Results 91 to 100 of about 3,123 (185)

ISEV2020 Abstract Book

, 2020
Journal of Extracellular Vesicles, Volume 9, Issue S1, July 2020.
wiley   +1 more source

The mechanism and influence on the biological behavior of human high-metastatic large cell lung cancer cell lines with transfection of nm23-H1 gene

Chinese Journal of Lung Cancer, 2008
Background and objective It has been confirmed that nm23-H1 gene is one of the tumor metastasis suppressor genes. Up to now, the exact mechanism of nm23-H1 gene is uncertian. The aim of this study is to compare the biological behavior changes among three
Qiang NIE, Wen ZHU, Lunxu LIU, Junke FU, Dingbiao LI, Yin LI, Jun CHEN, Hongyu LIU, Qinghua ZHOU   +8 more
doaj  

Contributions of Epstein–Barr Nuclear Antigen 1 (EBNA1) to Cell Immortalization and Survival

Viruses, 2012
Epstein–Barr virus (EBV) immortalizes host cells as part of its latent mode of infection. As a result of this ability to promote cell proliferation and survival, EBV infection contributes to the development of several kinds of B-cell lymphomas and ...
Lori Frappier
doaj   +1 more source

THE METASTASIS SUPPRESSOR NM23-H1 IS REQUIRED FOR DNA REPAIR [PDF]

, 2008
NM23-H1 represents the first identified metastasis suppressor, exhibiting reduced expression in breast carcinoma and melanoma, and an ability to inhibit metastatic growth without significant impact on the transformed phenotype.
Yang, Mengmeng
core   +1 more source

Abstract Book: 25th Congress of the European Hematology Association Virtual Edition, 2020

, 2020
HemaSphere, Volume 4, Issue S1, Page 1-1168, June 2020.
wiley   +1 more source

Functional characterization of the human PRUNE protein: implications in cancer. [PDF]

, 2004
The functional characterization of H-PRUNE was performed using different approaches, in order to elucidate first the biochemical function of the protein, and then the correlation with other genes and the role in different tumour types.
D'Angelo, Anna
core   +1 more source

Construction, Expression and Purification of Wild and Mutant Type of nm23-H1 in Prokaryotic Expression System

Chinese Journal of Lung Cancer, 2009
Background and objective Nm23-H1 is a metastasis-suppressor gene. However, its molecular mechanism of suppressing metastasis is unknown until now. The aim of this study is to construct prokaryotic expression vector of wild and mutant type of nm23-H1 (WT,
Xueqin YANG, Yu FAN, Jun CHEN, Hongyu LIU, Li MA, Daxing ZHU, Dong WANG, Ge WANG, Qinghua ZHOU   +8 more
doaj  

Identification and validation of genes with expression patterns inverse to multiple metastasis suppressor genes in breast cancer cell lines [PDF]

, 2014
Metastasis suppressor genes (MSGs) have contributed to an understanding of regulatory pathways unique to the lethal metastatic process. When re-expressed in experimental models, MSGs block cancer spread to, and colonization of distant sites without ...
Caplen, Natasha J., Collins, Joshua W., Goswami, Chirayu P., Gökmen-Polar, Yesim, Hoshino, Takashi, Marino, Natascia, Merchant, Anand S., Qian, Yongzhen, Shen, Changyu, Sledge, George W., Steeg, Patricia S.   +10 more
core   +1 more source

Nasopharyngeal carcinoma: molecular biomarker discovery and progress [PDF]

, 2007
Nasopharyngeal carcinoma (NPC) is a rare malignancy in most part of the world and it is one of the most confusing, commonly misdiagnosed and poorly understood diseases.
Cho William
core   +2 more sources

Low doses of gamma ionizing radiation increase hprt mutant frequencies of TK6 cells without triggering the mutator phenotype pathway

Genetics and Molecular Biology, 2006
The TK6 lymphoblastoid cell line is known to be mismatch repair (MMR) and p53 proficient. Deficiency in MMR results in a mutator phenotype characterized by microsatellite instability (MSI) and increased hprt mutant frequency (MF).
Flávio Monteiro Ayres, Aparecido Divino da Cruz, Patricia Steele, Barry W. Glickman   +3 more
doaj   +1 more source