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Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance [PDF]
Advanced SciencePlant pathogens pose a significant threat to global food security by causing up to 80% agricultural yield losses. Nucleotide‐binding, leucine‐rich repeat immune receptors (NLRs) were widely proved to protect plants from a wide array of pathogens evasion.
Vinit Kumar +7 more
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Genomic organization, domain assortments, and nucleotide-binding domain diversity of NLR proteins in Sordariales fungi. [PDF]
PLoS GeneticsFungi have NOD-Like receptors (NLRs), homologous to the innate immune receptors found in animals, plants and bacteria. Fungal NLRs are characterized by a great variability of domain organizations, but the identity of the nucleotide-binding domains, the ...
Lucas Bonometti +5 more
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Comprehensive pan-cancer analysis of NLRs family as prognostic and immunity markers based on multi-omics data [PDF]
Discover OncologyBackground Members of the NOD-like receptors(NLRs)gene family members involved in inflammasome formation have been implicated in cancer initiation, development, progression, angiogenesis, and invasion.
Xianhui Wen +3 more
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NOD-like receptors in fish: evolution, structure, immune signaling, and targeting for aquaculture vaccine adjuvants [PDF]
Frontiers in ImmunologyTeleost fish possess a highly diverse innate immune system, which is well-adapted to the pathogen-rich aquatic environment in which they reside. NOD-like receptors (NLRs), a conserved family of cytosolic pattern recognition receptors, are at the center ...
Banikalyan Swain, Kavi R. Miryala
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Plant NLRs: Evolving with pathogen effectors and engineerable to improve resistance
Frontiers in Microbiology, 2022 Pathogens are important threats to many plants throughout their lifetimes. Plants have developed different strategies to overcome them. In the plant immunity system, nucleotide-binding domain and leucine-rich repeat-containing proteins (NLRs) are the ...
Biaoming Zhang +4 more
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Vietnam Journal of Science, Technology and Engineering, 2022 Slaughterhouse wastewater (SWW) possesses very high organic and nutrient concentrations and its residues are moderately solubilized, which leads to pollution affecting the environment and human health.
Minh Nhat Phan +3 more
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Teleost NOD-like receptors and their downstream signaling pathways: A brief review
Fish and Shellfish Immunology Reports, 2022 Nucleotide-binding oligomerization domain-like receptors (NOD-like receptors or NLRs) are key members of the immune system that act as intracellular sentinels.
Bhawna Chuphal, Umesh Rai, Brototi Roy
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Unmasking the invaders: NLR-mal function in plant defense
Frontiers in Plant Science, 2023 Plants possess an arsenal of immune receptors to allow for numerous tiers of defense against pathogen attack. These immune receptors can be located either in the nucleocytoplasm or on the plant cell surface.
Susanna Anbu +5 more
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Biomedical Journal, 2023 A subset of Nucleotide-binding and leucine-rich repeat-containing receptors (NLRs) function to mitigate overzealous pro-inflammatory signaling produced by NF-κB activation.
Holly A. Morrison +3 more
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The role of NOD-like receptors in innate immunity
Frontiers in Immunology, 2023 The innate immune system in vertebrates and invertebrates relies on conserved receptors and ligands, and pathways that can rapidly initiate the host response against microbial infection and other sources of stress and danger.
Cássio Luiz Coutinho Almeida-da-Silva +3 more
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