Results 311 to 320 of about 98,851 (337)

Signal transduction pathways used by NLR-type innate immune receptors

Molecular BioSystems, 2008
Proteins from the nucleotide-binding domain, LRR containing (NLR) family are involved in sensing bacterial invasion and danger signals in mammalian cells. Activation of these molecules leads to inflammatory responses which help clearance of invading pathogens. Recent data now shed light on the signal transduction pathways used by NLR proteins.
openaire   +2 more sources

AtCDC48A is involved in the turnover of an NLR immune receptor

The Plant Journal, 2016
SummaryPlants rely on different immune receptors to recognize pathogens and defend against pathogen attacks. Nucleotide‐binding domain and leucine‐rich repeat (NLR) proteins play a major role as intracellular immune receptors. Their homeostasis must be maintained at optimal levels in order to effectively recognize pathogens without causing autoimmunity.
Charles, Copeland, Virginia, Woloshen, Yan, Huang, Xin, Li   +3 more
openaire   +2 more sources

Mycobacterial interaction with innate receptors: TLRs, C-type lectins, and NLRs

Current Opinion in Infectious Diseases, 2008
The recent discovery of novel classes of receptors, including toll-like receptors and nucleotide-binding oligomerization domain (NOD)-like receptors is challenging the crucial role of the innate immune system in the recognition of Mycobacterium tuberculosis.
openaire   +2 more sources

Conserved transcription factors NRZ1 and NRM1 regulate NLR receptor-mediated immunity

Plant Physiology
Abstract Plant innate immunity mediated by the nucleotide-binding leucine-rich repeat (NLR) class of immune receptors plays an important role in defense against various pathogens. Although key biochemical events involving NLR activation and signaling have been recently uncovered, we know very little about the transcriptional regulation ...
Qingling Zhang, Jubin Wang, Yuanyuan Li, Jeffrey Tung, Yingtian Deng, Barbara Baker, Savithramma P Dinesh-Kumar, Feng Li   +7 more
openaire   +2 more sources

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Chimeric antigen receptor T‐cell therapy in multiple myeloma: A comprehensive review of current data and implications for clinical practice

Ca-A Cancer Journal for Clinicians, 2023

exaly  

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-Vornhagen, Boris Böll, Victoria Metaxa   +2 more
exaly  

Breast Cancer Statistics, 2022

Ca-A Cancer Journal for Clinicians, 2022
Hyuna Sung, Kimberly D Miller, Rebecca L Siegel   +2 more
exaly  

Current treatment and recent progress in gastric cancer

Ca-A Cancer Journal for Clinicians, 2021
Smita S Joshi, Brian D Badgwell
exaly  

A review of cancer immunotherapy toxicity

Ca-A Cancer Journal for Clinicians, 2020
Lucy Boyce Kennedy
exaly