Results 291 to 300 of about 197,779 (358)

Biomarker for Diagnosis and Monitoring of Treatment Response in Major Depressive Disorder: Changes in Serum L‐Glutamine Levels

Biomedical Chromatography, Volume 39, Issue 9, September 2025.
ABSTRACT Major depressive disorder (MDD) is a mood disorder that causes serious functional impairment. Existing diagnostic methods rely on subjective assessments because of its complex and heterogeneous pathophysiology; therefore, development of objective biomarkers is urgently needed.
Seungyeon Lee, You‐Rim Lee, Sora Mun, Yeeun Yun, Hee‐Gyoo Kang, Jiyeong Lee   +5 more
wiley   +1 more source

Molecular mechanism of ligand gating and opening of NMDA receptor. [PDF]

Nature
Chou TH, Epstein M, Fritzemeier RG, Akins NS, Paladugu S, Ullman EZ, Liotta DC, Traynelis SF, Furukawa H.   +8 more
europepmc   +1 more source

Atypical Presentation of Anti‐NMDAR Encephalitis in an Elderly Male With Dominated Memory Impairment From Damascus Hospital

Clinical Case Reports, Volume 13, Issue 9, September 2025.
ABSTRACT Anti‐N‐methyl‐D‐aspartate receptor (NMDAR) encephalitis is a rare but serious autoimmune disorder that is typically characterized by a broad spectrum of psychiatric and neurological symptoms. In the academic literature, memory deficits often occur alongside psychiatric symptoms, seizures, motor dysfunctions, and other cognitive issues; it is ...
Hamza Warda, Ola Emad Alasmar, Abdulkareem Muhammad Wardeh, Ali Mohammad Ibrahem, Esraa Alsaadi, Heba Alsamara, Anas Jouhar   +6 more
wiley   +1 more source

Screening for Potential Compounds Using Drug-Repurposing of N-Methyl-D-Aspartate (NMDA) Receptor for Autism Spectrum Disorder (ASD). [PDF]

Trop Life Sci Res
Shabudin NSM, Shuid AN.
europepmc   +1 more source

Beyond the tumor: Enhancing pancreatic cancer therapy through glutamine metabolism and innovative drug delivery

Journal of Cell Communication and Signaling, Volume 19, Issue 3, September 2025.
The top row shows key drivers‐KRAS, c‐Myc and HIF‐1a‐alongside gut and tumor microbiota, all converging on glutamine metabolism in PDAC. At the center, glutamine handling is depicted as the linchpin of tumor growth, biosynthesis and immune modulation. The green panel lists major intervention strategies: DON‐loaded nanoparticles, prodrugs (DRP‐104/JHU ...
Min Su, Huan Qin, Jie Shen, Hao An, Yu Cao   +4 more
wiley   +1 more source

Subtype-specific conformational landscape of NMDA receptor gating. [PDF]

Cell Rep
Bleier J, Furtado de Mendonca PR, Habrian CH, Stanley C, Vyklicky V, Isacoff EY.   +5 more
europepmc   +1 more source

Molecular architecture of language‐related cortical areas revealed by integrative proteomic and connectome analyses

Clinical and Translational Medicine, Volume 15, Issue 9, September 2025.
Wu et al. studied why certain brain areas are more connected than others. They found that areas with similar protein patterns tend to work together more closely. Additionally, they found when one area is affected such as in brain tumours, other areas with similar patterns especially contralateral regions might help.
Jinsong Wu, Zixian Wang, Fengjiao Li, Shuolei Bu, Lianglong Sun, Chen Zheng, Zhixin Bai, Luhao Yang, Fangyuan Gong, Jiali Chen, Yien Huang, Wanjing Li, Guoquan Yan, Weiwei Xian, Jiaxuan Yang, Shuai Wu, Kemin Zhu, Wenke Fan, Qiong Liu, Guomin Zhou, Gong‐Hong Wei, Wensheng Li, Jing Yan, Jingliang Cheng, Russell G. Snell, Maurice A. Curtis, Tianye Jia, Binke Yuan, Yong He, Weijiang Zhang, Linya You   +30 more
wiley   +1 more source

Investigating the L-Glu-NMDA receptor-H₂S-NMDA receptor pathway that regulates gastric function in rats' nucleus ambiguus. [PDF]

Front Pharmacol
Sun H, Li C, Shi Y, Wang Y, Li J, Fan L, Yu Y, Ji X, Gao X, Hou K, Li Y.   +10 more
europepmc   +1 more source