Clinical significance of altered
BMC Cancer, 2009 Background Clinical characterization of bladder carcinomas is still inadequate using the standard clinico-pathological prognostic markers. We assessed the correlation between nm23-H1, Rb, EGFR and p53 in relation to the clinical outcome of patients with ...
Zekri Abdel-Rahman N +5 more
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Tissue expression of CD10 protein in colorectal carcinoma: correlation with the anatomopathological features of the tumor and with lymph node and liver metastases [PDF]
, 2012 BACKGROUND: The reduced expression of CD10 may be related to unfavorable prognosis of patients with colorectal carcinoma. The authors analyzed the tissue immunostaining of CD10 protein in colorectal carcinoma and its relationship to clinicopathologic ...
Artigiani Neto, Ricardo +6 more
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Overexpression of nm23-H1 and nm23-H2 genes in colorectal carcinomas and loss of nm23-H1 expression in advanced tumour stages. [PDF]
Gut, 1995 Although a reduced expression of nm23 has been shown to correlate with a high metastatic potential in some human cancers, in colorectal cancers, conflicting data have been reported. As there are two homologous genes, nm23-H1 and nm23-H2, which encode the A and B subunits of nucleoside diphosphate kinase, efficient and simplified techniques were ...
J A, Martinez +9 more
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Receptor Activation Regulates Cortical, but not Vesicular Localization of NDP Kinase [PDF]
, 2003 We used immunofluorescence techniques to determine the localization of nucleoside diphosphate (NDP) kinase in NIH-3T3 fibroblasts. We found that cytoplasmic NDP kinase can be separated into two populations according to subcellular localization and ...
Gallagher, Betty C. +3 more
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Down-regulation of thenm23.h1 gene inhibits cell proliferation [PDF]
International Journal of Cancer, 1997 nm23 gene expression is strictly related to the state of cell growth. The level of its expression parallels the fraction of thymidine-incorporating cells (S-phase cells) in neoplastic mammary tissues and in the synchronously cycling fraction of MCF 1OA cells.
CIPOLLINI G +7 more
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Molecules, 2016 Liver cancer is the most endemic cancer in a large region of the world. This study investigated the anti-metastatic effects of an extract of Monascus purpureus CWT715 (MP) fermented from sorghum liquor biowaste and its mechanisms of action in highly ...
Wen-Teish Chang +3 more
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A humán metasztázis inhibitor nm23 géncsalád C. elegans ortológjainak genetikai analízise = A genetic characterisation of the human metastasis inhibitor nm23 orthologues in C. elegans [PDF]
, 2011 Az nm23 géncsalád első csoportjába tartozó gének nukleozid-difoszfát kinázokat (NDPK) kódolnak. Az első csoportba tartozó NDPK-ok C. elegans ortológját, az ndk-1 gént tanulmányoztuk, különös tekintettel a Ras/MAPK jelátvitelben betöltött szerepére.
Vellainé Takács, Krisztina
core
SETBP1 overexpression is a novel leukemogenic mechanism that predicts adverse outcome in elderly patients with acute myeloid leukemia [PDF]
, 2009 3 Tables. 7 Figures. The online version of this article contains a data supplement.Acute myeloid leukemias (AMLs) result from multiple genetic alterations in hematopoietic stem cells. We describe a novel t(12;18)(p13;q12) involving ETV6 in a patient with
Cristóbal, Ion +10 more
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Clinical and immunohistochemical study of eight cases with thymic carcinoma
BMC Surgery, 2002 Background Thymic carcinoma is a rare neoplasm with extremely poor prognosis. To evaluate the biological characteristics of thymic carcinoma, we reviewed 8 patients.
Shimizu Tetsuya +6 more
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Chinese Journal of Lung Cancer, 2008 Background and objective It has been proven that nm23-H1 gene is an important metastatic-suppressed gene of lung cancer. In order to screen the differential expression genes related to nm23-H1, we constructed the suppression subtractive cDNA libraries of
Sujuan YE +8 more
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