Results 221 to 230 of about 1,350,887 (263)

Novel binding mode for negative allosteric NMDA receptor modulators. [PDF]

J Gen Physiol
Lotti JS, Syrenne JT, Benton AJ, Al-Mousawi A, Cornelison LE, Trolinder CJ, Yi F, Zhang Z, Yates-Hansen CK, McClelland LJ, Bosco J, Rau AR, Clausen RP, Hansen KB.   +13 more
europepmc   +1 more source

Progressive Cognitive Decline and Pyramidal Signs in a Patient With a Novel Homozygous c.395A>T; p.Lys132Met Mutation in CHCHD2

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Biallelic CHCHD2 variants are rare. We report a consanguineous man with a novel homozygous CHCHD2 c.395A>T (p.Lys132Met) variant who developed progressive cognitive decline, apraxia, oculomotor impairment, and pyramidal signs without parkinsonism.
Mehri Salari, Arash Soltani, Masoud Etemadifar, Kamran Rezaei   +3 more
wiley   +1 more source

Structure-based molecular modeling of a novel S-Remiketamine scaffold and derived arylcyclohexanone analogues: NMDA receptor dynamics, MM-GBSA ranking, and CES1-Oriented structural compatibility. [PDF]

Front Chem
Alkhatip AAAMM, Raza U, Farag E, Hamza MK, Hosny H, Sallam A, Farag AMG, Wagih M, Naguib A, Abdulmegid AM, Algameel H, Bahr MH.   +11 more
europepmc   +1 more source

A peak at the leak: Background conductances as efficient controllers of autonomous pacemaking

The Journal of Physiology, EarlyView.
Joshua A. Goldberg
wiley   +1 more source

Acute Effects of Brief Exercise on Alcohol Craving Among Young Adults With Problematic Alcohol Use: A Systematic Review

European Journal of Sport Science, Volume 26, Issue 10, October 2026.
ABSTRACT Alcohol craving is a key process in alcohol abuse, especially during young adulthood, a period of heightened vulnerability and continued brain development. Although acute physical exercise has been proposed as a potential strategy to reduce craving and modulate affective and cognitive processes, current evidence remains limited regarding its ...
P. Sampedro‐Piquero, A. Cordellat‐Marzal, M. Dragotti, L. Mandolesi, O. Gigliotta, R. D. Moreno‐Fernández   +5 more
wiley   +1 more source

NMDA Receptor: An Old but Refreshed Target for Neurodegeneration. [PDF]

NeuroSci
Marques JM, Rodrigues RJ.
europepmc   +1 more source

Spatial Collinearity Constrains Multivariate Molecular‐Enriched Network Estimation

Human Brain Mapping, Volume 47, Issue 14, October 1, 2026.
Spatial collinearity among PET maps undermines multivariate network estimation and obscures drug mechanisms. Moving from multivariate to univariate modelling resolves this instability, significantly boosting test–retest reliability and uncovering clear, receptor‐specific pharmacodynamics in pharmacoimaging data.
Timothy Lawn, Johan Nakuci, Steve C. R. Williams, Federico Turkheimer, Mitul A. Mehta   +4 more
wiley   +1 more source

Uncovering NMDA receptor-mediated high firing activity in excitatory human neurons. [PDF]

iScience
Gameiro-Ros I, Tengolics AJ, Prytkova I, Kamarajan C, Pang ZP, Goate AM, Hart RP, Slesinger PA.   +7 more
europepmc   +1 more source