Results 281 to 290 of about 246,656 (358)

Differences in Src phosphorylation of PSD‐93 and PSD‐95 drive differences in scaffolding activity

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract Scaffold proteins contain multiple binding modules that allow for co‐localization of proteins that lack a direct interaction. Evolution resulted in different combinations of binding modules that rewired existing signal transduction pathways.
Frank A. Mindlin   +3 more
wiley   +1 more source

Efficient and rapid isolation of native AMPA receptor complexes for cryo‐EM

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract Isolating native ion channels for structural characterization is routinely achieved by extraction from membrane fractions of tissue with prolonged mild detergent treatment. AMPA receptors (AMPARs), glutamatergic receptors that mediate fast excitatory transmission and synaptic plasticity, are coassembled with diverse auxiliary subunits and ...
Jumi Park, Eric Gouaux
wiley   +1 more source

Repeated Levonorgestrel Administration Impairs Cognitive Function via Glutamatergic Transmission and CaMKII-PKA-BDNF Signaling in the Hippocampus of Female Wistar Rats. [PDF]

open access: yesJ Exp Pharmacol
Abdulrahim HA   +9 more
europepmc   +1 more source

Oral Supplementation With a Bovine Thymus Extract Reduces Neuronal Excitability in Aging Mice

open access: yesFASEB BioAdvances, Volume 8, Issue 2, February 2026.
Oral supplementation of aging mice with a nuclear fraction extract of bovine thymus (TNF) leads to significant increases in GAD65, GAD67, and β2/β3 subunits of the GABAA receptor, more so with high dose (HD) TNF treatment compared to low dose (LD) and control condition.
Abdeslem El‐Idrissi   +2 more
wiley   +1 more source

Synaptic pruning following NMDAR-dependent LTD preferentially affects isolated synapses. [PDF]

open access: yesiScience
Camus C   +8 more
europepmc   +1 more source

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