Results 11 to 20 of about 20,544 (293)
Resistify: A Novel NLR Classifier That Reveals Helitron-Associated NLR Expansion in Solanaceae
Bioinformatics and Biology InsightsNucleotide-binding domain leucine-rich repeat (NLR) proteins are a key component of the plant innate immune system. In plant genomes, NLRs exhibit considerable presence/absence variation and sequence diversity.
Moray Smith, John T Jones, Ingo Hein
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NLR proteins and parasitic disease [PDF]
Immunologic Research, 2014 Parasitic diseases are a serious global health concern. Many of the most common and most severe parasitic diseases, including Chagas' disease, leishmaniasis, and schistosomiasis, are also classified as neglected tropical diseases and are comparatively less studied than infectious diseases prevalent in high income nations.
Gwendolyn Clay +2 more
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NLR-parser: rapid annotation of plant NLR complements [PDF]
Bioinformatics, 2015 Abstract Motivation: The repetitive nature of plant disease resistance genes encoding for nucleotide-binding leucine-rich repeat (NLR) proteins hampers their prediction with standard gene annotation software. Motif alignment and search tool (MAST) has previously been reported as a tool to support annotation of NLR-encoding genes. However,
Steuernagel, Burkhard +4 more
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Animal NLRs provide structural insights into plant NLR function [PDF]
Annals of Botany, 2016 The plant immune system employs intracellular NLRs (nucleotide binding [NB], leucine-rich repeat [LRR]/nucleotide-binding oligomerization domain [NOD]-like receptors) to detect effector proteins secreted into the plant cell by potential pathogens.
Bentham, Adam +4 more
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NLR, d-NLR and PLR can be affected by many factors
International Immunopharmacology, 2021 We have read the article by Yang et al, entitled "The diagnostic and predictive role of NLR, d-NLR and PLR in COVID-19 patients" with great interest. The authors emphasized that the NLR (Neutrophil to lymphocyte ratio) is an independent prognostic biomarker for COVID-19 patients. First of all, we congratulate the authors for their valuable contribution
Bedel, Cihan +2 more
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New Phytologist, 2022 SummaryPlant intracellular nucleotide‐binding leucine‐rich repeat immune receptors (NLRs) perceive the activity of pathogen‐secreted effector molecules that, when undetected, promote colonisation of hosts. Signalling from activated NLRs converges with and potentiates downstream responses from activated pattern recognition receptors (PRRs) that sense ...
Daniel Lüdke +3 more
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Animal NLRs continue to inform plant NLR structure and function [PDF]
Archives of Biochemistry and Biophysics, 2019 Plant NLRs share many of the structural hallmarks of their animal counterparts. At a functional level, the central nucleotide-binding pocket appears to have binding and hydrolysis activities, similar to that of animal NLRs. The TIR domains of plant NLRs have been shown to self-associate, and there is emerging evidence that full-length plant NLRs may do
Burdett, Hayden +2 more
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NLR receptor networks in plants
Essays in Biochemistry, 2022 Abstract To fight off diverse pathogens and pests, the plant immune system must recognize these invaders; however, as plant immune receptors evolve to recognize a pathogen, the pathogen often evolves to escape this recognition. Plant–pathogen co-evolution has led to the vast expansion of a family of intracellular immune receptors ...
Adachi, Hiroaki, Kamoun, Sophien
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Unsolved Mysteries in NLR Biology [PDF]
Frontiers in Immunology, 2013 NOD-like receptors (NLRs) are a class of cytoplasmic pattern-recognition receptors. Although most NLRs play some role in immunity, their functions range from regulating antigen presentation (NLRC5, CIITA) to pathogen/damage sensing (NLRP1, NLRP3, NLRC1/2, NLRC4) to suppression or modulation of inflammation (NLRC3, NLRP6, NLRP12, NLRX1). However, NLRP2,
Lupfer, Christopher +1 more
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Genome-wide identification of the NLR gene family in Haynaldia villosa by SMRT-RenSeq
BMC Genomics, 2022 Background Nucleotide-binding and leucine-rich repeat (NLR) genes have attracted wide attention due to their crucial role in protecting plants from pathogens.
Zhenpu Huang +11 more
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