This study shows that methionine synthase (MS) interacts with MATα2, responsible for SAM production, and the methyltransferase DNMT3b in the nucleus. These results support the idea that spatial compartmentalization of one‐carbon metabolism could play a major role in regulating the epigenome.
Manon Jeandel +8 more
wiley +1 more source
Economic potential and production determinants of selected neglected and conventional livestock species in Ogun and Oyo States, Nigeria: A comparative case study. [PDF]
Oguche M +6 more
europepmc +1 more source
Fusion protein condensate formation via coiled‐coil domains
Abstract While recent research shows that biomolecular condensates play important roles in normal cellular processes and diseases, the driving forces in condensate formation are not well understood, especially regarding the role of structured self‐associative protein domains.
Om Prakash Narayan +5 more
wiley +1 more source
Slow drift aware dynamic risk assessment in cyber physical systems using quantum neutrosophic fuzzy modelling. [PDF]
Kiruthika K +3 more
europepmc +1 more source
Formulation of Peptide‐Based Nanoparticles Using a Microfluidic Device
A case study using the TAMARA microfluidic device (Inside Therapeutics) was performed for peptide‐based nanoparticles under different operational parameters such as mixing channel geometry, total flow rate, and flow rate ratio. In this context, WRAP5 cell‐penetrating peptide‐based nanoparticles for siRNA or pDNA delivery demonstrated enhanced ...
Thania Hammoum +6 more
wiley +1 more source
Laser interstitial thermal therapy and adjuvant pembrolizumab in recurrent high-grade astrocytoma: a Phase 1/randomized Phase 2b trial. [PDF]
Campian JL +20 more
europepmc +1 more source
Malignant craniopharyngiomas: Institutional experience and literature review
We report the second case of malignant craniopharyngioma with BAP1 and TP53 mutations. A literature review identified 44 cases of malignant craniopharyngiomas with a median overall survival of 6 months. Eighteen (41%) occurred in patients without any history of radiation, suggesting that mechanisms other than radiation have contributed to their ...
Thomas J. Auen +10 more
wiley +1 more source
Quasi-integrability from [Formula: see text]-symmetry. [PDF]
Abhinav K, Guha P, Mukherjee I.
europepmc +1 more source
Decadal Rapid Change in Energetic Carrying Capacity for Juvenile Chum Salmon in the Sanriku Coast
ABSTRACT Adult returns to coastal rivers in Sanriku, located near the southernmost area of chum salmon distribution, have declined since 2010. Climate‐induced fluctuations in juvenile prey availability may affect growth and survival, which are linked to adult returns.
Yuki Iino +3 more
wiley +1 more source

