Results 261 to 270 of about 203,682 (360)

Monoclonal humanized monovalent antibody blocking therapy for anti-NMDA receptor encephalitis. [PDF]

open access: yesNat Commun
Kanno A   +38 more
europepmc   +1 more source

Early adversity and the comorbidity between metabolic disease and psychopathology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas   +1 more
wiley   +1 more source

The causative role of amyloidosis in the cardiac complications of Alzheimer's disease: a comprehensive systematic review

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker   +2 more
wiley   +1 more source

Generalised Hodgkin–Huxley model captures human P2X and AMPA receptor currents

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A universal, biophysically interpretable mathematical model for human ionotropic receptors. The generalised Hodgkin–Huxley (gHH) model unifies the mathematical description of all major ligand‐gated ionotropic receptors (P2X1–7, AMPA) across diverse cell types, capturing activation, inactivation, desensitisation and recovery ...
Alireza Poshtkohi, Brian D. Gulbransen
wiley   +1 more source

Neuronal THY1 Signaling Maintains Astrocytes in a Quiescent State

open access: yesGlia, Volume 74, Issue 1, January 2026.
THY1‐bearing neurons keep astrocytes in a quiescent state via the interaction with ITGB1. Depletion of THY1 supports the development of a partially activated astrocyte phenotype. Neuronal THY1 is involved in the maintenance and restoration of tissue homeostasis in the brain. ABSTRACT THY1 is a cell surface protein of mature neurons.
Juliane Loui   +6 more
wiley   +1 more source

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