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Molecular studies on plant NLR immune receptors
2020In both plants and animals, nucleotide-binding leucine-rich repeat (NLR) receptors play crucial roles in the recognition of pathogen-derived molecules and the activation of defense. Sensor NLRs (sNLRs) are polymorphic with the ability to recognize relatively diverse pathogenic effectors.
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Engineering NLR immune receptors for resilient crop disease resistance
Trends in Plant SciencePlants rely on sophisticated immune systems to defend against diverse pathogens that threaten their growth, development, and global food security. Nucleotide-binding leucine-rich repeat receptors (NLRs) are a central component in plant immunity. Innovative NLR engineering may improve plant disease resistance and offer new opportunities for sustainable ...
Yan Li +4 more
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Engineering NLR immune receptors for broad-spectrum disease resistance
Trends in Plant Science, 2013Two recent reports by Maekawa et al. and Narusaka et al. demonstrated the transfer of a nucleotide-binding domain and leucine-rich repeat (NLR) family of immune receptors into evolutionarily diverged plants without causing adverse fitness consequences.
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Signal transduction pathways used by NLR-type innate immune receptors
Molecular BioSystems, 2008Abstract Proteins from the nucleotide-binding domain, LRR containing (NLR) family are involved in sensing bacterial invasion and danger signals in mammalian cells. Activation of these molecules leads to inflammatory responses which help clearance of invading pathogens.
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Mycobacterial interaction with innate receptors: TLRs, C-type lectins, and NLRs
Current Opinion in Infectious Diseases, 2008The recent discovery of novel classes of receptors, including toll-like receptors and nucleotide-binding oligomerization domain (NOD)-like receptors is challenging the crucial role of the innate immune system in the recognition of Mycobacterium tuberculosis.
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Deciphering the landscape and evolutionary trajectory of NLR immune receptors in Dioscorea alata
Plant Molecular BiologyDioscorea alata, a key tuber crop for global food security, is threatened by anthracnose disease caused by Colletotrichum gloeosporioides. However, identification of functional resistance genes against C. gloeosporioides in D. alata is challenging due to low flowering and hybridization efficiency of this plant.
Yue Wang +7 more
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Proceedings of the National Academy of Sciences of the United States of America, 2021
Junfeng Liu, You-Liang Peng
exaly
Junfeng Liu, You-Liang Peng
exaly
Proceedings of the National Academy of Sciences of the United States of America, 2023
Xinhua Sun, Junli Wang, Pok Man Ngou
exaly
Xinhua Sun, Junli Wang, Pok Man Ngou
exaly

