Results 231 to 240 of about 1,350,887 (263)

Posttranslational Modifications of p62/SQSTM1 in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
Schematic illustration of p62 as a posttranslational modifications (PTMs)‐programmed integrator in homeostasis, pathogenesis, and therapeutic targeting. (Left) Homeostasis: In physiological states, p62, through various PTMs such as phosphorylation, ubiquitination, and acetylation, coordinates essential cellular functions.
Weikai Wang, Xin Jiang, Runing Qiu, Chandra Sugiarto Wijaya, Miaoqin Chen, Jin Wang, Liyuan Zhu, Hongchuan Jin, Lifeng Feng   +8 more
wiley   +1 more source

Environmental enrichment modulates parvalbumin interneuron deficits and plasticity-related signaling after early postnatal NMDA receptor hypofunction in male rat visual cortex. [PDF]

Brain Struct Funct
Murueta-Goyena A, Ortuzar N, Bulnes S, Lafuente JV, Bengoetxea H.   +4 more
europepmc   +1 more source

Iron and Other Metal Ions in Human Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley   +1 more source

Chronic Co-administration of Methylphenidate and Fluoxetine Reduces Striatal NMDA Receptor Binding in Adolescent Rats. [PDF]

Neurochem Res
Lagamjis G, Slayton D, Lu H, Hoerner C, Lantry AM, Marion M, Elman D, Hadjiargyrou M, Komatsu D, Thanos PK.   +9 more
europepmc   +1 more source

Task‐Related Neurotransmitter Dynamics in the Visual Cortex: A Proof‐of‐Concept Time‐Resolved fMRS Study Using a Sustained Vigilance Paradigm

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Using time‐resolved fMRS at 3T, we observed task‐evoked increases in Glx within the human primary visual cortex during sustained vigilance paradigm. Glx dynamics showed an exploratory association with behavioral performance. These findings suggest that time‐resolved fMRS may capture excitatory neurochemical changes related to sustained visual ...
I‐Ting Lee, Shang‐Hua N. Lin, Rong‐Rung Kuo, Ching‐Po Lin, Li‐Hung Chang   +4 more
wiley   +1 more source

Glycine-modulating Slc6a20a-ASO restores NMDA receptor function in SHANK2 and SHANK3-mutant mice and cortical organoids. [PDF]

Nat Commun
Roh JD, Bae M, Oh Y, Yang Y, Lee S, Hwang WC, Yang E, Kim H, Jang H, Choi HW, Kim H, Kim JY, Kim E.   +12 more
europepmc   +1 more source

Clinical Images: Tumor necrosis factor inhibitor–associated demyelination in a case of neuro‐Behçet disease

ACR Open Rheumatology, Volume 8, Issue 10, October 2026.
Eloise Norman, Gabor Major
wiley   +1 more source

Protein-protein interaction-interfering peptide rescues dysregulated NMDA receptor signaling. [PDF]

JCI Insight
Featherstone RE, Li H, Sengar AS, Borgmann-Winter KE, Melnychenko O, Crown LM, Gifford RL, Amirfathi F, Banerjee A, Tran A, Parekh K, Heller M, Zhang W, Gallop RJ, Marc AD, Komal P, Salter MW, Siegel SJ, Hahn CG.   +18 more
europepmc   +1 more source

Prenatal exposure to particulate matter impairs offspring behavior via hippocampal NMDA receptor reduction: an in vivo and ex vivo study. [PDF]

Environ Int
Eom Y, Lee HK, Kim YK, Yang S, Yim YH, Shin S, Kim JW, Yoo HM, Lee SH.   +8 more
europepmc   +1 more source

Anti-N-Methyl-D-Aspartate (NMDA) Receptor Encephalitis Presenting as Acute Psychosis and Seizures in a Patient With Multiple Sclerosis: A Diagnostic Challenge. [PDF]

Cureus
Izadian Bidgoli A, Buryk Y, Pina A.
europepmc   +1 more source