Results 51 to 60 of about 887,442 (314)

Ultrafast Laplace NMR to study metal–ligand interactions in reversible polarisation transfer from parahydrogen [PDF]

, 2021
Laplace Nuclear Magnetic Resonance (NMR) can determine relaxation parameters and diffusion constants, giving valuable information about molecular structure and dynamics. Information about relaxation times (T₁ and T₂) and the self-diffusion coefficient (D)
Zhivonitko, Vladimir V., Tickner, Ben. J., Telkki, Ville-Veikko, Ville-Veikko Telkki, Ben. J. Tickner, Vladimir V. Zhivonitko   +5 more
core   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

High-resolution NMR studies of structure and dynamics of human ERp27 indicate extensive interdomain flexibility [PDF]

, 2013
ERp27 (endoplasmic reticulum protein 27.7 kDa) is a homologue of PDI (protein disulfide-isomerase) localized to the endoplasmic reticulum. ERp27 is predicted to consist of two thioredoxin-fold domains homologous with the non-catalytic b and b' domains of
Freedman, R. B., Williamson, Richard A., Amin, Nader T, Rowe, Michelle L, Howard, Mark J., Howard, Mark J, Wallis, A. Katrine, Amin, Nader T., Williamson, Richard A, Freedman, Robert B, Freedman, Robert B., Wallis, Anne Katrine, Wallis, A K, Wells, Stephen A., Rowe, Michelle L., Wells, Stephen A; id_orcid   +15 more
core   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Glycyrrhetinic acid/Enoxolone 900_400MHz DMSOd6 NMR data

NMR data for glycyrrhetinic acid (Enoxolone) in DMSO-d6. The dataset contains the 1D 1H and 13C, as well as 2D COSY, HSQC, HMBC acquired at 900MHz (Bruker Avance spectrometer, equipped with cryoprobe 5 mm CPTCI); in addition, 1D: 1H and 13C acquired at ...
Lankin, David, Pauli, Guido, Kim, Seon Beom, Simmler, Charlotte   +3 more
core   +1 more source

NMR studies of fluoropolymers and of polyaniline [PDF]

, 1998
This thesis presents a study of two polymers, poly(trifluoroethylene) (PTrFE) and polyaniline (PANi), by means of Nuclear Magnetic Resonance Spectroscopy (NMR).The first part of the thesis focusses on investigations in connection with the fluoro polymer.
Reinsberg, Stefan A.
core  

From Zero to Hero: The Cyanide-Free Formation of Amino Acids and Amides from Acetylene, Ammonia and Carbon Monoxide in Aqueous Environments in a Simulated Hadean Scenario

Life
Amino acids are one of the most important building blocks of life. During the biochemical process of translation, cells sequentially connect amino acids via amide bonds to synthesize proteins, using the genetic information in messenger RNA (mRNA) as a ...
Christian Seitz, Thomas Geisberger, Alexander Richard West, Jessica Fertl, Wolfgang Eisenreich, Claudia Huber   +5 more
doaj   +1 more source

Intramolecular hydrogen bonds in 1,4-dihydropyridine derivatives [PDF]

Royal Society Open Science, 2018
1,4-Dihydropyridine (1,4-DHP) derivatives have been synthesized and characterized by 1H, 13C, 15N nuclear magnetic resonance (NMR) spectroscopy, secondary proton/deuterium 13C isotope shifts, variable temperature 1H NMR experiments and quantum-chemical ...
M. Petrova, R. Muhamadejev, B. Vigante, G. Duburs, Edvards Liepinsh   +4 more
doaj   +1 more source

Dysregulated Cholesterol Metabolism, Chronic Inflammation, and Disability in Severe Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Dysregulated lipid metabolism, which can affect remyelination and neural repair, has not been extensively investigated in progressive multiple sclerosis (PMS). The goal was to examine whether dysregulated cholesterol metabolism was associated with disability in PMS. Methods The study sample comprised 53 Severe PMS patients (Expanded
Taylor R. Wicks, Mujeeb Shittu, Anna Wolska, Diala Ghazal, Bianca Weinstock‐Guttman, Alexander Burnham, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +8 more
wiley   +1 more source

Solid-state NMR studies of absorption onto activated carbon [PDF]

, 1995
This is a study of adsorption on three activated carbon substrates using solid- state NMR. The adsorbates used as probe molecules included a range of phosphates, phosphonates and deuterated water.
Thompson, Timothy V.
core