Results 61 to 70 of about 20,544 (293)
Frontiers in Plant Science, 2019 The nucleotide-binding domain leucine-rich repeat (NLR) immune receptors play important roles in innate plant immunity. The activation of NLRs is specifically induced by their cognate effectors released from pathogens.
Zhaowu Li +7 more
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Advanced Science, EarlyView.ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang +17 more
wiley +1 more source
AGING MEDICINE, EarlyView.The findings of this research reveal a notable and positive correlation between the Naples prognostic score and the risk of developing sarcopenia, encompassing both community residents and hospitalized patients. As a nutritional and inflammatory indicator, the Naples prognostic score can be an efficient and convenient screening tool for the clinical ...
Xinlong Ke +9 more
wiley +1 more source
NLR-Dependent Regulation of Inflammation in Multiple Sclerosis
Frontiers in Immunology, 2018 Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) associated with inappropriate activation of lymphocytes, hyperinflammatory responses, demyelination, and neuronal damage.
Marjan Gharagozloo +5 more
doaj +1 more source
Annals of Gastroenterological Surgery, EarlyView.NAT‐GS was significantly more effective only in patients with one tumor marker above the reference range, comparing those who achieved 12‐month MRFS with those who did not. ABSTRACT Aim Pancreatic cancer (PC) remains one of the most lethal malignancies, with early recurrence severely affecting prognosis even after curative resection.
Hiromichi Kawaida +9 more
wiley +1 more source
Nod-like receptors in inflammatory arthritis
Biomedical JournalNod-like receptors (NLRs) are innate immune receptors that play a key role in sensing components from pathogens and from damaged cells or organelles. NLRs form signaling complexes that can lead to activation of transcription factors or effector caspases –
Sahib Singh Madahar +2 more
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The Dual Role of Nod-like Receptors in Mucosal Innate Immunity and Chronic Intestinal Inflammation
Frontiers in Immunology, 2014 Nucleotide-binding and oligomerization domain NOD-like receptors (NLRs) are highly conserved cytosolic pattern recognition receptors (PRRs) that play, in combination with Toll-like receptors (TLRs), a critical role in innate immunity and inflammation ...
Daniele eCorridoni +6 more
doaj +1 more source
The diagnostic and predictive role of NLR, d-NLR and PLR in COVID-19 patients
International Immunopharmacology, 2020 To accumulate evidence that indicated the key role played by virus-triggered inflammation in the 2019-novel coronavirus disease (COVID-19) which emerged in Wuhan City and rapidly spread throughout China.Age, neutrophil(NEU)-to-lymphocyte (LYM) ratio (NLR), lymphocyte-to-monocyte (MON) ratio, platelet-to-lymphocyte ratio (PLR), and C-reactive protein ...
Yang, Ai-Ping +3 more
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Annals of Gastroenterological Surgery, EarlyView.This study investigates the prognostic utility of a novel volumetric indicator—psoas volume index (PVI)—for assessing sarcopenia in elderly rectal cancer patients. Sarcopenia classified by our proposed PVI cut‐off values was associated with poor nutritional and inflammatory status, and patients with low PVI showed significantly worse long‐term outcomes.
Gen Tsujio +8 more
wiley +1 more source
Scientific Reports, 2019 Gliomas are the most prevalent primary brain tumors with immense clinical heterogeneity, poor prognosis and survival. The nucleotide-binding domain, and leucine-rich repeat containing receptors (NLRs) and absent-in-melanoma 2 (AIM2) are innate immune ...
Nidhi Sharma +8 more
doaj +1 more source