Results 281 to 290 of about 240,251 (364)

Trans-synaptic molecular context of NMDA receptor nanodomains. [PDF]

Nat Commun
Anderson MC, Dharmasri PA, Damenti M, Metzbower SR, Laghaei R, Blanpied TA, Levy AD.   +6 more
europepmc   +1 more source

Cyanide Beyond Toxicity: A Systematic Review of Its Effects on Vascular Function

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 5, November 2025.
ABSTRACT Cyanide is widely recognized for its potent toxicity, yet evidence shows that concentrations below 1 μM may enhance cytochrome c oxidase activity and have a regulatory function. Recent findings also demonstrate that mammalian cells, including endothelial cells, produce cyanide endogenously, where it can modulate mitochondrial bioenergetics ...
Elif Alan‐Albayrak, Ulf Simonsen
wiley   +1 more source

Sleep as a window into thalamocortical pathology: generative modeling implicates NMDA receptor hypofunction in 22q11.2 deletion syndrome

Berndt LCS, Diebel RM, Donnelly NA, Hall J, van den Bree MBM, Adams RA, Shaw AD, Jones MW.   +7 more
europepmc   +1 more source

Nitrergic Signaling Mediation of Neurobehavioral Responses to Stress in Zebrafish. [PDF]

J Neurochem
Heymbeeck JAA, de Sousa EB, Lima-Maximino M, Pereira A, Maximino C.   +4 more
europepmc   +1 more source

Cannabinoid CB2 receptor‐mediated analgesia: mechanism‐based insights and therapeutic potential

British Journal of Pharmacology, Volume 182, Issue 21, Page 5090-5118, November 2025.
Agonists of the cannabinoid 2 (CB2) receptor have shown promise for the treatment of pain in a variety of animal models. However, despite current preclinical evidence supporting the use of CB2 agonists for pain, successful translation of findings from preclinical models to human patients is lacking.
Kelsey G. Guenther, Andrea G. Hohmann
wiley   +1 more source

Management of Patients With Opioid Use Disorder (OUD). [PDF]

Cureus
Martin-Orr N, Yun S.
europepmc   +1 more source

Cadmium opens GluK2 kainate receptors with cysteine substitutions at the M3 helix bundle crossing [PDF]

, 2019
Huettner, James E, Wilding, Timothy J
core   +1 more source

Genetic testing in cerebral palsy with clinical and neuroimaging variables

Developmental Medicine &Child Neurology, Volume 67, Issue 11, Page 1443-1452, November 2025.
This original article is commented by Krägeloh‐Mann on pages 1376–1377 of this issue. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16334 Abstract Aim To optimize genetic testing in children with cerebral palsy (CP) by using clinical and magnetic resonance imaging (MRI) variables.
Esther M. Tantsis, Shekeeb S. Mohammad, Simon P. Paget, Yisselle I. Virella‐Perez, Velda X. Han, Dianah Hadi, Chaya Goldman, Michelle A. Farrar, Michael Fahey, Russell C. Dale, the GENE‐CP study group, Kristine Alba‐Concepcion, David J Amor, Tajul Arifin Tajudin, Nadia Badawi, Elizabeth Barnes, Bruce Bennetts, Hilla Ben Pazi, Darius Ebrahimi‐Fakhari, Darcy Fehlings, Donna M Ferriero, Jennifer Friedman, Jozef Gecz, Gladys Ho, Sachin Gupta, Rod W Hunt, Kavitha Kothur, Michael Kruer, Manju A Kurian, Maria Kyriagis, Wang Tso Lee, Sarah McIntyre, Aurélie Méneret, Jonathan W Mink, Catherine Morgan, Angela Morrow, Nardo Nardocci, Emanuela Pagliano, Elizabeth E. Palmer, Toni S Pearson, Belén Pérez‐Dueñas, Emmanuel Roze, Michael Shevell, Anna te Velde, Mary‐Clare Waugh, Michèl A Willemsen, Yana A Wilson   +46 more
wiley   +1 more source

Targeting metabotropic glutamate receptors for symptomatic and disease-modifying treatment in Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Alborghetti M, Ceccherelli A, Caridi M, Nicoletti F, Battaglia G, Bruno V.   +5 more
europepmc   +1 more source

Neuroendocrinology meets addiction: Emerging pharmacotherapies on the horizon

Journal of Internal Medicine, Volume 298, Issue 5, Page 392-423, November 2025.
Abstract Alcohol and other substance use disorders (ASUDs) are prevalent and major contributors to global morbidity and mortality. Their impact extends beyond the individual, imposing significant burdens on families, communities, healthcare systems, and society at large.
Anna Loften, Mehdi Farokhnia, Leandro F. Vendruscolo, Lorenzo Leggio   +3 more
wiley   +1 more source