Results 111 to 120 of about 3,123 (185)

Expression and significance of PTEN and nm23-H1 in the metastasis of non-small cell lung cancer

open access: yesChinese Journal of Lung Cancer, 2008
Background and objective It has been proven that PTEN and nm23-H1 genes were the tumor metastasis suppressor genes. Up to now, most of studies are aim at basic research.
Zhijian JIANG, Xiaoping WANG
doaj  

Strand-specific miR-28-3p and miR-28-5p have differential effects on nasopharyngeal cancer cells proliferation, apoptosis, migration and invasion

open access: yesCancer Cell International, 2019
Background MicroRNAs (miRNAs) play crucial roles in varieties of cancers, particularly in tumorigenesis, progression, and migration. Dysregulation of miR-28 was reported to occur in various types of human malignancies.
Yan Lv   +3 more
doaj   +1 more source

Molecular alterations that drive breast cancer metastasis to bone. [PDF]

open access: yes, 2015
Epithelial cancers including breast and prostate commonly progress to form incurable bone metastases. For this to occur, cancer cells must adapt their phenotype and behaviour to enable detachment from the primary tumour, invasion into the vasculature ...
Friedrich RE   +12 more
core   +1 more source

Anti-Proliferation Activity of a Decapeptide from Perinereies aibuhitensis toward Human Lung Cancer H1299 Cells

open access: yesMarine Drugs, 2019
Perinereis aibuhitensis peptide (PAP) is a decapeptide (Ile-Glu-Pro-Gly-Thr-Val-Gly-Met-Met-Phe, IEPGTVGMMF) with anticancer activity that was purified from an enzymatic hydrolysate of Perinereis aibuhitensis.
Shuoqi Jiang   +9 more
doaj   +1 more source

Site-directed Mutation of Nm23-H1 [PDF]

open access: yesJournal of Biological Chemistry, 1997
José M.P. Freije   +4 more
openaire   +1 more source

Site-directed Mutagenesis of nm23-H1 [PDF]

open access: yesJournal of Biological Chemistry, 1996
Nicholas J. MacDonald   +4 more
openaire   +1 more source

The variation of intracellular distribution and translocation of the protein kinase Cα among human lung cancer cell line with different metastasis potential

open access: yesChinese Journal of Lung Cancer, 2008
Background and objective Protein Kinase C (PKC) is one of the key kinases in the cell signal transduction passway. There are more reports about it's ability on cell proliferation, but fewer on invasion and metastasis in the past; and it's mechanisms are ...
Qinghua ZHOU   +8 more
doaj  

nm23-H1 与大肠癌淋巴结转移的相关性研究

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 1998
目的: 探讨 nm23-H1与大肠癌淋巴结转移的关系。方法: 利用限制性片段长度多态性、Southern blot 和免疫组织化 学染色技术( LSAB 法) ,检测 80 例大肠癌及正常粘膜 DNA 中 nm23-H1 杂合性缺失(nm23-H1 LOH)和石蜡组织切片中 nm23H1蛋白表达。结果: 80 例中 45 例为杂合子,其中 LOH 14例,9 例有淋巴结转移,31 例无 LOH 者,仅 6 例有淋巴结转移(P
doaj  

Bcl-2、nm23-H1和VEGF在非小细胞肺癌组织中的表达及意义

open access: yesZhongguo shiyan zhenduanxue, 2007
目的探讨Bcl-2、VEGF和nm23-H1基因在肺癌在非小细胞肺癌组织中的表达及其与淋巴结转移的关系。方法采用免疫组化S-P法检测123例非小细胞肺癌组织中Bcl-2、VEGF和nm23-H1基因的表达。结果Bcl-2蛋白的阳性表达在高、中和低分化肺癌组间比较,差异有显著性 ...
杜亚明   +3 more
doaj  

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