Prognostic and clinicopathological significance of nm23-H1 expression in non-small cell lung cancer: A meta-analysis. [PDF]
Li D +6 more
europepmc +1 more source
PuF, An Antimetastatic and Developmental Signaling Protein, Interacts with the Alzheimer’s Amyloid-β Precursor Protein via a Tissue-Specific Proximal Regulatory Element (PRE) [PDF]
Background: Alzheimer’s disease (AD) is intimately tied to amyloid-β (Aβ) peptide. Extraneuronal brain plaques consisting primarily of Aβ aggregates are a hallmark of AD. Intraneuronal Aβ subunits are strongly implicated in disease progression.
Ge, Yuan-Wen +3 more
core +3 more sources
Activation of Nm23-H1 to suppress breast cancer metastasis via redox regulation. [PDF]
Kim B, Lee KJ.
europepmc +1 more source
NDP Kinase Moves into Developing Primary Cilia [PDF]
Inmunofluorescence staining of murine NIH3T3 fibroblasts grown at high density shows that conventional nucleoside diphosphate (NDP) kinases A and B localize to a sensory organelle, the primary cilium.
Gallagher, Betty C. +3 more
core +2 more sources
The SET complex acts as a barrier to autointegration of HIV-1.
Retroviruses and retrotransposons are vulnerable to a suicidal pathway known as autointegration, which occurs when the 3'-ends of the reverse transcript are activated by integrase and then attack sites within the viral DNA.
Nan Yan +4 more
doaj +1 more source
Nm23-H1 induces apoptosis in primary effusion lymphoma cells via inhibition of NF-κB signaling through interaction with oncogenic latent protein vFLIP K13 of Kaposi's sarcoma-associated herpes virus. [PDF]
Mohanty S +7 more
europepmc +1 more source
Aldehyde dehydrogenase 1A1 and gelsolin identified as novel invasion-modulating factors in conditioned medium of pancreatic cancer cells [PDF]
Conditioned medium (CM) from clonal sub-populations of the pancreatic cancer cell line, MiaPaCa-2 with differing invasive abilities, were examined for their effect on in vitro invasion.
Alban +51 more
core +3 more sources
Molecular prognostic factors in early-stage cervical adenocarcinoma
Within the past years the proportion of cervical adenocarcinomas has increased, however, there is a shortage of data regarding immunohistochemical and molecular features and their prognostic relevance in early-stage cervical adenocarcinoma (esCAC).
Maciej Bodzek +8 more
doaj +1 more source
Effect of Inhibition of the Lysophosphatidic Acid Receptor 1 on Metastasis and Metastatic Dormancy in Breast Cancer [PDF]
Background Previous studies identified the human nonmetastatic gene 23 (NME1, hereafter Nm23-H1) as the first metastasis suppressor gene. An inverse relationship between Nm23-H1 and expression of lysophosphatidic acid receptor 1 gene (LPAR1, also known ...
Albaugh, Mary +11 more
core
ARF6-dependent regulation of P2Y receptor traffic and function in human platelets.
Adenosine diphosphate (ADP) is a critical regulator of platelet activation, mediating its actions through two G protein-coupled receptors, the P2Y(1) and P2Y(12) purinoceptors. Recently, we demonstrated that P2Y(1) and P2Y(12) purinoceptor activities are
Venkateswarlu Kanamarlapudi +4 more
doaj +1 more source

