Results 261 to 270 of about 2,517,861 (360)

Immune involvement in neuropsychiatric disorders: Insights from single‐cell transcriptomic studies

Psychiatry and Clinical Neurosciences, EarlyView.
Neuropsychiatric disorders pose profound challenges to both research and treatment, largely due to their clinical heterogeneity and the limited understanding of their underlying biological mechanisms. While bulk RNA sequencing (bulk RNA‐seq) has been widely used to study gene expression, it cannot resolve cell‐type‐specific signals or detect rare ...
Tsutomu Takeda, Michihiro Toritsuka, Hiroto Tamakoshi, Nakao Iwata, Manabu Makinodan   +4 more
wiley   +1 more source

Experimentally Constrained Mechanistic and Data-Driven Models for Simulating NMDA Receptor Dynamics. [PDF]

Biomedicines
Pham DJ, Bouteiller JC.
europepmc   +1 more source

Perceptual Priors Update Contextual Feedback Processing in V1

Topics in Cognitive Science, EarlyView.
Abstract Contextual information and prior knowledge facilitate perceptual processing, improving our recognition of even distorted or obstructed visual inputs. As a result, neuronal processing elicited by identical sensory inputs varies depending on the context in which we encounter those inputs.
Yulia Y. Lazarova, Yingying Huang, Lars F. Muckli, Lucy S. Petro   +3 more
wiley   +1 more source

NMDA Receptor-Mediated Ca²⁺ Flux Attenuated by the NMDA Receptor/TRPM4 Interface Inhibitor Brophenexin. [PDF]

Pharmacol Res Perspect
Casby J, Gansemer BM, Thayer SA.
europepmc   +1 more source

Cervical epidural catheter for administration of detomidine and morphine in a model of carpal synovitis in the horse

Veterinary Surgery, EarlyView.
Abstract Objective To determine the analgesic effects of detomidine and morphine administered by cervical epidural catheter (CEC) on a model of thoracic limb pain. Study design Prospective, randomized, blinded crossover study. Animals Five adult horses.
Veronica L. Edwards, Rachel Reed, Michael Perlini, Valerie J. Moorman   +3 more
wiley   +1 more source

A causal role of the NMDA receptor in recurrent processing during perceptual integration. [PDF]

Elife
Noorman S, Stein T, Zantvoord J, Fahrenfort J, van Gaal S.   +4 more
europepmc   +1 more source

Spontaneous Ca2+ signals in the developing mammalian cochlea of live mice under different anaesthetic regimes

Experimental Physiology, EarlyView.
Abstract The pre‐hearing mouse cochlea undergoes critical periods of spontaneous Ca2+‐dependent activity that spreads across non‐sensory supporting cells and inner hair cells (IHCs). These signals have been shown to regulate not only the refinement of neural circuits along the auditory pathway towards functional maturity, but also the maturation of the
Francesca De Faveri, Walter Marcotti, Federico Ceriani   +2 more
wiley   +1 more source

Paraneoplastic Anti-NMDA Receptor Encephalitis in a Nigerian Female Teenager: A Case Report. [PDF]

Niger Med J
Nwazor E, Chukwuocha I, Iheanacho J, Ajuonuma B, Madueke O, Mgbeoma K, Ibeneme E.   +6 more
europepmc   +1 more source

Memantine, an NMDA Receptor Antagonist, Attenuates Doxorubicin-Induced Cardiac Oxidative Stress and Inflammation in Mouse 4T1 Breast Cancer Model. [PDF]

Breast Cancer (Auckl)
Ghafouri-Asbagh A, Tabatabaei K, Vaez H, Jafarizadeh A, Saeedi H, Shokouhi B, Baradaran B.   +6 more
europepmc   +1 more source