Results 271 to 280 of about 203,682 (360)

Ceftriaxone alleviates mitochondrial damage through the inhibition of extrasynaptic NMDA receptor-mediated changes in intracellular calcium levels to improve cognitive deficits in APP/PS1 mice. [PDF]

Alzheimers Res Ther
Liu LR, Li L, Lu LL, Fan SJ, Liu LZ, He RB, Li H, Xian XH, Li WB.   +8 more
europepmc   +1 more source

Perinatal Exposure to the Neonicotinoid Thiacloprid Impacts Transcription of Neuroplasticity and Neuroendocrine Markers in Mice but Not in the Zebrafish Model

Journal of Applied Toxicology, Volume 46, Issue 1, Page 179-197, January 2026.
ABSTRACT Neonicotinoids are widely used insecticides in agriculture, aquaculture, pet care, and urban pest control. Initially developed to selectively target the insect cholinergic system, their extensive use has raised concerns about adverse effects on nontarget vertebrates.
Kirthana Kunikullaya U, Zuzanna M. Baran, Pascal Coumailleau, Laetitia Guillot, Harry W. M. Steinbusch, Fatima Smagulova, Thierry D. Charlier   +6 more
wiley   +1 more source

Bridging the gap: insights into sensorimotor deficits in NMDA receptor antibody encephalitis. [PDF]

J Clin Invest
Opal P, Swanson GT.
europepmc   +1 more source

Lifestyle and Behavioural Intervention Therapy for Enhanced Hippocampal Neuroplasticity

Lifestyle Medicine, Volume 7, Issue 1, January 2026.
ABSTRACT Background The neurogenic and neuroplastic capability of the brain plays a crucial role in mitigating responses to internal and external environmental stimuli. However, this process is inhibited in obesity, neurodegenerative and psychological disorders, the prevalence of which has increased on a global scale.
Ebrahim Samodien, Sylvester Ifeanyi Omoruyi, Brendon Pearce, Melisse Erasmus, Nireshni Chellan   +4 more
wiley   +1 more source

Central Neurophysiological Alterations in Dystrophic mdx Mice Correlate With Reduced Hippocampal Levels of the Endogenous NMDA Receptor Ligand D-Aspartate. [PDF]

J Neurochem
Mastrostefano F, Garofalo M, Nuzzo T, Bruno C, Errico F, Usiello A, De Stefano ME.   +6 more
europepmc   +1 more source

Glutamate Signaling and NMDA Receptor Dynamics in Healthy Aging and Alzheimer’s Disease

Ammarah Baig, Javeria Tanveer, Rukhsana Rubeen, Sadaf Shakoor, Kanza Khan, Kaneez Fatima-Shad   +5 more
openalex   +2 more sources

Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management

Medicinal Research Reviews, Volume 46, Issue 1, Page 272-298, January 2026.
ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh, Shubham Mahajan, Sadikalmahdi Abdella, Rehan Khan, Sanjay Garg   +4 more
wiley   +1 more source

GRIN2B disease-associated mutations disrupt the function of BK channels and NMDA receptor signaling nanodomains. [PDF]

J Gen Physiol
Martínez-Lázaro R, Minguez-Viñas T, Reyes-Carrión A, Gómez R, Alvarez de la Rosa D, Bartolomé-Martín D, Giraldez T.   +6 more
europepmc   +1 more source

Computationally Probing the Role of Time‐Limited Neuronal Plasticity in Early Visual Development

Developmental Science, Volume 29, Issue 1, January 2026.
ABSTRACT In the first months or years of life, newborns learn to perceive their environment at a remarkable pace. This capacity is often attributed to heightened neuronal plasticity that diminishes over time. While this decline in plasticity could be seen as constituting a mere biological constraint, we ask whether it might, in fact, serve an adaptive ...
Marin Vogelsang, Lukas Vogelsang, Pawan Sinha   +2 more
wiley   +1 more source