pablo de Rivero Vaccari, David A. Davis, Andrew P. Sawaya, Susanna P. Garamszegi, Xiaoyan Sun, Ayled Barreda, Helen M. Bramlett, Sakir Humayun Gultekin, W. Dalton Dietrich, Robert W. Keane, Regina T. Vontell   +10 more
wiley   +1 more source

Better Multi‐Breed Genomic Predictions for Tropical Bull Fertility Using a Breed‐Adjusted Genomic Relationship Matrix

Journal of Animal Breeding and Genetics, Volume 143, Issue 5, Page 679-690, September 2026.
ABSTRACT The pressing requirement for agricultural systems to adopt climate change adaptation strategies specifically designed for tropical environments underscores the significance of implementing sustainable bull breeding practices in beef cattle operations.
Antonio Reverter, Pâmela A. Alexandre, Marina R. S. Fortes, Laercio R. Porto‐Neto   +3 more
wiley   +1 more source

NLR Inflammasomes in Viral Infections: From Molecular Mechanisms to Therapeutic Interventions. [PDF]

Viruses
Hou S, Shen X, Sun D, An Y, Zhou Y, Sun X, Wang S, Liu X, Zhu M, Zhao S, Liu Z, Wu X, Liu R.   +12 more
europepmc   +1 more source

Autophagy in MASLD: A Metabolic and Precision Medicine Perspective

Liver International, Volume 46, Issue 9, September 2026.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver condition worldwide and a major contributor to cirrhosis and hepatocellular carcinoma (HCC). While metabolic triggers such as obesity and insulin resistance are key drivers of MASLD, growing evidence has identified defects in intracellular quality
Alessandra Cazzaniga, Silvia Frigo, Alessandro Cherubini, Eniada Rrapaj, Luca Valenti   +4 more
wiley   +1 more source

Engineering PRRs: A new path to durable resistance. [PDF]

aBIOTECH
Wang D, Li Z, Yang W, Que Y, Chang M.
europepmc   +1 more source

LURP1, a SARD1‐regulated protein, coordinates with the helper NLR ADR1 to promote plant immunity

New Phytologist, Volume 251, Issue 5, Page 2852-2866, September 2026.
The working model of LURP1 function in plant immunity. Upon pathogen infection, SARD1/CBP60g promotes the transcription of LURP1 directly. LURP1 likely functions as an adaptor protein that associates with the PRRs–BAK1 complexes at the plasma membrane (PM) while also interacts with the ADR1 family helper NLRs.
Xueru Liu, Weijie Huang, Zhengxi Gong, Chenying Li, Siyu Chen, Shucai Wang, Yuelin Zhang, Xin Li   +7 more
wiley   +1 more source

Assessment of N/L ratio and subclinical atherosclerosis in FH subjects with or without LDLR mutation. [PDF]

J Endocr Soc
Di Giacomo Barbagallo F, Bosco G, Di Marco M, Scilletta S, Miano N, Martedì M, Privitera I, Papa MC, Piazza C, Valenza F, Pennisi G, De Francesco EM, Malaguarnera R, Di Pino A, Piro S, Scicali R.   +15 more
europepmc   +1 more source

NLRC5‐Deficient Macrophages Promote a Tumor‐Permissive Phenotype via AXL‐ and MERTK‐Mediated Efferocytosis

The FASEB Journal, Volume 40, Issue 15, 15 August 2026.
Defective NLRC5 signaling in macrophages drives TAM phenotype and anti‐inflammatory responses via STAT3/ERK, leading to tumor‐permissive conditions and gastric lymphoid neogenesis during Helicobacter infection. ABSTRACT The innate immune protein NLRC5 plays a key role in cancer immune surveillance.
Shambel Araya Haile, Alessandra Gatta, Nina Colon, Dana J. Philpott, Thomas A. Kufer, Le Ying, Dongmei Tong, Richard L. Ferrero   +7 more
wiley   +1 more source